iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106563

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01215797

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011121.1	ENSSHAT00000013106.1	ENSSHAP00000013000.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-83	279.2	268	775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+ +l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 268  TGLINLGNTCYMNSVIQALFMATDFRRHVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 345
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.............aeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           qD++E+l+flld+l+ee      k  ++++ +++  +++              +   ++ ++k+li+++F+g+l+++i cl+c+++s++
   Q: 346  QDCSEYLRFLLDRLHEEERT--LKALSSLKPSESMGSDEAslqevtnktapytEIPYTNDSEKTLIEKMFGGKLQTNIHCLNCRSTSQK 432
           *****************933..44444444444334333333333667766656666777778************************** PP
   S: 166  eepfldlslpvpgkeetkke..................................................................... 185
           ee f+dlsl++  +++++++                                                                     
   Q: 433  EEAFTDLSLAFCPSSSMENLsfqgpscspkvqddfvvqaslvtagspeesafchpvppgfgsetvmdeaaldnlpselpctentlvsne 521
           ************999887779******************************************************************** PP
   S: 186  ....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
                               s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++ + Pe+Lil L Rfs++++ + r+ki ++v+
   Q: 522  pckiqinrgvsqkpggentpSVTDLLNYFLAPEILNGDNRYYCENCASLQNAEKTMQIMEEPEYLILTLLRFSYDQKCHIRRKILDNVS 610
           ***************************************************************************************** PP
   S: 255  fpleLdlspfctspeekqke................................kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           +pl L+l    t+++ ++ +                                ++ Y L++vvvHsG s++sGHY++y++n         
   Q: 611  LPLVLELPVKRTNSSLTSLSeswsvdvdftdtgenlakklkssgtdeaccpkRVPYLLSSVVVHSGiSSESGHYYSYARNitgsdssfq 699
           **999998655553333333566666666666667777777777777888889************************************ PP
   S: 302  ...................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                               +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 700  lchqsetlalaspqghllggeipsavieqdlenneMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 775
           ***********9999999999999999988866544555*******************999************986 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

FQCASGQEKE LREYVARVTK VSHLLQNIWK AEPATLLPSL QEVFASISST DASFEPSVAL 60
ASLVQHIPLQ MITVLIRSLT TDPNVKDASM TQALCRMIDW LSWPLAQHVE TWVIALLKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN TTCCAGTGCG CCTCGGGCCA GGAGAAGGAG CTGCGCGAGT ACGTGGCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	83.03	0.00e+00	1342.00
IUUC-Apl-003435	Anas platyrhynchos	78.34	0.00e+00	1209.00
IUUC-Aca-004556	Anolis carolinensis	74.54	0.00e+00	1165.00
IUUC-Ame-010616	Astyanax mexicanus	61.94	0.00e+00	1021.00
IUUC-Bta-013544	Bos taurus	84.79	0.00e+00	1360.00
IUUC-Cja-018745	Callithrix jacchus	82.25	0.00e+00	1349.00
IUUC-Cfa-020434	Canis familiaris	83.29	0.00e+00	1362.00
IUUC-Cpo-021666	Cavia porcellus	83.66	0.00e+00	1300.00
IUUC-Csa-023965	Chlorocebus sabaeus	85.14	0.00e+00	1448.00
IUUC-Cho-024809	Choloepus hoffmanni	77.95	0.00e+00	1186.00
IUUC-Csv-026333	Ciona savignyi	44.00	9.00e-33	133.00
IUUC-Dre-028338	Danio rerio	61.55	0.00e+00	1004.00
IUUC-Dno-029372	Dasypus novemcinctus	86.18	0.00e+00	1409.00
IUUC-Dor-030752	Dipodomys ordii	81.09	0.00e+00	1128.00
IUUC-Dme-031871	Drosophila melanogaster	29.68	4.00e-45	176.00
IUUC-Ete-032588	Echinops telfairi	74.51	0.00e+00	1082.00
IUUC-Eca-034416	Equus caballus	84.91	0.00e+00	1433.00
IUUC-Eeu-035132	Erinaceus europaeus	64.87	0.00e+00	1015.00
IUUC-Fca-036137	Felis catus	84.45	0.00e+00	1415.00
IUUC-Fal-037297	Ficedula albicollis	78.74	0.00e+00	1252.00
IUUC-Gmo-038727	Gadus morhua	65.97	0.00e+00	800.00
IUUC-Gga-041091	Gallus gallus	75.89	0.00e+00	1168.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.02	0.00e+00	941.00
IUUC-Ggo-045376	Gorilla gorilla	79.47	0.00e+00	1283.00
IUUC-Hsa-046444	Homo sapiens	85.14	0.00e+00	1418.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	83.87	0.00e+00	1396.00
IUUC-Lch-050500	Latimeria chalumnae	70.61	0.00e+00	1184.00
IUUC-Loc-052625	Lepisosteus oculatus	64.34	0.00e+00	1052.00
IUUC-Laf-053689	Loxodonta africana	85.88	0.00e+00	1432.00
IUUC-Mcc-055286	Macaca mulatta	84.56	0.00e+00	1395.00
IUUC-Meu-056437	Macropus eugenii	82.76	5.00e-152	531.00
IUUC-Mga-059905	Meleagris gallopavo	76.04	0.00e+00	1202.00
IUUC-Mmr-061397	Microcebus murinus	85.37	0.00e+00	1395.00
IUUC-Mdo-062833	Monodelphis domestica	96.77	0.00e+00	1680.00
IUUC-Mmu-063157	Mus musculus	82.14	0.00e+00	1342.00
IUUC-Mpu-066434	Mustela putorius furo	84.10	0.00e+00	1399.00
IUUC-Mlu-068178	Myotis lucifugus	83.73	0.00e+00	1335.00
IUUC-Nle-070153	Nomascus leucogenys	84.22	0.00e+00	1342.00
IUUC-Ont-072330	Oreochromis niloticus	62.93	0.00e+00	1028.00
IUUC-Oan-072709	Ornithorhynchus anatinus	86.69	0.00e+00	1418.00
IUUC-Ocu-074832	Oryctolagus cuniculus	84.56	0.00e+00	1385.00
IUUC-Ola-087003	Oryzias latipes	54.19	2.00e-48	184.00
IUUC-Oga-088517	Otolemur garnettii	79.73	0.00e+00	1290.00
IUUC-Oar-089472	Ovis aries	80.65	0.00e+00	1287.00
IUUC-Ptr-090996	Pan troglodytes	84.68	0.00e+00	1411.00
IUUC-Pan-091837	Papio anubis	82.40	0.00e+00	1376.00
IUUC-Psi-093236	Pelodiscus sinensis	80.18	0.00e+00	1238.00
IUUC-Pma-094349	Petromyzon marinus	52.97	0.00e+00	770.00
IUUC-Pfo-097193	Poecilia formosa	61.15	0.00e+00	921.00
IUUC-Pab-098710	Pongo abelii	84.45	0.00e+00	1415.00
IUUC-Pca-100794	Procavia capensis	72.96	0.00e+00	1177.00
IUUC-Pva-102722	Pteropus vampyrus	83.31	0.00e+00	1384.00
IUUC-Rno-105743	Rattus norvegicus	81.91	0.00e+00	1330.00
IUUC-Sar-113533	Sorex araneus	70.62	0.00e+00	1134.00
IUUC-Ssc-116259	Sus scrofa	74.11	0.00e+00	1109.00
IUUC-Tgu-117475	Taeniopygia guttata	78.16	0.00e+00	1257.00
IUUC-Tru-118623	Takifugu rubripes	62.36	0.00e+00	921.00
IUUC-Tsy-119250	Tarsius syrichta	84.21	0.00e+00	1352.00
IUUC-Tni-120441	Tetraodon nigroviridis	57.11	0.00e+00	818.00
IUUC-Tbe-127936	Tupaia belangeri	71.31	0.00e+00	1082.00
IUUC-Ttr-128483	Tursiops truncatus	70.97	0.00e+00	1117.00
IUUC-Vpa-130303	Vicugna pacos	96.36	0.00e+00	715.00
IUUC-Xtr-132773	Xenopus tropicalis	69.99	0.00e+00	1131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence