iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066354

Ensembl Protein ID

ENSMPUP00000000226.1

UniProt Accession

M3XMC6; M3XMC6_MUSPF

Genbank Protein ID

ENSMPUP00000000226

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01077616

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000229.1	ENSMPUT00000000230.1	ENSMPUP00000000226.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-29	100.5	1333	1367
UBD/Beta-Prp	1.90e-43	148.8	1437	1644

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1333 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1367
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +v+Gs+d +i+++d+ +g       
   Q: 1437 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIVTGSKDHYIKMFDVTEGALGTVsp 1522
           56789*********9.999*************************************9888*****************9998765466 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l + +  + l+sg + g +klw++ t   v
   Q: 1523 thnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALGVVPGHPVLLSGCRGGILKLWNVDTFVPV 1607
           7889999999999999999..7799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dl 251
            +++gh+++++ + +   ++++ ++++D+++riW    l
   Q: 1608 GEMKGHDSPINAICVN--STHIFTAADDRTVRIWkarSL 1644
           ***********99888..****************44444 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MWGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIESQ 60
QEQIYTQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIIEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
CCGCCGCCGC CGCGGTTGCC ATTCAAGCGC GCCTCGTCCC CGCCCCAGAT CCTGGGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	97.43	0.00e+00	3117.00
IUUC-Apl-003353	Anas platyrhynchos	83.98	0.00e+00	2645.00
IUUC-Aca-004467	Anolis carolinensis	85.47	0.00e+00	2762.00
IUUC-Bta-013485	Bos taurus	95.02	0.00e+00	2977.00
IUUC-Cel-018402	Caenorhabditis elegans	53.49	6.00e-150	525.00
IUUC-Cja-019385	Callithrix jacchus	92.25	0.00e+00	2942.00
IUUC-Cfa-020986	Canis familiaris	97.30	0.00e+00	3046.00
IUUC-Cpo-022297	Cavia porcellus	91.22	0.00e+00	2872.00
IUUC-Csa-023685	Chlorocebus sabaeus	94.45	0.00e+00	3016.00
IUUC-Cho-024531	Choloepus hoffmanni	94.77	0.00e+00	1102.00
IUUC-Cin-025160	Ciona intestinalis	47.04	3.00e-87	316.00
IUUC-Dno-029972	Dasypus novemcinctus	90.34	0.00e+00	2780.00
IUUC-Ete-032872	Echinops telfairi	80.49	0.00e+00	1048.00
IUUC-Eca-033518	Equus caballus	95.85	0.00e+00	3035.00
IUUC-Fca-036197	Felis catus	96.59	0.00e+00	3036.00
IUUC-Fal-037534	Ficedula albicollis	85.05	0.00e+00	2686.00
IUUC-Gmo-039407	Gadus morhua	66.82	0.00e+00	1944.00
IUUC-Gga-040687	Gallus gallus	82.94	0.00e+00	2618.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.81	0.00e+00	2177.00
IUUC-Ggo-044457	Gorilla gorilla	94.83	0.00e+00	2989.00
IUUC-Hsa-046372	Homo sapiens	95.28	0.00e+00	3028.00
IUUC-Lch-049786	Latimeria chalumnae	59.35	0.00e+00	1877.00
IUUC-Loc-052689	Lepisosteus oculatus	74.18	0.00e+00	2382.00
IUUC-Laf-054018	Loxodonta africana	88.59	0.00e+00	2766.00
IUUC-Mcc-055558	Macaca mulatta	95.16	0.00e+00	3029.00
IUUC-Meu-056080	Macropus eugenii	89.52	0.00e+00	1005.00
IUUC-Mga-059283	Meleagris gallopavo	82.98	0.00e+00	2588.00
IUUC-Mmr-060773	Microcebus murinus	93.91	0.00e+00	2943.00
IUUC-Mdo-062688	Monodelphis domestica	89.31	0.00e+00	2636.00
IUUC-Mmu-063997	Mus musculus	91.89	0.00e+00	2877.00
IUUC-Mlu-067599	Myotis lucifugus	94.78	0.00e+00	2975.00
IUUC-Nle-069477	Nomascus leucogenys	95.22	0.00e+00	3027.00
IUUC-Opr-070188	Ochotona princeps	82.50	0.00e+00	1793.00
IUUC-Ont-071938	Oreochromis niloticus	69.42	0.00e+00	2196.00
IUUC-Oan-073055	Ornithorhynchus anatinus	88.09	0.00e+00	2656.00
IUUC-Ocu-074302	Oryctolagus cuniculus	92.26	0.00e+00	2962.00
IUUC-Ola-086604	Oryzias latipes	66.39	0.00e+00	2107.00
IUUC-Oga-088799	Otolemur garnettii	93.51	0.00e+00	2690.00
IUUC-Oar-089629	Ovis aries	95.77	0.00e+00	2976.00
IUUC-Pan-092214	Papio anubis	96.45	0.00e+00	3029.00
IUUC-Psi-093757	Pelodiscus sinensis	83.22	0.00e+00	2538.00
IUUC-Pfo-097448	Poecilia formosa	63.31	0.00e+00	1922.00
IUUC-Pab-097984	Pongo abelii	95.34	0.00e+00	3001.00
IUUC-Pca-101061	Procavia capensis	80.51	0.00e+00	1464.00
IUUC-Pva-102306	Pteropus vampyrus	96.15	0.00e+00	2949.00
IUUC-Rno-105354	Rattus norvegicus	90.20	0.00e+00	2808.00
IUUC-Sha-106938	Sarcophilus harrisii	89.78	0.00e+00	1833.00
IUUC-Ssc-115810	Sus scrofa	94.99	0.00e+00	2982.00
IUUC-Tgu-117076	Taeniopygia guttata	82.95	0.00e+00	2546.00
IUUC-Tsy-119020	Tarsius syrichta	96.24	0.00e+00	3003.00
IUUC-Tni-120813	Tetraodon nigroviridis	67.41	0.00e+00	2123.00
IUUC-Tbe-127494	Tupaia belangeri	81.88	0.00e+00	1029.00
IUUC-Ttr-128393	Tursiops truncatus	90.25	0.00e+00	2777.00
IUUC-Vpa-130675	Vicugna pacos	83.03	0.00e+00	781.00
IUUC-Xtr-132829	Xenopus tropicalis	78.65	0.00e+00	2539.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence