iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073596

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01284586

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000872.2	ENSOANT00000001353.2	ENSOANP00000001352.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.90e-15	57.2	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv++vv++e+f+ahk vL+a+S  Fy+ f+ +l+ +   +m++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIVVNREQFRAHKTVLMACSGLFYSIFTDQLKCN--LNMINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************86..79*****88*****************9875 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MALPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVNR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLN MINLDPEINP EGFCILLDFM YTSRLNLRES NIMAVMATAL YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGAATTGG GCTGTGTTGA TTCTTAGAAC TGGGGTTCTT AGAAGTGGTG ATGCAAGGAG 60
TTTCTAGGAA AGCCCGGAGA CCAGGTGATT ATTGCTGCTG CTGCTGCCGC TGCTACTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0042127--P:regulation of cell proliferation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	83.89	0.00e+00	1212.00
IUUC-Atr-002779	Amborella trichopoda	32.00	1.00e-06	47.80
IUUC-Apl-003263	Anas platyrhynchos	81.32	0.00e+00	1180.00
IUUC-Ame-010714	Astyanax mexicanus	60.58	0.00e+00	823.00
IUUC-Bta-012576	Bos taurus	84.55	0.00e+00	1209.00
IUUC-Cja-018906	Callithrix jacchus	85.11	0.00e+00	1233.00
IUUC-Cfa-021058	Canis familiaris	83.45	0.00e+00	1193.00
IUUC-Cpo-022328	Cavia porcellus	84.27	0.00e+00	1226.00
IUUC-Csa-023942	Chlorocebus sabaeus	84.45	0.00e+00	1222.00
IUUC-Cho-024599	Choloepus hoffmanni	83.86	0.00e+00	717.00
IUUC-Cin-025470	Ciona intestinalis	80.99	4.00e-60	225.00
IUUC-Csv-025860	Ciona savignyi	82.11	4.00e-60	225.00
IUUC-Dre-027605	Danio rerio	61.22	0.00e+00	838.00
IUUC-Dno-029476	Dasypus novemcinctus	78.75	0.00e+00	1155.00
IUUC-Dor-030724	Dipodomys ordii	83.99	0.00e+00	1203.00
IUUC-Ete-032678	Echinops telfairi	83.57	0.00e+00	1191.00
IUUC-Eca-034377	Equus caballus	85.39	0.00e+00	1234.00
IUUC-Eeu-034532	Erinaceus europaeus	79.91	0.00e+00	747.00
IUUC-Fca-036465	Felis catus	84.97	0.00e+00	1231.00
IUUC-Fal-036977	Ficedula albicollis	81.68	0.00e+00	1201.00
IUUC-Gmo-039515	Gadus morhua	81.09	7.00e-114	403.00
IUUC-Gga-040505	Gallus gallus	82.16	0.00e+00	1186.00
IUUC-Gac-041393	Gasterosteus aculeatus	60.08	0.00e+00	821.00
IUUC-Ggo-044500	Gorilla gorilla	84.45	0.00e+00	1225.00
IUUC-Hsa-046648	Homo sapiens	84.83	0.00e+00	1232.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	81.21	0.00e+00	1163.00
IUUC-Lch-050387	Latimeria chalumnae	59.25	0.00e+00	769.00
IUUC-Loc-052103	Lepisosteus oculatus	62.74	0.00e+00	880.00
IUUC-Laf-053636	Loxodonta africana	83.61	0.00e+00	1222.00
IUUC-Mcc-055290	Macaca mulatta	84.55	0.00e+00	1227.00
IUUC-Meu-055910	Macropus eugenii	79.66	0.00e+00	1163.00
IUUC-Mga-059925	Meleagris gallopavo	81.46	0.00e+00	1171.00
IUUC-Mvi-060431	Microbotryum violaceum	27.71	4.00e-03	35.40
IUUC-Mmr-060855	Microcebus murinus	85.25	0.00e+00	1227.00
IUUC-Mdo-062982	Monodelphis domestica	73.85	4.00e-82	297.00
IUUC-Mmu-063292	Mus musculus	84.01	0.00e+00	1195.00
IUUC-Mpu-066598	Mustela putorius furo	84.27	0.00e+00	1201.00
IUUC-Mlu-067370	Myotis lucifugus	83.73	0.00e+00	1204.00
IUUC-Nle-069870	Nomascus leucogenys	84.69	0.00e+00	1227.00
IUUC-Opr-070986	Ochotona princeps	82.58	0.00e+00	1165.00
IUUC-Ont-072475	Oreochromis niloticus	60.61	0.00e+00	776.00
IUUC-Ocu-073970	Oryctolagus cuniculus	84.03	0.00e+00	1228.00
IUUC-Ola-087102	Oryzias latipes	60.30	0.00e+00	822.00
IUUC-Oga-088873	Otolemur garnettii	84.59	0.00e+00	1228.00
IUUC-Oar-090083	Ovis aries	79.21	0.00e+00	1114.00
IUUC-Ptr-090628	Pan troglodytes	84.69	0.00e+00	1230.00
IUUC-Pan-092324	Papio anubis	84.45	0.00e+00	1219.00
IUUC-Psi-093695	Pelodiscus sinensis	81.60	0.00e+00	1144.00
IUUC-Pfo-096460	Poecilia formosa	59.86	0.00e+00	811.00
IUUC-Pab-098012	Pongo abelii	84.55	0.00e+00	1228.00
IUUC-Pca-100127	Procavia capensis	83.46	0.00e+00	1130.00
IUUC-Pva-102830	Pteropus vampyrus	83.57	0.00e+00	1203.00
IUUC-Rno-105752	Rattus norvegicus	84.43	0.00e+00	1197.00
IUUC-Sha-107259	Sarcophilus harrisii	83.50	0.00e+00	1204.00
IUUC-Sar-113610	Sorex araneus	80.94	0.00e+00	937.00
IUUC-Ssc-115327	Sus scrofa	84.55	0.00e+00	1225.00
IUUC-Tgu-116457	Taeniopygia guttata	82.44	0.00e+00	1210.00
IUUC-Tru-118520	Takifugu rubripes	59.64	0.00e+00	804.00
IUUC-Tsy-119245	Tarsius syrichta	70.09	1.00e-41	162.00
IUUC-Tni-119969	Tetraodon nigroviridis	59.86	0.00e+00	793.00
IUUC-Tbe-127327	Tupaia belangeri	78.23	0.00e+00	1107.00
IUUC-Ttr-129204	Tursiops truncatus	83.01	0.00e+00	1174.00
IUUC-Vpa-130647	Vicugna pacos	86.24	5.00e-56	211.00
IUUC-Xtr-132937	Xenopus tropicalis	67.98	0.00e+00	916.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence