iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-047996

Ensembl Protein ID

ENSSTOP00000006269.2

UniProt Accession

I3M8Y5; I3M8Y5_ICTTR

Genbank Protein ID

ENSSTOP00000006269

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01043459

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000006994.2	ENSSTOT00000007015.2	ENSSTOP00000006269.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.30e-43	146.6	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           ++ e+r+ l t+qd+vrk+Ld+t +l  y++++++e   ++i+a++++ g+m+aa l+L++L  +q+egWfr+fl
   Q: 1    MTSEQRRNLLTFQDYVRKILDPTHILC-YMAPWFREDKMQYIQAEKNNRGPMEAASLFLQFLleLQEEGWFRGFL 74
           5789***********************.*********************************************96 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTSEQRRNLL TFQDYVRKIL DPTHILCYMA PWFREDKMQY IQAEKNNRGP MEAASLFLQF 60
LLELQEEGWF RGFLDALNQA GYSGLYEAIE NWDFNKIEKL EVYRTLLKRL QPEFKNRIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGAGCG AGCAGCGCCG GAATCTGCTC ACCTTCCAAG ACTATGTCAG GAAGATTCTG 60
GATCCTACTC ACATTCTCTG CTACATGGCC CCCTGGTTTA GGGAGGGTGA GTGGTCTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	74.68	0.00e+00	1387.00
IUUC-Apl-003966	Anas platyrhynchos	52.50	0.00e+00	894.00
IUUC-Aca-004499	Anolis carolinensis	44.69	0.00e+00	748.00
IUUC-Ame-011950	Astyanax mexicanus	42.14	0.00e+00	661.00
IUUC-Bta-012489	Bos taurus	75.59	0.00e+00	1366.00
IUUC-Cel-018230	Caenorhabditis elegans	29.79	4.00e-67	249.00
IUUC-Cja-018716	Callithrix jacchus	78.11	0.00e+00	1433.00
IUUC-Cfa-020269	Canis familiaris	75.00	0.00e+00	1392.00
IUUC-Cpo-022507	Cavia porcellus	75.40	0.00e+00	1415.00
IUUC-Csa-024209	Chlorocebus sabaeus	79.20	0.00e+00	1473.00
IUUC-Cho-025104	Choloepus hoffmanni	68.87	0.00e+00	1091.00
IUUC-Cin-025792	Ciona intestinalis	32.74	3.00e-82	299.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.00	2.00e-21	98.60
IUUC-Dno-028954	Dasypus novemcinctus	74.03	0.00e+00	1353.00
IUUC-Eca-034039	Equus caballus	77.65	0.00e+00	1414.00
IUUC-Eeu-035009	Erinaceus europaeus	66.41	0.00e+00	876.00
IUUC-Fca-036169	Felis catus	76.62	0.00e+00	1436.00
IUUC-Fal-037579	Ficedula albicollis	53.67	0.00e+00	880.00
IUUC-Fso-038398	Fusarium solani	25.28	5.00e-20	93.60
IUUC-Ggo-045318	Gorilla gorilla	76.80	0.00e+00	1325.00
IUUC-Hsa-046671	Homo sapiens	79.52	0.00e+00	1449.00
IUUC-Lch-050461	Latimeria chalumnae	50.06	0.00e+00	826.00
IUUC-Loc-052582	Lepisosteus oculatus	46.96	0.00e+00	792.00
IUUC-Laf-054324	Loxodonta africana	73.90	0.00e+00	1344.00
IUUC-Mcc-055390	Macaca mulatta	78.76	0.00e+00	1462.00
IUUC-Meu-056365	Macropus eugenii	52.84	1.00e-169	590.00
IUUC-Mpo-057328	Magnaporthe poae	29.27	1.90e+00	28.50
IUUC-Mmr-061407	Microcebus murinus	78.87	0.00e+00	1499.00
IUUC-Mmu-063939	Mus musculus	74.21	0.00e+00	1344.00
IUUC-Mpu-066226	Mustela putorius furo	75.12	0.00e+00	1290.00
IUUC-Mlu-068092	Myotis lucifugus	75.30	0.00e+00	1358.00
IUUC-Nfi-068405	Neosartorya fischeri	25.44	3.00e-26	114.00
IUUC-Opr-070246	Ochotona princeps	64.14	0.00e+00	634.00
IUUC-Oan-072742	Ornithorhynchus anatinus	59.62	0.00e+00	945.00
IUUC-Ocu-073959	Oryctolagus cuniculus	73.02	0.00e+00	1350.00
IUUC-Oga-089173	Otolemur garnettii	76.92	0.00e+00	1422.00
IUUC-Oar-089369	Ovis aries	74.62	0.00e+00	1329.00
IUUC-Ptr-091032	Pan troglodytes	79.52	0.00e+00	1449.00
IUUC-Pan-092383	Papio anubis	79.11	0.00e+00	1463.00
IUUC-Psi-093432	Pelodiscus sinensis	54.64	0.00e+00	997.00
IUUC-Pma-094367	Petromyzon marinus	41.80	2.00e-112	399.00
IUUC-Pab-098416	Pongo abelii	78.81	0.00e+00	1347.00
IUUC-Pca-101006	Procavia capensis	72.41	8.00e-170	590.00
IUUC-Pva-102966	Pteropus vampyrus	76.91	0.00e+00	1424.00
IUUC-Pgr-103529	Puccinia graminis	27.61	2.00e-28	121.00
IUUC-Rno-105059	Rattus norvegicus	72.80	0.00e+00	858.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	26.53	6.00e-03	37.70
IUUC-Sar-113202	Sorex araneus	65.40	0.00e+00	969.00
IUUC-Ssc-116120	Sus scrofa	74.84	0.00e+00	1345.00
IUUC-Tgu-117314	Taeniopygia guttata	51.20	0.00e+00	889.00
IUUC-Tsy-119453	Tarsius syrichta	74.90	0.00e+00	779.00
IUUC-Tre-122194	Trichoderma reesei	25.28	1.00e-15	79.30
IUUC-Ttr-128421	Tursiops truncatus	72.27	0.00e+00	1119.00
IUUC-Vpa-130602	Vicugna pacos	74.12	0.00e+00	1311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence