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Tag Content
iUUCD ID IUUC-Mcc-055772
Ensembl Protein ID ENSMMUP00000016010.3
UniProt Accession F6VN46; F6VN46_MACMU
Genbank Protein ID ENSMMUP00000016010
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03026194
Gene Name NOD2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000012207.3 ENSMMUT00000057178.1 ENSMMUP00000046927.1
ENSMMUG00000012207.3 ENSMMUT00000017096.3 ENSMMUP00000016010.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/CARD 3.80e-22 79.7 203 255
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaa 55
    +e+rl+++t+++r+r+lLd+++v++++l++fll++++el+++ a + +++++
   Q: 203 DEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCR 255
    8*************************************************997 PP
   

Organism Macaca mulatta
Protein Sequence
(Fasta)
MPTPFHFRFF EALHQPLSTD PTTIAELTML RDFLSCSEIL PGLEAPGGLL ALKFPEPTAG 60
CEMCSQEAFQ AQRSQLVELL VSGSLEGFES VLDWLLSWEV LSWEDYEGIH LLGQPLSHLA 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mcc-055772|UBD,CARD|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCCTGCTC CCCAAGCCTA ATGGGCTTTG ATGGGGGAAG AGGGGGTGGT CCAGTCTCTC 60
CCGATGAGGA GGAAAGAGCA AGTGTCCTCC TTGGACATTT TCTGGGTAAG AGGAGCAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mcc-055772|UBD,CARD|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS51450--LRR
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response
GO:0042981--P:regulation of apoptotic process

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001822 Ailuropoda melanoleuca 81.24 0.00e+00 1480.00
IUUC-Ame-011021 Astyanax mexicanus 45.97 0.00e+00 872.00
IUUC-Bta-013241 Bos taurus 81.54 0.00e+00 1619.00
IUUC-Cja-019633 Callithrix jacchus 90.77 0.00e+00 1373.00
IUUC-Cfa-020039 Canis familiaris 83.22 0.00e+00 1620.00
IUUC-Cpo-022337 Cavia porcellus 80.46 0.00e+00 1539.00
IUUC-Csa-023906 Chlorocebus sabaeus 99.21 0.00e+00 1948.00
IUUC-Dre-027568 Danio rerio 48.47 0.00e+00 841.00
IUUC-Dno-029098 Dasypus novemcinctus 81.12 0.00e+00 1495.00
IUUC-Dor-031102 Dipodomys ordii 74.84 0.00e+00 701.00
IUUC-Ete-032943 Echinops telfairi 76.70 0.00e+00 1113.00
IUUC-Eca-034310 Equus caballus 84.18 0.00e+00 1611.00
IUUC-Eeu-034589 Erinaceus europaeus 84.38 8.00e-165 574.00
IUUC-Fca-036252 Felis catus 79.62 0.00e+00 808.00
IUUC-Gac-041442 Gasterosteus aculeatus 46.10 0.00e+00 816.00
IUUC-Ggo-044861 Gorilla gorilla 96.46 0.00e+00 1824.00
IUUC-Hsa-046093 Homo sapiens 95.87 0.00e+00 1817.00
IUUC-Itr-048543 Ictidomys tridecemlineatus 81.77 0.00e+00 1477.00
IUUC-Lch-049454 Latimeria chalumnae 53.88 0.00e+00 926.00
IUUC-Laf-053553 Loxodonta africana 83.30 0.00e+00 1506.00
IUUC-Meu-056785 Macropus eugenii 53.40 4.00e-149 522.00
IUUC-Mvi-060491 Microbotryum violaceum 36.00 9.70e-01 28.90
IUUC-Mmr-060596 Microcebus murinus 84.27 0.00e+00 1600.00
IUUC-Mdo-062983 Monodelphis domestica 67.33 0.00e+00 1117.00
IUUC-Mmu-063951 Mus musculus 77.78 0.00e+00 1524.00
IUUC-Mpu-066412 Mustela putorius furo 82.53 0.00e+00 1614.00
IUUC-Mlu-067601 Myotis lucifugus 81.13 0.00e+00 1450.00
IUUC-Nle-069913 Nomascus leucogenys 95.37 0.00e+00 1515.00
IUUC-Opr-070999 Ochotona princeps 84.27 0.00e+00 990.00
IUUC-Ont-072512 Oreochromis niloticus 46.79 0.00e+00 889.00
IUUC-Oan-073564 Ornithorhynchus anatinus 62.30 0.00e+00 1105.00
IUUC-Ocu-074837 Oryctolagus cuniculus 86.54 0.00e+00 1646.00
IUUC-Ola-086555 Oryzias latipes 45.33 0.00e+00 811.00
IUUC-Oga-088909 Otolemur garnettii 84.18 0.00e+00 1611.00
IUUC-Oar-089315 Ovis aries 80.77 0.00e+00 1555.00
IUUC-Ptr-090542 Pan troglodytes 96.26 0.00e+00 1821.00
IUUC-Pan-092545 Papio anubis 99.21 0.00e+00 1911.00
IUUC-Pma-094167 Petromyzon marinus 33.18 6.00e-63 235.00
IUUC-Ppa-095344 Physcomitrella patens 36.92 1.00e-03 38.90
IUUC-Pfo-096976 Poecilia formosa 44.34 0.00e+00 822.00
IUUC-Pab-098481 Pongo abelii 95.96 0.00e+00 1810.00
IUUC-Pca-100135 Procavia capensis 77.06 0.00e+00 1300.00
IUUC-Pva-102127 Pteropus vampyrus 82.19 0.00e+00 1449.00
IUUC-Pte-104066 Pyrenophora teres 38.71 3.20e+00 28.50
IUUC-Rno-105783 Rattus norvegicus 79.80 0.00e+00 1506.00
IUUC-Sce-106163 Saccharomyces cerevisiae 25.96 3.70e-02 34.70
IUUC-Sar-113448 Sorex araneus 74.54 0.00e+00 923.00
IUUC-Tru-118708 Takifugu rubripes 44.54 0.00e+00 778.00
IUUC-Tni-120172 Tetraodon nigroviridis 36.84 2.00e-31 129.00
IUUC-Tbe-127661 Tupaia belangeri 87.15 0.00e+00 851.00
IUUC-Ttr-128318 Tursiops truncatus 78.05 0.00e+00 1428.00
IUUC-Vpa-130502 Vicugna pacos 73.95 5.00e-159 555.00
Created Date 25-Jun-2017

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