iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049634

Ensembl Protein ID

ENSLACP00000017186.2

UniProt Accession

H3B5L5; H3B5L5_LATCH

Genbank Protein ID

ENSLACP00000017186

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01018743

Gene Name

RACK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000015141.2	ENSLACT00000017312.2	ENSLACP00000017186.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-40	135.9	103	133
UBD/Beta-Prp	1.80e-51	175.3	10	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH+ +v ++af  +++ +vsGs+D+tik+W+
   Q: 103  GHSKDVLSVAFsaDNRQIVSGSRDKTIKLWN 133
           8***********64499*************9 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv 87
           tlkgh+  v +  +  ++ ++++++srd++i+ w++t+  +      r l gh  +v++v +s+dg++ ++gs D ++++wdl  g ++
   Q: 10   TLKGHNGWVTQIATTPQFPDMILSASRDKSIIMWKLTRDETnygipQRALRGHAHFVSDVVISSDGQFALSGSWDSNLRLWDLTLGITT 98
           7788887776655559999*******************999************************************************ PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrt 174
           + + gh+++vls++fs+++  +vsGs+d+ti++w++    ++   ++gh+++ +cv+++p++   ++vs++ Dr v++W+l++ kl + 
   Q: 99   RQFVGHSKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWASCVRFSPNSnnPIIVSCGWDRLVKVWNLANCKLKTN 187
           **********************************7765555544899************9986469***************77777666 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
             g h ++ + ++++++g  ++sg++dg+  lwdl +g+ ++tl g  d ++ + fs  + + ++++  +si+iWdl+ +
   Q: 188  HIG-HVGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFS-PNRYWLCAATGPSIKIWDLEGK 264
           676.****************************************996.577878888.7888899999********9865 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKSI IMWKLTRDET NYGIPQRALR 60
GHAHFVSDVV ISSDGQFALS GSWDSNLRLW DLTLGITTRQ FVGHSKDVLS VAFSADNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGTAATTA CAACTAAAGT TAAACAGATC TGTCCTGGGC CATAGCATAA CTTTCCACTC 60
ACAGCCAAAC CGTGCATCTA GTTGCTCACA TTTTTCAAGT GTATGTTTCT CCCTCCTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001525--P:angiogenesis
GO:0060027--P:convergent extension involved in gastrulation
GO:0030178--P:negative regulation of Wnt signaling pathway
GO:2000543--P:positive regulation of gastrulation
GO:0051302--P:regulation of cell division
GO:2000114--P:regulation of establishment of cell polarity
GO:0032880--P:regulation of protein localization

KEGG

lcm:102346429

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	64.44	4.00e-102	363.00
IUUC-Aml-001935	Ailuropoda melanoleuca	94.32	0.00e+00	628.00
IUUC-Atr-002694	Amborella trichopoda	66.77	3.00e-123	434.00
IUUC-Apl-003918	Anas platyrhynchos	93.59	2.00e-159	554.00
IUUC-Aca-004869	Anolis carolinensis	94.32	0.00e+00	628.00
IUUC-Aly-005671	Arabidopsis lyrata	64.20	6.00e-123	433.00
IUUC-Ath-007584	Arabidopsis thaliana	63.89	2.00e-122	431.00
IUUC-Ago-007720	Ashbya gossypii	54.63	6.00e-100	357.00
IUUC-Acl-008156	Aspergillus clavatus	71.47	2.00e-136	478.00
IUUC-Afl-008684	Aspergillus flavus	70.51	2.00e-135	474.00
IUUC-Afu-008867	Aspergillus fumigatus	72.44	2.00e-138	484.00
IUUC-Ani-009221	Aspergillus nidulans	71.79	5.00e-137	480.00
IUUC-Ang-009843	Aspergillus niger	70.51	5.00e-135	473.00
IUUC-Aor-010193	Aspergillus oryzae	70.51	2.00e-135	474.00
IUUC-Ate-010420	Aspergillus terreus	72.44	9.00e-124	436.00
IUUC-Ame-010884	Astyanax mexicanus	94.01	0.00e+00	627.00
IUUC-Bgr-012064	Blumeria graminis	68.59	1.00e-132	465.00
IUUC-Bta-013357	Bos taurus	94.32	0.00e+00	628.00
IUUC-Bci-013862	Botrytis cinerea	69.87	5.00e-135	473.00
IUUC-Bdi-014690	Brachypodium distachyon	61.16	9.00e-112	396.00
IUUC-Bol-016231	Brassica oleracea	65.02	2.00e-124	438.00
IUUC-Bra-016879	Brassica rapa	64.60	4.00e-123	433.00
IUUC-Cel-018335	Caenorhabditis elegans	68.75	2.00e-122	431.00
IUUC-Cja-019914	Callithrix jacchus	94.32	0.00e+00	628.00
IUUC-Cfa-020755	Canis familiaris	94.32	0.00e+00	628.00
IUUC-Cpo-022377	Cavia porcellus	94.32	0.00e+00	630.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	73.65	9.00e-135	472.00
IUUC-Csa-023025	Chlorocebus sabaeus	94.32	0.00e+00	627.00
IUUC-Cin-025647	Ciona intestinalis	76.75	8.00e-146	509.00
IUUC-Csv-026027	Ciona savignyi	77.07	2.00e-144	504.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	72.08	2.00e-125	441.00
IUUC-Cne-026930	Cryptococcus neoformans	69.87	7.00e-135	473.00
IUUC-Cme-027251	Cyanidioschyzon merolae	63.46	2.00e-120	424.00
IUUC-Dre-028669	Danio rerio	93.06	1.00e-179	621.00
IUUC-Dno-029470	Dasypus novemcinctus	79.31	4.00e-144	504.00
IUUC-Dor-031098	Dipodomys ordii	85.17	2.00e-145	508.00
IUUC-Dse-031255	Dothistroma septosporum	70.83	9.00e-136	476.00
IUUC-Dme-032118	Drosophila melanogaster	77.14	9.00e-147	512.00
IUUC-Ete-033182	Echinops telfairi	78.03	5.00e-101	360.00
IUUC-Eca-033296	Equus caballus	94.67	1.00e-84	304.00
IUUC-Eeu-034771	Erinaceus europaeus	89.91	6.00e-171	592.00
IUUC-Fca-036315	Felis catus	94.32	0.00e+00	628.00
IUUC-Fal-036990	Ficedula albicollis	92.78	2.00e-100	358.00
IUUC-Fox-037702	Fusarium oxysporum	71.47	2.00e-137	481.00
IUUC-Fso-038384	Fusarium solani	71.15	8.00e-137	479.00
IUUC-Gmo-039630	Gadus morhua	91.88	1.00e-172	598.00
IUUC-Ggr-039985	Gaeumannomyces graminis	70.19	5.00e-136	476.00
IUUC-Gga-040540	Gallus gallus	94.32	0.00e+00	628.00
IUUC-Gac-041316	Gasterosteus aculeatus	91.96	9.00e-175	605.00
IUUC-Gma-042872	Glycine max	64.60	2.00e-122	431.00
IUUC-Ggo-045253	Gorilla gorilla	94.32	0.00e+00	628.00
IUUC-Hsa-046809	Homo sapiens	94.32	0.00e+00	628.00
IUUC-Hvu-047683	Hordeum vulgare	62.01	2.00e-113	401.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	94.32	0.00e+00	628.00
IUUC-Kpa-049214	Komagataella pastoris	56.13	3.00e-97	347.00
IUUC-Lpe-050763	Leersia perrieri	61.47	2.00e-111	395.00
IUUC-Loc-052163	Lepisosteus oculatus	95.27	0.00e+00	630.00
IUUC-Lma-053113	Leptosphaeria maculans	71.15	3.00e-137	481.00
IUUC-Laf-054422	Loxodonta africana	94.32	0.00e+00	628.00
IUUC-Mcc-055348	Macaca mulatta	94.32	0.00e+00	628.00
IUUC-Meu-056543	Macropus eugenii	94.32	0.00e+00	629.00
IUUC-Mor-057107	Magnaporthe oryzae	70.19	1.00e-136	478.00
IUUC-Mpo-057487	Magnaporthe poae	70.51	1.00e-136	478.00
IUUC-Mtr-058808	Medicago truncatula	64.91	4.00e-123	434.00
IUUC-Mla-058909	Melampsora laricipopulina	71.88	8.00e-138	482.00
IUUC-Mga-059387	Meleagris gallopavo	94.32	0.00e+00	628.00
IUUC-Mvi-060392	Microbotryum violaceum	67.63	4.00e-132	463.00
IUUC-Mmr-061141	Microcebus murinus	84.08	9.00e-134	469.00
IUUC-Mdo-062932	Monodelphis domestica	94.32	0.00e+00	628.00
IUUC-Mmu-064132	Mus musculus	94.32	0.00e+00	628.00
IUUC-Mac-064447	Musa acuminata	60.19	2.00e-107	382.00
IUUC-Mpu-066721	Mustela putorius furo	93.38	3.00e-178	617.00
IUUC-Mlu-068221	Myotis lucifugus	92.43	3.00e-172	597.00
IUUC-Nfi-068344	Neosartorya fischeri	72.44	3.00e-138	484.00
IUUC-Ncr-068722	Neurospora crassa	70.19	3.00e-135	474.00
IUUC-Nle-069865	Nomascus leucogenys	94.32	0.00e+00	628.00
IUUC-Opr-071100	Ochotona princeps	79.81	2.00e-145	508.00
IUUC-Ont-072287	Oreochromis niloticus	93.38	0.00e+00	625.00
IUUC-Oan-072788	Ornithorhynchus anatinus	94.32	0.00e+00	628.00
IUUC-Ocu-073844	Oryctolagus cuniculus	91.80	6.00e-175	606.00
IUUC-Oba-075981	Oryza barthii	59.63	6.00e-102	363.00
IUUC-Obr-076099	Oryza brachyantha	60.86	2.00e-111	395.00
IUUC-Ogl-077804	Oryza glaberrima	61.77	9.00e-113	399.00
IUUC-Ogu-078035	Oryza glumaepatula	62.77	3.00e-113	401.00
IUUC-Oin-079327	Oryza indica	62.77	3.00e-113	401.00
IUUC-Olo-081084	Oryza longistaminata	62.77	3.00e-113	401.00
IUUC-Ome-081366	Oryza meridionalis	62.08	4.00e-113	400.00
IUUC-Oni-082682	Oryza nivara	62.08	4.00e-113	400.00
IUUC-Opu-084010	Oryza punctata	61.77	2.00e-113	402.00
IUUC-Oru-084358	Oryza rufipogon	62.08	4.00e-113	400.00
IUUC-Osa-085296	Oryza sativa	62.08	4.00e-113	400.00
IUUC-Ola-086400	Oryzias latipes	93.69	0.00e+00	627.00
IUUC-Olu-087817	Ostreococcus lucimarinus	72.64	3.00e-137	480.00
IUUC-Oga-088811	Otolemur garnettii	94.32	0.00e+00	628.00
IUUC-Oar-089962	Ovis aries	94.32	0.00e+00	628.00
IUUC-Ptr-091340	Pan troglodytes	94.32	0.00e+00	628.00
IUUC-Pan-091946	Papio anubis	94.32	0.00e+00	627.00
IUUC-Pma-094535	Petromyzon marinus	93.06	4.00e-179	619.00
IUUC-Pno-095100	Phaeosphaeria nodorum	72.64	3.00e-95	340.00
IUUC-Ppa-095752	Physcomitrella patens	74.44	3.00e-137	480.00
IUUC-Pfo-097311	Poecilia formosa	94.32	0.00e+00	627.00
IUUC-Pab-097863	Pongo abelii	94.32	0.00e+00	629.00
IUUC-Pop-099345	Populus trichocarpa	66.25	6.00e-126	443.00
IUUC-Pca-100594	Procavia capensis	93.69	2.00e-180	624.00
IUUC-Ppe-101743	Prunus persica	64.51	2.00e-122	431.00
IUUC-Pva-102746	Pteropus vampyrus	80.13	4.00e-145	507.00
IUUC-Pgr-103375	Puccinia graminis	54.63	2.00e-94	338.00
IUUC-Ptt-103839	Puccinia triticina	71.57	5.00e-136	476.00
IUUC-Pte-104026	Pyrenophora teres	71.15	3.00e-137	481.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	71.15	3.00e-137	481.00
IUUC-Rno-104964	Rattus norvegicus	94.32	0.00e+00	628.00
IUUC-Sce-106224	Saccharomyces cerevisiae	52.55	8.00e-95	340.00
IUUC-Sha-107409	Sarcophilus harrisii	94.32	0.00e+00	628.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	64.86	3.00e-125	440.00
IUUC-Spo-108297	Schizosaccharomyces pombe	63.58	4.00e-122	430.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	69.87	5.00e-135	473.00
IUUC-Smo-109017	Selaginella moellendorffii	68.99	1.00e-125	442.00
IUUC-Sit-110060	Setaria italica	63.38	5.00e-116	410.00
IUUC-Sly-111496	Solanum lycopersicum	67.19	4.00e-124	437.00
IUUC-Stu-112757	Solanum tuberosum	65.62	3.00e-120	424.00
IUUC-Sar-113173	Sorex araneus	94.32	0.00e+00	628.00
IUUC-Sbi-114681	Sorghum bicolor	63.38	4.00e-115	407.00
IUUC-Sre-115107	Sporisorium reilianum	67.95	8.00e-135	473.00
IUUC-Ssc-116218	Sus scrofa	89.91	5.00e-173	599.00
IUUC-Tru-118202	Takifugu rubripes	93.06	3.00e-178	617.00
IUUC-Tni-120260	Tetraodon nigroviridis	92.11	2.00e-176	610.00
IUUC-Tca-120951	Theobroma cacao	64.91	4.00e-124	437.00
IUUC-Tre-121961	Trichoderma reesei	71.47	9.00e-138	482.00
IUUC-Tvi-122447	Trichoderma virens	71.15	9.00e-137	479.00
IUUC-Tae-122791	Triticum aestivum	61.70	1.00e-112	399.00
IUUC-Tur-126335	Triticum urartu	66.67	1.00e-102	365.00
IUUC-Tme-127105	Tuber melanosporum	67.64	1.00e-124	438.00
IUUC-Tbe-128021	Tupaia belangeri	77.72	4.00e-85	306.00
IUUC-Ttr-128637	Tursiops truncatus	82.97	3.00e-155	540.00
IUUC-Uma-129634	Ustilago maydis	68.91	1.00e-135	475.00
IUUC-Vda-129923	Verticillium dahliae	70.51	4.00e-136	477.00
IUUC-Vpa-130410	Vicugna pacos	73.36	8.00e-108	382.00
IUUC-Vvi-131115	Vitis vinifera	64.81	4.00e-124	437.00
IUUC-Xtr-132105	Xenopus tropicalis	92.74	4.00e-180	623.00
IUUC-Xma-133875	Xiphophorus maculatus	94.32	0.00e+00	627.00
IUUC-Yli-134624	Yarrowia lipolytica	59.49	2.00e-117	415.00
IUUC-Zma-134711	Zea mays	62.46	7.00e-114	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence