iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090418

Ensembl Protein ID

ENSOARP00000013850.1

UniProt Accession

W5PTR9; W5PTR9_SHEEP

Genbank Protein ID

ENSOARP00000013850

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01062741

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012931.1	ENSOART00000014055.1	ENSOARP00000013850.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.60e-55	186.9	5	139
UBD/UBC-like/UBD_UBC	5.30e-83	276.2	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R  kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  
   Q: 5    RYSKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR-- 90
           6789********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           r  kel+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqw
   Q: 5    RYSKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQW 93
           678************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 142
           ************************************************8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

TAYKRYSKEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY 60
PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGCATACA AAAGATACTC AAAAATATTT TGTATTAGGG ATCCTAAAGA AAATACAATA 60
TTTTAATTCA TTTAATTTTT TAAAATTTGG AGCAGTCTCA TGAAGGAATT TAATGTCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001563	Ailuropoda melanoleuca	97.95	3.00e-83	300.00
IUUC-Apl-003639	Anas platyrhynchos	99.29	4.00e-81	292.00
IUUC-Aca-005254	Anolis carolinensis	97.95	3.00e-83	300.00
IUUC-Bta-013467	Bos taurus	97.95	3.00e-83	300.00
IUUC-Cja-019302	Callithrix jacchus	97.95	3.00e-83	300.00
IUUC-Cfa-021087	Canis familiaris	97.95	3.00e-83	300.00
IUUC-Csa-023668	Chlorocebus sabaeus	97.95	3.00e-83	300.00
IUUC-Cho-024987	Choloepus hoffmanni	97.95	3.00e-83	300.00
IUUC-Dno-030067	Dasypus novemcinctus	97.95	3.00e-83	300.00
IUUC-Dor-030474	Dipodomys ordii	97.95	3.00e-83	300.00
IUUC-Ete-032540	Echinops telfairi	97.95	3.00e-83	300.00
IUUC-Eca-034167	Equus caballus	97.95	3.00e-83	300.00
IUUC-Gga-040873	Gallus gallus	97.95	3.00e-83	300.00
IUUC-Hsa-045951	Homo sapiens	97.95	3.00e-83	300.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	97.95	3.00e-83	300.00
IUUC-Laf-053673	Loxodonta africana	99.29	3.00e-81	293.00
IUUC-Mcc-055719	Macaca mulatta	97.95	3.00e-83	300.00
IUUC-Mga-060138	Meleagris gallopavo	99.29	4.00e-81	292.00
IUUC-Mmr-061212	Microcebus murinus	97.95	3.00e-83	300.00
IUUC-Mdo-062402	Monodelphis domestica	100.00	1.00e-81	294.00
IUUC-Mmu-063779	Mus musculus	97.95	3.00e-83	300.00
IUUC-Mpu-065724	Mustela putorius furo	97.95	3.00e-83	300.00
IUUC-Mlu-067573	Myotis lucifugus	99.29	4.00e-81	292.00
IUUC-Nle-069950	Nomascus leucogenys	97.95	3.00e-83	300.00
IUUC-Oan-073149	Ornithorhynchus anatinus	100.00	3.00e-81	293.00
IUUC-Oga-088915	Otolemur garnettii	97.95	3.00e-83	300.00
IUUC-Ptr-091575	Pan troglodytes	97.95	3.00e-83	300.00
IUUC-Pan-092922	Papio anubis	97.95	3.00e-83	300.00
IUUC-Pab-098137	Pongo abelii	97.95	3.00e-83	300.00
IUUC-Pca-100678	Procavia capensis	97.95	3.00e-83	300.00
IUUC-Pva-102770	Pteropus vampyrus	97.95	3.00e-83	300.00
IUUC-Rno-106124	Rattus norvegicus	97.95	3.00e-83	300.00
IUUC-Sha-106489	Sarcophilus harrisii	99.29	8.00e-82	295.00
IUUC-Sar-113557	Sorex araneus	100.00	8.00e-81	291.00
IUUC-Tgu-117399	Taeniopygia guttata	98.61	1.00e-82	297.00
IUUC-Ttr-128363	Tursiops truncatus	97.95	3.00e-83	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence