iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094349

UUCD1 version

UUC-PeM-00537

Ensembl Protein ID

ENSPMAP00000006740.1

UniProt Accession

S4RNF4; S4RNF4_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000006088.1	ENSPMAT00000006770.1	ENSPMAP00000006740.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-77	258.6	455	951

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++++ +r+++l+    +ln +       +l+ +lq lf+ l +++++a++pr++l++ +   + f+  +q
   Q: 455  TGLVNLGNTCYMNSIIQALFMTTHFRRAVLS---LSLNGS------RPLMGKLQLLFAFLAHTQRSAFEPRNFLEVSR--PPWFTPGSQ 532
           7******************************...666665......58***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk.......eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           qD++E+l++ll +++ee k        ++  + ++ + +  ++l++ +e ++k ++++l++++F+g+l ++i c++c+ vs+r+e f+d
   Q: 533  QDCSEYLKYLLTRIHEEEKTliqlktqSAGGNPQDCKRTGAEALESPKEVSEKDEERTLVEKMFGGKLLTRISCKNCRGVSERFEAFTD 621
           ******************765554443333333334444444444449999999999******************************** PP
   S: 172  lslpvpgkeetkke........................................................................... 185
           lsl++p +  ++                                                                             
   Q: 622  LSLAFPTQGVESAAkldsvqpvtsshlaneissvpnvtqhsalpsgcaqapecqevrpgphvlvggngvsvssnerppskpevvvcspd 710
           ******9987766689************************************************************************* PP
   S: 186  ........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
                   s+  +++ f ++e+l gen+yyce c+++q+ae+ + + + Pe+L+l L Rfs++ +++sr+ki ++v++p +L ls    
   Q: 711  sdtdreseSVPGLINYFLTPETLSGENRYYCEACNSLQDAERATLVAESPEYLVLTLLRFSYDMRTHSRRKILRNVHIPPSLVLSARAK 799
           *******************************************************************************9999996555 PP
   S: 267  s.....peekqke....................................kkkYeLiavvvHsG.slssGHYvayvkn............ 301
           +     +     +                                    ++ Y L++vvvHsG s++sGHY++y+++            
   Q: 800  DcscnlK-----VssgvdtddsccnaksplckkmkhseaelesdgfcdsTVPYVLTSVVVHSGmSSESGHYYSYARDcgkqrggtrrch 883
           5334440.....1455556666666666677777777778888888888**************************************** PP
   S: 302  ..........................ekgk...WllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                     e  +   Wllf+Ds+V+ ++  +v   t+    +taYvl+Y+rr
   Q: 884  rfsssnnnlmpegtaasptdeseeeeE--QgeeWLLFNDSRVSFSSFGSVSGVTSrfpkDTAYVLIYRRR 951
           *****************9999988652..2457**************99999988999*********996 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MDKILEGLLS SSHPLPVKRS VVKKVLEAAE GKLDGEQCQA MFTLATRLTL LSEDTFQRQV 60
GQQVLDAYAR CHRAQFGDFF NSELVLGMLR QGYGSLGRRD ARLLDFVQHG LRLSLSLPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG TCTGCTGAGC TCATCGCACC CGCTGCCGGT GAAGCGCAGC 60
GTGGTGAAGA AGGTCCTTGA AGCGGCCGAG GGCAAACTGG ATGGAGAGCA ATGCCAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	52.87	0.00e+00	944.00
IUUC-Apl-004121	Anas platyrhynchos	46.98	0.00e+00	725.00
IUUC-Aca-004556	Anolis carolinensis	50.88	0.00e+00	848.00
IUUC-Ame-010616	Astyanax mexicanus	51.97	0.00e+00	941.00
IUUC-Bta-013544	Bos taurus	52.92	0.00e+00	940.00
IUUC-Cja-018745	Callithrix jacchus	51.79	0.00e+00	956.00
IUUC-Cfa-020434	Canis familiaris	53.68	0.00e+00	936.00
IUUC-Cpo-021666	Cavia porcellus	53.22	0.00e+00	918.00
IUUC-Csa-023965	Chlorocebus sabaeus	53.21	0.00e+00	1000.00
IUUC-Cho-024809	Choloepus hoffmanni	45.85	5.00e-173	600.00
IUUC-Cin-025604	Ciona intestinalis	30.32	4.00e-43	167.00
IUUC-Csv-026333	Ciona savignyi	42.44	1.00e-30	125.00
IUUC-Dre-028338	Danio rerio	51.86	0.00e+00	964.00
IUUC-Dno-029372	Dasypus novemcinctus	52.95	0.00e+00	971.00
IUUC-Dor-030752	Dipodomys ordii	51.58	4.00e-172	597.00
IUUC-Dme-031871	Drosophila melanogaster	26.21	4.00e-47	181.00
IUUC-Ete-032588	Echinops telfairi	47.12	2.00e-163	568.00
IUUC-Eca-034416	Equus caballus	52.83	0.00e+00	984.00
IUUC-Eeu-035120	Erinaceus europaeus	40.83	7.00e-114	403.00
IUUC-Fca-036137	Felis catus	53.55	0.00e+00	1003.00
IUUC-Fal-037297	Ficedula albicollis	52.30	0.00e+00	907.00
IUUC-Gmo-038727	Gadus morhua	54.74	0.00e+00	800.00
IUUC-Gga-041091	Gallus gallus	53.47	0.00e+00	902.00
IUUC-Gac-042082	Gasterosteus aculeatus	50.24	0.00e+00	862.00
IUUC-Ggo-045376	Gorilla gorilla	50.15	0.00e+00	890.00
IUUC-Hsa-046444	Homo sapiens	53.12	0.00e+00	986.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	53.31	0.00e+00	994.00
IUUC-Lch-050500	Latimeria chalumnae	52.24	0.00e+00	945.00
IUUC-Loc-052625	Lepisosteus oculatus	51.94	0.00e+00	975.00
IUUC-Laf-053689	Loxodonta africana	52.92	0.00e+00	978.00
IUUC-Mcc-055286	Macaca mulatta	52.96	0.00e+00	981.00
IUUC-Meu-056906	Macropus eugenii	50.24	5.00e-180	623.00
IUUC-Mga-059595	Meleagris gallopavo	45.71	0.00e+00	815.00
IUUC-Mmr-061397	Microcebus murinus	53.31	0.00e+00	948.00
IUUC-Mdo-062833	Monodelphis domestica	52.24	0.00e+00	989.00
IUUC-Mmu-063157	Mus musculus	53.21	0.00e+00	941.00
IUUC-Mpu-066434	Mustela putorius furo	53.08	0.00e+00	996.00
IUUC-Mlu-068178	Myotis lucifugus	52.76	0.00e+00	923.00
IUUC-Nle-070153	Nomascus leucogenys	53.21	0.00e+00	924.00
IUUC-Opr-070454	Ochotona princeps	43.18	1.00e-64	239.00
IUUC-Ont-072330	Oreochromis niloticus	51.89	0.00e+00	944.00
IUUC-Oan-072709	Ornithorhynchus anatinus	51.96	0.00e+00	728.00
IUUC-Ocu-074832	Oryctolagus cuniculus	52.73	0.00e+00	941.00
IUUC-Opu-083257	Oryza punctata	30.50	5.00e-13	69.30
IUUC-Ola-087003	Oryzias latipes	46.29	4.00e-28	115.00
IUUC-Oga-088517	Otolemur garnettii	51.41	0.00e+00	911.00
IUUC-Oar-089472	Ovis aries	50.97	0.00e+00	872.00
IUUC-Ptr-090996	Pan troglodytes	53.26	0.00e+00	987.00
IUUC-Pan-091837	Papio anubis	51.77	0.00e+00	949.00
IUUC-Psi-093707	Pelodiscus sinensis	45.93	0.00e+00	786.00
IUUC-Pfo-097193	Poecilia formosa	51.80	0.00e+00	866.00
IUUC-Pab-098710	Pongo abelii	53.04	0.00e+00	991.00
IUUC-Pca-100794	Procavia capensis	46.45	0.00e+00	796.00
IUUC-Pva-102722	Pteropus vampyrus	53.28	0.00e+00	982.00
IUUC-Rno-105743	Rattus norvegicus	53.97	0.00e+00	939.00
IUUC-Sha-106563	Sarcophilus harrisii	52.56	0.00e+00	781.00
IUUC-Sar-113533	Sorex araneus	47.01	0.00e+00	806.00
IUUC-Ssc-116259	Sus scrofa	63.35	0.00e+00	646.00
IUUC-Tgu-117024	Taeniopygia guttata	46.46	0.00e+00	824.00
IUUC-Tru-118623	Takifugu rubripes	49.76	0.00e+00	868.00
IUUC-Tsy-119250	Tarsius syrichta	52.47	0.00e+00	732.00
IUUC-Tni-120441	Tetraodon nigroviridis	46.20	0.00e+00	798.00
IUUC-Tbe-127936	Tupaia belangeri	44.42	0.00e+00	703.00
IUUC-Ttr-128211	Tursiops truncatus	49.52	5.00e-162	563.00
IUUC-Vpa-130303	Vicugna pacos	63.72	0.00e+00	696.00
IUUC-Xtr-132773	Xenopus tropicalis	50.48	0.00e+00	920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence