iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001960

Ensembl Protein ID

ENSAMEP00000015456.1

UniProt Accession

D2HRX8; D2HRX8_AILME

Genbank Protein ID

EFB22620.1

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01152761

Gene Name

LATS2; PANDA_014787

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014668.1	ENSAMET00000016099.1	ENSAMEP00000015456.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	85.56	0.00e+00	1894.00	IUUC-Hsa-046254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KPSAQGLPVG PNSDASLATK VLGGKDAARQ 60
QQQMRATPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN RQMLQELVNA GCDQEMAGRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCAA AGACTTTTCC TGCCACAACT TATTCTGGAA ATAGCCGCCA GCGACTGCAG 60
GAGATTCGAG AGGGCTTAAA GCAGCCGTCC AAGCCTTCCG CTCAGGGGCT GCCTGTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00433--Pkinase_C

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620--P:regulation of organ growth

KEGG

aml:100477415

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003521	Anas platyrhynchos	75.16	0.00e+00	1318.00
IUUC-Aca-004995	Anolis carolinensis	72.94	0.00e+00	1579.00
IUUC-Ame-011481	Astyanax mexicanus	62.06	0.00e+00	1249.00
IUUC-Bta-012618	Bos taurus	85.71	0.00e+00	1025.00
IUUC-Cja-019430	Callithrix jacchus	84.34	0.00e+00	1804.00
IUUC-Cfa-020687	Canis familiaris	95.94	0.00e+00	2088.00
IUUC-Cpo-021985	Cavia porcellus	86.64	0.00e+00	1107.00
IUUC-Csa-023534	Chlorocebus sabaeus	97.52	0.00e+00	1013.00
IUUC-Cho-024363	Choloepus hoffmanni	82.08	0.00e+00	754.00
IUUC-Dre-027538	Danio rerio	61.85	0.00e+00	1267.00
IUUC-Dno-029126	Dasypus novemcinctus	85.99	0.00e+00	1949.00
IUUC-Dor-030172	Dipodomys ordii	82.15	0.00e+00	1562.00
IUUC-Eca-033868	Equus caballus	93.75	0.00e+00	2065.00
IUUC-Eeu-034881	Erinaceus europaeus	72.52	0.00e+00	1238.00
IUUC-Fca-036203	Felis catus	88.47	0.00e+00	1893.00
IUUC-Fal-036668	Ficedula albicollis	76.48	0.00e+00	1703.00
IUUC-Gmo-039195	Gadus morhua	85.28	0.00e+00	783.00
IUUC-Gac-041789	Gasterosteus aculeatus	61.41	0.00e+00	1180.00
IUUC-Ggo-044904	Gorilla gorilla	82.18	0.00e+00	1738.00
IUUC-Hsa-046254	Homo sapiens	85.11	0.00e+00	1744.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	84.26	0.00e+00	1593.00
IUUC-Lch-050079	Latimeria chalumnae	68.64	0.00e+00	1534.00
IUUC-Loc-052265	Lepisosteus oculatus	68.86	0.00e+00	933.00
IUUC-Laf-053806	Loxodonta africana	85.06	0.00e+00	1915.00
IUUC-Mcc-055253	Macaca mulatta	84.63	0.00e+00	1768.00
IUUC-Meu-056509	Macropus eugenii	84.40	0.00e+00	820.00
IUUC-Mga-059600	Meleagris gallopavo	76.30	0.00e+00	1724.00
IUUC-Mmr-061586	Microcebus murinus	83.82	0.00e+00	1705.00
IUUC-Mdo-062126	Monodelphis domestica	77.13	0.00e+00	1669.00
IUUC-Mmu-063164	Mus musculus	78.05	0.00e+00	1598.00
IUUC-Mpu-065992	Mustela putorius furo	97.51	0.00e+00	2192.00
IUUC-Mlu-067728	Myotis lucifugus	81.58	0.00e+00	1714.00
IUUC-Nle-069546	Nomascus leucogenys	85.60	0.00e+00	1762.00
IUUC-Opr-070872	Ochotona princeps	82.48	0.00e+00	1719.00
IUUC-Ont-072296	Oreochromis niloticus	87.02	0.00e+00	921.00
IUUC-Ocu-074068	Oryctolagus cuniculus	84.31	0.00e+00	1761.00
IUUC-Ola-086756	Oryzias latipes	59.51	0.00e+00	1186.00
IUUC-Oga-089066	Otolemur garnettii	85.47	0.00e+00	1853.00
IUUC-Oar-090416	Ovis aries	85.54	0.00e+00	1025.00
IUUC-Ptr-091247	Pan troglodytes	85.20	0.00e+00	1781.00
IUUC-Pan-092438	Papio anubis	84.81	0.00e+00	1773.00
IUUC-Psi-093920	Pelodiscus sinensis	75.90	0.00e+00	1712.00
IUUC-Pfo-096334	Poecilia formosa	85.54	0.00e+00	899.00
IUUC-Pab-098452	Pongo abelii	84.70	0.00e+00	1788.00
IUUC-Pca-101081	Procavia capensis	79.46	0.00e+00	1776.00
IUUC-Rno-105102	Rattus norvegicus	78.43	0.00e+00	1583.00
IUUC-Sha-106917	Sarcophilus harrisii	76.90	0.00e+00	1707.00
IUUC-Sar-113711	Sorex araneus	80.34	0.00e+00	1592.00
IUUC-Tgu-116553	Taeniopygia guttata	77.52	0.00e+00	1711.00
IUUC-Tru-118069	Takifugu rubripes	85.92	0.00e+00	902.00
IUUC-Tni-120617	Tetraodon nigroviridis	81.61	0.00e+00	888.00
IUUC-Ttr-129256	Tursiops truncatus	80.35	0.00e+00	1101.00
IUUC-Xtr-132593	Xenopus tropicalis	70.95	0.00e+00	1530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence