iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069402

Ensembl Protein ID

ENSNLEP00000015923.1

UniProt Accession

G1RRQ8; G1RRQ8_NOMLE

Genbank Protein ID

ENSNLEP00000015923

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01123307

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000013134.1	ENSNLET00000016738.1	ENSNLEP00000015923.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-36	122.0	175	212
UBD/Beta-Prp	4.90e-55	186.8	279	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 175  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 212
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsf 102
           +++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s++f
   Q: 279  YMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSIQF 367
           7899999**********999999988777778888888755522888888**************99999******************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           + +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ l 
   Q: 368  CNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLM 456
           ************************99998999********998877777888************************************* PP
   S: 177  gghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 457  G-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 534
           9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

PTPCLPAELY FLIARYLSAG PCRRAAQVLV QELEQYQLLP KRLDWEGNEH NRSYEELVLS 60
NKHVAPDHLL QICQRIGPML DKEIPPSISR VTSLLGAGRQ SLLRTAKDCR HTVWKGSAFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGACTCCCT GTCTTCCCGC AGAGCTGTAC TTCCTCATCG CCCGGTACCT ATCGGCGGGC 60
CCATGTCGGA GAGCGGCCCA GGTGAGTGCG GGCCCACGGG CGGCTGCGGA CTTGGCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.71	6.00e-62	233.00
IUUC-Aml-002332	Ailuropoda melanoleuca	93.01	0.00e+00	2910.00
IUUC-Atr-002600	Amborella trichopoda	29.62	1.00e-66	249.00
IUUC-Apl-004083	Anas platyrhynchos	69.51	0.00e+00	1954.00
IUUC-Aca-004348	Anolis carolinensis	72.97	0.00e+00	1943.00
IUUC-Aly-006517	Arabidopsis lyrata	30.83	8.00e-73	269.00
IUUC-Ath-006577	Arabidopsis thaliana	30.43	5.00e-72	266.00
IUUC-Ame-010718	Astyanax mexicanus	70.38	0.00e+00	1164.00
IUUC-Bta-013217	Bos taurus	92.37	0.00e+00	2963.00
IUUC-Bdi-014797	Brachypodium distachyon	29.26	5.00e-58	220.00
IUUC-Bol-015737	Brassica oleracea	29.84	3.00e-71	264.00
IUUC-Bra-017961	Brassica rapa	29.80	2.00e-70	261.00
IUUC-Cja-019966	Callithrix jacchus	95.84	0.00e+00	3093.00
IUUC-Cfa-021037	Canis familiaris	92.16	0.00e+00	2963.00
IUUC-Cpo-021934	Cavia porcellus	91.78	0.00e+00	2747.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.62	7.00e-35	142.00
IUUC-Csa-023352	Chlorocebus sabaeus	96.52	0.00e+00	2838.00
IUUC-Cho-024690	Choloepus hoffmanni	84.98	0.00e+00	907.00
IUUC-Dre-028205	Danio rerio	68.06	0.00e+00	1138.00
IUUC-Dno-028938	Dasypus novemcinctus	88.87	0.00e+00	2887.00
IUUC-Eca-034349	Equus caballus	92.65	0.00e+00	2860.00
IUUC-Fca-035485	Felis catus	91.23	0.00e+00	2849.00
IUUC-Fal-037307	Ficedula albicollis	74.25	0.00e+00	2351.00
IUUC-Gma-043340	Glycine max	30.36	7.00e-70	259.00
IUUC-Ggo-045500	Gorilla gorilla	97.18	0.00e+00	3096.00
IUUC-Hsa-046350	Homo sapiens	97.64	0.00e+00	3088.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.07	0.00e+00	1161.00
IUUC-Lch-049662	Latimeria chalumnae	66.86	0.00e+00	2077.00
IUUC-Lpe-051619	Leersia perrieri	31.23	4.00e-70	260.00
IUUC-Loc-052853	Lepisosteus oculatus	66.20	0.00e+00	1833.00
IUUC-Laf-053848	Loxodonta africana	91.41	0.00e+00	2899.00
IUUC-Mcc-054638	Macaca mulatta	96.44	0.00e+00	3077.00
IUUC-Meu-056739	Macropus eugenii	79.91	0.00e+00	1110.00
IUUC-Mtr-058094	Medicago truncatula	30.62	9.00e-72	266.00
IUUC-Mga-060165	Meleagris gallopavo	77.61	0.00e+00	2289.00
IUUC-Mmr-061227	Microcebus murinus	93.43	0.00e+00	3024.00
IUUC-Mdo-062074	Monodelphis domestica	77.09	0.00e+00	2570.00
IUUC-Mmu-064075	Mus musculus	86.19	0.00e+00	2846.00
IUUC-Mac-065343	Musa acuminata	31.02	7.00e-75	276.00
IUUC-Mpu-066643	Mustela putorius furo	92.07	0.00e+00	2832.00
IUUC-Mlu-067735	Myotis lucifugus	90.17	0.00e+00	2836.00
IUUC-Oan-072954	Ornithorhynchus anatinus	82.01	0.00e+00	2609.00
IUUC-Ocu-074456	Oryctolagus cuniculus	90.86	0.00e+00	2963.00
IUUC-Oba-075709	Oryza barthii	30.17	3.00e-60	228.00
IUUC-Obr-076619	Oryza brachyantha	30.90	2.00e-70	261.00
IUUC-Opu-083233	Oryza punctata	30.47	9.00e-65	243.00
IUUC-Oru-085195	Oryza rufipogon	30.17	2.00e-60	228.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.61	1.00e-56	215.00
IUUC-Oga-087938	Otolemur garnettii	83.73	0.00e+00	2661.00
IUUC-Oar-090214	Ovis aries	92.25	0.00e+00	2852.00
IUUC-Ptr-091213	Pan troglodytes	97.01	0.00e+00	3051.00
IUUC-Pan-092444	Papio anubis	95.58	0.00e+00	3052.00
IUUC-Pma-094427	Petromyzon marinus	67.38	3.00e-132	464.00
IUUC-Ppa-095793	Physcomitrella patens	30.25	1.00e-73	272.00
IUUC-Pfo-097318	Poecilia formosa	62.84	0.00e+00	1783.00
IUUC-Pab-097573	Pongo abelii	95.21	0.00e+00	2974.00
IUUC-Pop-099672	Populus trichocarpa	31.03	4.00e-72	267.00
IUUC-Pca-100759	Procavia capensis	70.17	0.00e+00	1131.00
IUUC-Ppe-101849	Prunus persica	29.82	3.00e-73	271.00
IUUC-Pva-102782	Pteropus vampyrus	91.39	0.00e+00	2883.00
IUUC-Rno-105687	Rattus norvegicus	86.00	0.00e+00	2781.00
IUUC-Sly-111348	Solanum lycopersicum	30.56	2.00e-75	278.00
IUUC-Sar-113519	Sorex araneus	80.63	0.00e+00	1776.00
IUUC-Sbi-114195	Sorghum bicolor	29.09	2.00e-58	220.00
IUUC-Tsy-118921	Tarsius syrichta	89.92	0.00e+00	2022.00
IUUC-Tca-121098	Theobroma cacao	31.11	1.00e-78	288.00
IUUC-Tae-125478	Triticum aestivum	30.45	1.00e-70	262.00
IUUC-Tur-126809	Triticum urartu	30.42	2.00e-68	255.00
IUUC-Tbe-127663	Tupaia belangeri	86.18	0.00e+00	1206.00
IUUC-Ttr-128561	Tursiops truncatus	89.16	0.00e+00	2763.00
IUUC-Vpa-130444	Vicugna pacos	88.52	0.00e+00	2629.00
IUUC-Vvi-131362	Vitis vinifera	31.02	3.00e-73	271.00
IUUC-Xtr-132278	Xenopus tropicalis	54.63	0.00e+00	1580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence