iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000005077.2	ENSOCUT00000005081.2	ENSOCUP00000018249.1
ENSOCUG00000005077.2	ENSOCUT00000005075.2	ENSOCUP00000004396.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.30e-09	37.2	103	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 103  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 142
           **********999999*************......**********7 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

QGSKQPPGSP LSREEGEAPA PAPAPEGRRR SRRVRLRGSC RHRPSFLGRR ELAASSPAGA 60
APASPEIMAS AAKEFKMDNF SPKAGTSKLQ QTVPADASPD SKCPICLDRF DNVSYLDRCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCGA AGCAGCCGCC GGGGTCTCCG CTGTCTCGCG AGGAGGGTGA AGCGCCGGCG 60
CCGGCTCCCG CGCCTGAGGG TAGGCGGAGA AGTCGCCGGG TCCGCCTTCG CGGATCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	56.20
IUUC-Aml-002240	Ailuropoda melanoleuca	89.47	0.00e+00	907.00
IUUC-Atr-002964	Amborella trichopoda	34.38	5.00e-13	67.80
IUUC-Apl-003666	Anas platyrhynchos	63.61	3.00e-141	496.00
IUUC-Aca-005305	Anolis carolinensis	65.88	6.00e-150	525.00
IUUC-Aly-005926	Arabidopsis lyrata	36.17	6.00e-11	60.80
IUUC-Ath-007299	Arabidopsis thaliana	35.11	2.00e-11	62.80
IUUC-Ame-011109	Astyanax mexicanus	52.94	8.00e-115	408.00
IUUC-Bta-012637	Bos taurus	91.57	0.00e+00	913.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	1.00e-11	63.20
IUUC-Bol-015307	Brassica oleracea	32.98	6.00e-10	57.80
IUUC-Bra-017073	Brassica rapa	44.90	2.00e-08	52.00
IUUC-Cja-019105	Callithrix jacchus	93.03	0.00e+00	985.00
IUUC-Cfa-021203	Canis familiaris	89.63	0.00e+00	903.00
IUUC-Cpo-022335	Cavia porcellus	85.22	0.00e+00	823.00
IUUC-Csa-023870	Chlorocebus sabaeus	91.51	0.00e+00	969.00
IUUC-Cho-024870	Choloepus hoffmanni	88.30	0.00e+00	851.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	3.00e-07	50.80
IUUC-Dre-027535	Danio rerio	53.65	3.00e-120	426.00
IUUC-Dno-028963	Dasypus novemcinctus	93.13	0.00e+00	865.00
IUUC-Dor-030239	Dipodomys ordii	91.79	0.00e+00	779.00
IUUC-Dme-031941	Drosophila melanogaster	31.93	2.00e-37	151.00
IUUC-Ete-032300	Echinops telfairi	83.30	0.00e+00	1145.00
IUUC-Eca-033690	Equus caballus	91.05	0.00e+00	901.00
IUUC-Eeu-035257	Erinaceus europaeus	87.52	0.00e+00	873.00
IUUC-Fca-036383	Felis catus	89.76	0.00e+00	912.00
IUUC-Fal-037209	Ficedula albicollis	69.65	2.00e-161	562.00
IUUC-Gmo-039416	Gadus morhua	53.40	6.00e-120	424.00
IUUC-Gga-041267	Gallus gallus	71.62	4.00e-173	602.00
IUUC-Gac-042227	Gasterosteus aculeatus	52.69	6.00e-117	414.00
IUUC-Gma-042777	Glycine max	32.61	4.00e-09	55.10
IUUC-Ggo-044445	Gorilla gorilla	93.04	0.00e+00	981.00
IUUC-Hsa-045844	Homo sapiens	93.21	0.00e+00	982.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	5.00e-11	58.50
IUUC-Itr-048818	Ictidomys tridecemlineatus	90.32	0.00e+00	915.00
IUUC-Lch-050031	Latimeria chalumnae	67.56	5.00e-168	585.00
IUUC-Lpe-051274	Leersia perrieri	37.74	8.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	58.40	2.00e-142	499.00
IUUC-Laf-053820	Loxodonta africana	92.24	0.00e+00	871.00
IUUC-Mcc-054800	Macaca mulatta	91.36	0.00e+00	967.00
IUUC-Meu-056806	Macropus eugenii	71.63	0.00e+00	635.00
IUUC-Mtr-058378	Medicago truncatula	34.58	7.00e-13	67.40
IUUC-Mla-059017	Melampsora laricipopulina	36.07	3.00e-09	56.20
IUUC-Mvi-060417	Microbotryum violaceum	24.05	5.00e-17	83.20
IUUC-Mmr-061481	Microcebus murinus	91.71	0.00e+00	925.00
IUUC-Mdo-062219	Monodelphis domestica	81.45	2.00e-109	390.00
IUUC-Mmu-064138	Mus musculus	89.22	0.00e+00	832.00
IUUC-Mac-064635	Musa acuminata	38.57	7.00e-11	59.70
IUUC-Mlu-067088	Myotis lucifugus	88.47	0.00e+00	896.00
IUUC-Nle-069862	Nomascus leucogenys	92.02	0.00e+00	980.00
IUUC-Opr-071076	Ochotona princeps	93.04	0.00e+00	829.00
IUUC-Ont-072225	Oreochromis niloticus	52.38	1.00e-112	400.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.83	1.00e-157	549.00
IUUC-Oba-075429	Oryza barthii	37.68	9.00e-11	60.50
IUUC-Obr-076084	Oryza brachyantha	36.23	3.00e-10	58.90
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.50
IUUC-Ogu-078603	Oryza glumaepatula	37.68	9.00e-11	60.50
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	60.10
IUUC-Oni-082396	Oryza nivara	37.68	9.00e-11	60.50
IUUC-Opu-083698	Oryza punctata	36.62	5.00e-10	58.20
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.50
IUUC-Ola-087377	Oryzias latipes	55.30	5.00e-110	390.00
IUUC-Oga-088059	Otolemur garnettii	87.41	0.00e+00	907.00
IUUC-Oar-089592	Ovis aries	90.62	0.00e+00	899.00
IUUC-Ptr-091233	Pan troglodytes	93.04	0.00e+00	979.00
IUUC-Pan-092743	Papio anubis	91.51	0.00e+00	968.00
IUUC-Psi-093669	Pelodiscus sinensis	75.17	0.00e+00	660.00
IUUC-Ppa-095668	Physcomitrella patens	26.67	2.00e-22	99.80
IUUC-Pfo-096706	Poecilia formosa	55.74	5.00e-106	378.00
IUUC-Pop-098813	Populus trichocarpa	24.41	5.00e-12	64.70
IUUC-Pca-100967	Procavia capensis	89.47	0.00e+00	810.00
IUUC-Ppe-101922	Prunus persica	35.06	5.00e-09	54.30
IUUC-Pva-102982	Pteropus vampyrus	91.34	0.00e+00	924.00
IUUC-Pgr-103551	Puccinia graminis	38.46	7.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	31.94	1.00e-07	50.10
IUUC-Rno-105730	Rattus norvegicus	87.35	0.00e+00	794.00
IUUC-Sha-106588	Sarcophilus harrisii	73.10	1.00e-180	626.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.70
IUUC-Smo-109039	Selaginella moellendorffii	24.16	3.00e-18	86.30
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.80
IUUC-Stu-112898	Solanum tuberosum	42.37	9.00e-09	55.80
IUUC-Sar-113622	Sorex araneus	89.50	2.00e-155	543.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	91.36	0.00e+00	880.00
IUUC-Tgu-117180	Taeniopygia guttata	64.41	2.00e-166	579.00
IUUC-Tru-118393	Takifugu rubripes	53.58	8.00e-121	427.00
IUUC-Tsy-119408	Tarsius syrichta	93.42	0.00e+00	936.00
IUUC-Tni-120664	Tetraodon nigroviridis	54.80	6.00e-120	424.00
IUUC-Tca-121712	Theobroma cacao	26.81	2.00e-16	79.30
IUUC-Tae-122787	Triticum aestivum	38.57	9.00e-11	60.80
IUUC-Tbe-127301	Tupaia belangeri	83.36	0.00e+00	814.00
IUUC-Ttr-128204	Tursiops truncatus	91.77	0.00e+00	931.00
IUUC-Uma-129420	Ustilago maydis	42.47	9.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	91.41	0.00e+00	901.00
IUUC-Vvi-131157	Vitis vinifera	38.27	8.00e-12	64.30
IUUC-Xtr-132845	Xenopus tropicalis	67.90	5.00e-172	597.00
IUUC-Xma-133439	Xiphophorus maculatus	54.42	3.00e-108	386.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	3.00e-06	46.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence