iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Vvi-131365

UUCD1 version

UUC-ViV-00935

Ensembl Protein ID

VIT_15s0046g00400.t01

UniProt Accession

D7UCU0; D7UCU0_VITVI

Genbank Protein ID

CBI40555.3

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

FN596755

Gene Name

VIT_15s0046g00400

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VIT_15s0046g00400	VIT_15s0046g00400.t01	VIT_15s0046g00400.t01

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	37.89	5.00e-39	158.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Vitis vinifera

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MGNRVADLHS LTTFQELLKC PVCFNFMPSP IYQCHNGHTL CSSCKARVLN KCPTCRHQLG 60
DIRCLALEKM AESLQLHCKY EEFGCPEIIP YHTKLMHEDS CNFRPYSCPW YGCPCSAVGD 120

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Nucleotide Sequence
(Fasta)

GCGTTGGGTG AATGGGAAAC CGCGTCGCAG ATCTTCACTC CCTAACCACG TTCCAGGAGC 60
TGCTCAAGTG CCCCGTTTGC TTCAACTTTA TGCCGTCTCC AATTTATCAG GTTTGCTTTT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024933	Choloepus hoffmanni	36.82	1.00e-37	149.00
IUUC-Dor-030489	Dipodomys ordii	32.93	1.00e-20	92.00
IUUC-Dme-031700	Drosophila melanogaster	37.34	9.00e-37	146.00
IUUC-Gmo-039091	Gadus morhua	36.36	3.00e-36	144.00
IUUC-Meu-055922	Macropus eugenii	36.40	1.00e-36	145.00
IUUC-Mdo-061971	Monodelphis domestica	37.24	7.00e-38	149.00
IUUC-Pca-100328	Procavia capensis	35.98	7.00e-36	143.00
IUUC-Pva-103132	Pteropus vampyrus	29.37	2.00e-12	65.50
IUUC-Ssc-116441	Sus scrofa	36.82	2.00e-37	148.00
IUUC-Tsy-119548	Tarsius syrichta	29.25	2.00e-07	48.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence