iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073058

UUCD1 version

UUC-OrA-00773

Ensembl Protein ID

ENSOANP00000016397.2

UniProt Accession

F6RM09; F6RM09_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000010336.3	ENSOANT00000016400.3	ENSOANP00000016397.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-33	115.5	1	94
UBD/Alpha-Helix/UBA	3.60e-11	43.1	109	147

Active Site

Position(s)	Description	Evidence
40	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 44   ggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
           gg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e
   Q: 1    GGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPE 87
           689*******************************99********9..****************************************** PP
   S: 132  eykkkvr 138
           ++k+++r
   Q: 88   MFKQTAR 94
           ****986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 109  EYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 147
           6789*********************************97 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

GGRYQLEIKI PETYPFNPPK VRFITKIWHP NISSVTGAIC LDILKDQWAA AMTLRTVLLS 60
LQALLAAAEP DDPQDAVVAN QYKQNPEMFK QTARLWAHVY AGAPVSSPEY TKKIENLCAM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATTTTAGG AGGAAGATAT CAGCTAGAGA TAAAAATACC AGAAACATAT CCATTCAACC 60
CTCCTAAGGT ATAGTAAGTG TATTTTTTTA CTCTCATATG TACATCTGTT CATTTTCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001286	Ailuropoda melanoleuca	100.00	8.00e-79	285.00
IUUC-Atr-003063	Amborella trichopoda	53.79	3.00e-31	127.00
IUUC-Apl-004122	Anas platyrhynchos	99.32	4.00e-78	283.00
IUUC-Aca-004565	Anolis carolinensis	100.00	1.00e-78	284.00
IUUC-Aly-006390	Arabidopsis lyrata	52.03	1.00e-35	141.00
IUUC-Ath-006637	Arabidopsis thaliana	50.00	1.00e-32	131.00
IUUC-Acl-008189	Aspergillus clavatus	54.46	9.00e-26	109.00
IUUC-Afl-008489	Aspergillus flavus	41.61	3.00e-26	111.00
IUUC-Afu-008850	Aspergillus fumigatus	40.25	2.00e-25	108.00
IUUC-Ani-009361	Aspergillus nidulans	55.91	4.00e-23	100.00
IUUC-Ang-009548	Aspergillus niger	54.55	7.00e-25	106.00
IUUC-Aor-010105	Aspergillus oryzae	41.61	3.00e-26	111.00
IUUC-Ate-010389	Aspergillus terreus	40.88	2.00e-25	108.00
IUUC-Ame-011454	Astyanax mexicanus	96.62	1.00e-76	278.00
IUUC-Bta-012992	Bos taurus	100.00	8.00e-79	285.00
IUUC-Bci-013806	Botrytis cinerea	41.82	2.00e-26	111.00
IUUC-Bdi-015024	Brachypodium distachyon	52.70	2.00e-31	128.00
IUUC-Bol-015985	Brassica oleracea	52.03	1.00e-35	142.00
IUUC-Bra-016805	Brassica rapa	52.03	6.00e-36	142.00
IUUC-Cel-018353	Caenorhabditis elegans	53.06	4.00e-39	153.00
IUUC-Cja-019051	Callithrix jacchus	99.32	5.00e-78	282.00
IUUC-Cfa-020016	Canis familiaris	100.00	8.00e-79	285.00
IUUC-Cpo-022026	Cavia porcellus	100.00	8.00e-79	285.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	54.42	2.00e-33	134.00
IUUC-Csa-023059	Chlorocebus sabaeus	100.00	8.00e-79	285.00
IUUC-Cho-024276	Choloepus hoffmanni	96.60	2.00e-73	266.00
IUUC-Cin-025598	Ciona intestinalis	65.97	2.00e-40	158.00
IUUC-Csv-025831	Ciona savignyi	66.67	4.00e-40	156.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	52.68	7.00e-27	113.00
IUUC-Dre-027803	Danio rerio	96.62	6.00e-76	276.00
IUUC-Dno-029169	Dasypus novemcinctus	100.00	4.00e-78	282.00
IUUC-Dor-030382	Dipodomys ordii	81.08	1.00e-57	214.00
IUUC-Dme-032003	Drosophila melanogaster	67.35	4.00e-48	183.00
IUUC-Ete-032868	Echinops telfairi	88.44	1.00e-58	218.00
IUUC-Eca-033428	Equus caballus	100.00	8.00e-79	285.00
IUUC-Eeu-035103	Erinaceus europaeus	73.44	5.00e-49	185.00
IUUC-Fca-035366	Felis catus	100.00	8.00e-79	285.00
IUUC-Fal-037016	Ficedula albicollis	100.00	8.00e-79	285.00
IUUC-Gmo-039135	Gadus morhua	95.27	2.00e-75	274.00
IUUC-Ggr-039768	Gaeumannomyces graminis	53.40	3.00e-23	101.00
IUUC-Gga-041018	Gallus gallus	99.32	1.00e-78	284.00
IUUC-Gac-041503	Gasterosteus aculeatus	95.95	3.00e-76	276.00
IUUC-Gma-042779	Glycine max	53.42	7.00e-35	139.00
IUUC-Ggo-045032	Gorilla gorilla	100.00	8.00e-79	285.00
IUUC-Hsa-046490	Homo sapiens	100.00	8.00e-79	285.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	100.00	8.00e-79	285.00
IUUC-Lch-050588	Latimeria chalumnae	68.72	4.00e-62	229.00
IUUC-Lpe-051070	Leersia perrieri	52.70	2.00e-23	101.00
IUUC-Loc-052549	Lepisosteus oculatus	96.62	1.00e-76	278.00
IUUC-Laf-053688	Loxodonta africana	100.00	1.00e-78	285.00
IUUC-Mcc-055606	Macaca mulatta	100.00	8.00e-79	285.00
IUUC-Mor-056946	Magnaporthe oryzae	39.07	1.00e-21	95.50
IUUC-Mpo-057441	Magnaporthe poae	55.56	5.00e-23	100.00
IUUC-Mtr-058002	Medicago truncatula	53.42	1.00e-34	139.00
IUUC-Mga-059254	Meleagris gallopavo	99.32	4.00e-78	282.00
IUUC-Mmr-061211	Microcebus murinus	100.00	8.00e-79	285.00
IUUC-Mdo-062458	Monodelphis domestica	99.32	1.00e-77	281.00
IUUC-Mmu-063648	Mus musculus	100.00	8.00e-79	285.00
IUUC-Mac-065447	Musa acuminata	54.05	2.00e-33	134.00
IUUC-Mpu-066407	Mustela putorius furo	100.00	4.00e-78	283.00
IUUC-Mlu-067682	Myotis lucifugus	100.00	8.00e-79	285.00
IUUC-Nfi-068517	Neosartorya fischeri	40.25	1.00e-25	109.00
IUUC-Ncr-068749	Neurospora crassa	55.77	1.00e-28	118.00
IUUC-Nle-069712	Nomascus leucogenys	99.32	2.00e-78	283.00
IUUC-Opr-070651	Ochotona princeps	100.00	8.00e-79	285.00
IUUC-Ont-071595	Oreochromis niloticus	95.95	3.00e-76	276.00
IUUC-Ocu-074939	Oryctolagus cuniculus	100.00	8.00e-79	285.00
IUUC-Oba-075530	Oryza barthii	53.38	1.00e-23	102.00
IUUC-Obr-076838	Oryza brachyantha	52.70	2.00e-23	101.00
IUUC-Ogl-077606	Oryza glaberrima	53.38	1.00e-23	102.00
IUUC-Ogu-078238	Oryza glumaepatula	53.38	1.00e-23	102.00
IUUC-Oin-079643	Oryza indica	53.38	3.00e-23	100.00
IUUC-Ome-081274	Oryza meridionalis	53.38	1.00e-23	102.00
IUUC-Oni-082651	Oryza nivara	53.38	1.00e-23	102.00
IUUC-Opu-083933	Oryza punctata	53.38	2.00e-23	101.00
IUUC-Oru-085054	Oryza rufipogon	53.38	3.00e-23	100.00
IUUC-Osa-085716	Oryza sativa	53.38	3.00e-23	100.00
IUUC-Ola-087043	Oryzias latipes	95.95	3.00e-76	276.00
IUUC-Oga-088897	Otolemur garnettii	100.00	1.00e-78	284.00
IUUC-Oar-089673	Ovis aries	100.00	2.00e-78	284.00
IUUC-Ptr-091295	Pan troglodytes	100.00	8.00e-79	285.00
IUUC-Pan-092034	Papio anubis	100.00	2.00e-78	283.00
IUUC-Psi-093498	Pelodiscus sinensis	100.00	8.00e-79	285.00
IUUC-Pma-094115	Petromyzon marinus	86.49	6.00e-67	245.00
IUUC-Ppa-095326	Physcomitrella patens	50.68	6.00e-30	122.00
IUUC-Pfo-096940	Poecilia formosa	95.27	1.00e-75	275.00
IUUC-Pab-098279	Pongo abelii	100.00	8.00e-79	285.00
IUUC-Pop-099543	Populus trichocarpa	53.38	4.00e-36	143.00
IUUC-Pca-100782	Procavia capensis	99.32	1.00e-76	278.00
IUUC-Ppe-101789	Prunus persica	51.35	6.00e-35	139.00
IUUC-Pva-102147	Pteropus vampyrus	100.00	3.00e-52	196.00
IUUC-Rno-104984	Rattus norvegicus	100.00	8.00e-79	285.00
IUUC-Sha-106848	Sarcophilus harrisii	100.00	3.00e-78	283.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	44.85	4.00e-30	124.00
IUUC-Smo-109656	Selaginella moellendorffii	53.06	8.00e-31	125.00
IUUC-Sit-110639	Setaria italica	51.35	4.00e-30	123.00
IUUC-Sly-110978	Solanum lycopersicum	52.70	8.00e-36	142.00
IUUC-Stu-112088	Solanum tuberosum	52.70	3.00e-36	143.00
IUUC-Sar-113285	Sorex araneus	81.08	3.00e-57	213.00
IUUC-Sbi-113986	Sorghum bicolor	51.35	5.00e-30	123.00
IUUC-Ssc-116314	Sus scrofa	100.00	8.00e-79	285.00
IUUC-Tgu-117427	Taeniopygia guttata	100.00	2.00e-78	283.00
IUUC-Tru-118618	Takifugu rubripes	91.89	2.00e-73	267.00
IUUC-Tsy-119208	Tarsius syrichta	100.00	7.00e-79	285.00
IUUC-Tni-119667	Tetraodon nigroviridis	95.95	3.00e-76	276.00
IUUC-Tca-121446	Theobroma cacao	53.38	2.00e-36	144.00
IUUC-Tae-124726	Triticum aestivum	53.38	5.00e-24	103.00
IUUC-Tme-127024	Tuber melanosporum	54.31	6.00e-30	123.00
IUUC-Tbe-127752	Tupaia belangeri	100.00	1.00e-78	284.00
IUUC-Ttr-128287	Tursiops truncatus	100.00	2.00e-78	283.00
IUUC-Vpa-130481	Vicugna pacos	100.00	1.00e-78	285.00
IUUC-Vvi-131429	Vitis vinifera	51.03	2.00e-33	134.00
IUUC-Xtr-132710	Xenopus tropicalis	78.67	9.00e-65	238.00
IUUC-Xma-134165	Xiphophorus maculatus	95.27	8.00e-76	275.00
IUUC-Zma-135733	Zea mays	50.00	3.00e-28	117.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence