iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062139

Ensembl Protein ID

ENSMODP00000027552.1

UniProt Accession

F6PJD6; F6PJD6_MONDO

Protein Name

Uncharacterized protein

Gene Name

LOC100027495

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000022847.1	ENSMODT00000029092.1	ENSMODP00000027552.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-28	96.8	303	341
E3 adaptor/Cullin RING/APC_C/CDC20	9.00e-141	468.6	167	471

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ +v++l++ +d  ll+sG++D+++ vW+ + +++++
   Q: 303  GHKQEVCGLKWsTDhQLLASGGNDNKLLVWNNSNFRPVQ 341
           8**********98889***************88888776 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvl+a  lrddfylnLldWss n++av+L ++vylwsa+t++v++l dl  e+d+vtsv w e+g+llavGt+kg v+i+Dv+++kk
   Q: 167  PFKVLEASGLRDDFYLNLLDWSSLNIVAVGLSTCVYLWSACTSQVTRLFDLcAEGDSVTSVGWYEKGNLLAVGTQKGLVQIWDVDAEKK 255
           689************************************************9************************************* PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           v+t++gh+arvgaL+W a+++ssGsrd +il+rd+r++ l+  + lq+h+qevCGlkw++d++lLasGGnDn++ vw++s+ +P++++ 
   Q: 256  VSTMEGHKARVGALAWYADQISSGSRDTRILQRDIRASPLQSqRWLQGHKQEVCGLKWSTDHQLLASGGNDNKLLVWNNSNFRPVQQYV 344
           *****************************************97889******************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           +hkaavkaiawsP+q++lLasGGG+aDrci+fwntltg+ l++idtgsqvc+l+ws++ +elvsthG+aen+i++wkypsl +va+l+g
   Q: 345  THKAAVKAIAWSPHQHGLLASGGGSADRCIRFWNTLTGQPLQRIDTGSQVCNLAWSRHDNELVSTHGYAENQIAVWKYPSLVQVAKLTG 433
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h +Rvl+la+spdg+aivt+agD +lrfw++f k +++
   Q: 434  HLYRVLYLAVSPDGQAIVTGAGDKSLRFWNVFRKARSQ 471
           ********************************998765 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

TDYQRLCLTP AGPREQNPRN PTSVKAKMSW SLTPFSFPVS SHGKHGDRYI PSRAGANWNL 60
HFHSTADTDN SPGQKQKEDT WGNGQDASVY STLLKNELLE AKTPTVEEPK TSGIPKKNLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGACTACC AAAGGTTGTG TCTAACCCCG GCAGGACCCA GGGAGCAGAA TCCAAGAAAT 60
CCGACTAGTG TGAAAGCCAA GATGAGCTGG AGTCTGACGC CATTCAGTTT TCCAGTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence