iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090996

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin specific peptidase 38

Genbank Nucleotide ID

AACZ03032293

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016470.5	ENSPTRT00000030613.5	ENSPTRP00000028273.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.30e-83	278.5	445	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e  e ++++l++         +  ++   +k+li+++F+g+l+++i+cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkvQASHKPSEILECSETSLQEVaskaavltETPRTSDGEKTLIEKMFGGKLRTHIRCLNCRSTSQKVE 611
           *****************95577788888888888888888888888999988888888999**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ ++                                                                        
   Q: 612  AFTDLSLAFCPSSSLENMsvqdpasspsiqdgglmqasvpgpseepvvynpttaaficdslvnektigsppnefycsentsvpnesnki 700
           *********9999776669********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++p  
   Q: 701  lvnkdvpqkpgsettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPMV 789
           ***************************************************************************************99 PP
   S: 259  Ldlspfcts...............................peekqkekkkYeLiavvvHsG.slssGHYvayvkn.............. 301
           L+l    ++                               +e + ++ + Y L++vvvHsG s++sGHY++y++n              
   Q: 790  LELPVKRITsfsslseswsvdvdftdlsenlakklkpsgtDEASCTKLVPYLLSSVVVHSGiSSESGHYYSYARNitstdssyqmyhqs 878
           999854444356667777777777777777777777666644445559***************************************** PP
   S: 302  ..............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                          +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 879  ealalassqshllgrdspnavfeqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 949
           ******9999999999999999988865544555*******************999************986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLH QGYHSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCCCAGCA CTCTCCGTGA CAGCGCCTCC TGACTCAGCC CAGGACCGGC TTCTTCTCAC 60
GACCTGCTGG AGACTGGACG CCCANNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	92.64	0.00e+00	1852.00
IUUC-Apl-003435	Anas platyrhynchos	75.80	0.00e+00	1260.00
IUUC-Aca-004556	Anolis carolinensis	71.07	0.00e+00	1305.00
IUUC-Ame-010616	Astyanax mexicanus	62.52	0.00e+00	1239.00
IUUC-Bta-013544	Bos taurus	92.51	0.00e+00	1819.00
IUUC-Cja-018745	Callithrix jacchus	94.07	0.00e+00	1906.00
IUUC-Cfa-020434	Canis familiaris	89.16	0.00e+00	1781.00
IUUC-Cpo-021666	Cavia porcellus	91.46	0.00e+00	1780.00
IUUC-Csa-023965	Chlorocebus sabaeus	97.70	0.00e+00	2032.00
IUUC-Cho-024809	Choloepus hoffmanni	83.74	0.00e+00	1276.00
IUUC-Cin-025604	Ciona intestinalis	37.39	6.00e-41	160.00
IUUC-Csv-026333	Ciona savignyi	44.25	3.00e-32	131.00
IUUC-Dre-028338	Danio rerio	63.18	0.00e+00	1256.00
IUUC-Dno-029372	Dasypus novemcinctus	91.94	0.00e+00	1856.00
IUUC-Dor-030752	Dipodomys ordii	88.95	0.00e+00	1238.00
IUUC-Dme-031871	Drosophila melanogaster	34.45	6.00e-43	169.00
IUUC-Ete-032588	Echinops telfairi	79.74	0.00e+00	1132.00
IUUC-Eca-034416	Equus caballus	93.86	0.00e+00	1936.00
IUUC-Eeu-035132	Erinaceus europaeus	73.76	0.00e+00	1397.00
IUUC-Fca-036137	Felis catus	93.19	0.00e+00	1892.00
IUUC-Fal-037297	Ficedula albicollis	75.21	0.00e+00	1440.00
IUUC-Gmo-038727	Gadus morhua	66.92	0.00e+00	1028.00
IUUC-Gga-041091	Gallus gallus	73.73	0.00e+00	1397.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.90	0.00e+00	1144.00
IUUC-Ggo-045376	Gorilla gorilla	94.55	0.00e+00	1884.00
IUUC-Hsa-046444	Homo sapiens	99.62	0.00e+00	2027.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	92.90	0.00e+00	1904.00
IUUC-Lch-050500	Latimeria chalumnae	71.99	0.00e+00	1433.00
IUUC-Loc-052625	Lepisosteus oculatus	64.68	0.00e+00	1306.00
IUUC-Laf-053689	Loxodonta africana	92.88	0.00e+00	1881.00
IUUC-Mcc-055286	Macaca mulatta	97.79	0.00e+00	1991.00
IUUC-Meu-056906	Macropus eugenii	50.53	0.00e+00	657.00
IUUC-Mga-059905	Meleagris gallopavo	73.90	0.00e+00	1227.00
IUUC-Mmr-061397	Microcebus murinus	94.91	0.00e+00	1909.00
IUUC-Mdo-062833	Monodelphis domestica	85.74	0.00e+00	1788.00
IUUC-Mmu-063157	Mus musculus	89.92	0.00e+00	1820.00
IUUC-Mpu-066434	Mustela putorius furo	93.76	0.00e+00	1915.00
IUUC-Mlu-068178	Myotis lucifugus	91.21	0.00e+00	1800.00
IUUC-Nle-070153	Nomascus leucogenys	97.89	0.00e+00	1942.00
IUUC-Opr-070454	Ochotona princeps	44.86	2.00e-69	257.00
IUUC-Ont-072330	Oreochromis niloticus	63.59	0.00e+00	1249.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.05	0.00e+00	1281.00
IUUC-Ocu-074832	Oryctolagus cuniculus	93.86	0.00e+00	1894.00
IUUC-Ola-087003	Oryzias latipes	55.17	3.00e-48	184.00
IUUC-Oga-088517	Otolemur garnettii	89.88	0.00e+00	1797.00
IUUC-Oar-089472	Ovis aries	88.87	0.00e+00	1748.00
IUUC-Pan-091837	Papio anubis	95.71	0.00e+00	1978.00
IUUC-Psi-093236	Pelodiscus sinensis	76.12	0.00e+00	1160.00
IUUC-Pma-094349	Petromyzon marinus	53.24	0.00e+00	983.00
IUUC-Pfo-097193	Poecilia formosa	61.97	0.00e+00	1165.00
IUUC-Pab-098710	Pongo abelii	98.46	0.00e+00	2025.00
IUUC-Pca-100794	Procavia capensis	81.69	0.00e+00	1640.00
IUUC-Pva-102722	Pteropus vampyrus	92.81	0.00e+00	1893.00
IUUC-Rno-105743	Rattus norvegicus	89.35	0.00e+00	1785.00
IUUC-Sha-106563	Sarcophilus harrisii	84.68	0.00e+00	1446.00
IUUC-Sar-113533	Sorex araneus	77.35	0.00e+00	1556.00
IUUC-Ssc-116259	Sus scrofa	83.56	0.00e+00	1580.00
IUUC-Tgu-117475	Taeniopygia guttata	75.58	0.00e+00	1313.00
IUUC-Tru-118623	Takifugu rubripes	63.00	0.00e+00	1158.00
IUUC-Tsy-119250	Tarsius syrichta	92.75	0.00e+00	1487.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.59	0.00e+00	1077.00
IUUC-Tbe-127936	Tupaia belangeri	81.09	0.00e+00	1541.00
IUUC-Ttr-128483	Tursiops truncatus	80.40	0.00e+00	1408.00
IUUC-Vpa-130303	Vicugna pacos	97.75	0.00e+00	1076.00
IUUC-Xtr-132773	Xenopus tropicalis	72.27	0.00e+00	1415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence