iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044810

UUCD1 version

UUC-GoG-00327

Ensembl Protein ID

ENSGGOP00000007729.2

UniProt Accession

G3QY09; G3QY09_GORGO

Protein Name

Uncharacterized protein

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000007895.2	ENSGGOT00000007936.2	ENSGGOP00000007729.2
ENSGGOG00000007895.2	ENSGGOT00000034122.1	ENSGGOP00000022875.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.10	3.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKN SEPAPQPHRP LDPLTMHSTY DRAGAVPRTP LAGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCCAAAGTG AGTGAGCGGT GGCGGCGCCG GCCGGGGCAA 60
GTGGGCGAGA GGGCGGGGGC CGGGCCGCGG GTCGAGGTCT GCGCCTTCTG TCCGGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	90.57	0.00e+00	850.00
IUUC-Apl-003765	Anas platyrhynchos	79.41	0.00e+00	778.00
IUUC-Ame-010763	Astyanax mexicanus	60.34	8.00e-138	483.00
IUUC-Bta-012369	Bos taurus	92.40	0.00e+00	872.00
IUUC-Cja-019450	Callithrix jacchus	95.10	0.00e+00	894.00
IUUC-Cfa-020933	Canis familiaris	91.65	0.00e+00	864.00
IUUC-Cpo-022112	Cavia porcellus	89.87	0.00e+00	832.00
IUUC-Csa-023913	Chlorocebus sabaeus	84.24	0.00e+00	730.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.41	3.00e-33	136.00
IUUC-Cme-027209	Cyanidioschyzon merolae	36.17	3.00e-13	70.50
IUUC-Dre-027609	Danio rerio	59.31	1.00e-132	466.00
IUUC-Dno-029664	Dasypus novemcinctus	71.43	3.00e-143	502.00
IUUC-Ete-032988	Echinops telfairi	89.59	4.00e-164	570.00
IUUC-Eca-034430	Equus caballus	89.80	0.00e+00	836.00
IUUC-Fca-035968	Felis catus	93.84	9.00e-160	555.00
IUUC-Fal-037449	Ficedula albicollis	81.19	0.00e+00	764.00
IUUC-Fso-038103	Fusarium solani	34.74	3.00e-26	112.00
IUUC-Gmo-038925	Gadus morhua	59.31	1.00e-131	462.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.86	6.00e-29	122.00
IUUC-Gga-040362	Gallus gallus	83.37	0.00e+00	813.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.80	7.00e-125	440.00
IUUC-Hsa-045784	Homo sapiens	97.06	0.00e+00	911.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	88.91	0.00e+00	851.00
IUUC-Lch-049727	Latimeria chalumnae	69.31	4.00e-143	500.00
IUUC-Laf-054261	Loxodonta africana	90.49	0.00e+00	870.00
IUUC-Mcc-054931	Macaca mulatta	96.27	0.00e+00	897.00
IUUC-Meu-056468	Macropus eugenii	85.13	0.00e+00	832.00
IUUC-Mpo-057405	Magnaporthe poae	33.80	5.00e-28	119.00
IUUC-Mga-059981	Meleagris gallopavo	85.97	0.00e+00	676.00
IUUC-Mvi-060421	Microbotryum violaceum	28.84	2.00e-26	114.00
IUUC-Mmr-061181	Microcebus murinus	92.87	0.00e+00	870.00
IUUC-Mdo-062345	Monodelphis domestica	84.93	0.00e+00	833.00
IUUC-Mmu-063197	Mus musculus	84.47	0.00e+00	816.00
IUUC-Mpu-066275	Mustela putorius furo	90.27	0.00e+00	862.00
IUUC-Mlu-067194	Myotis lucifugus	91.46	0.00e+00	869.00
IUUC-Ncr-068929	Neurospora crassa	32.88	5.00e-26	112.00
IUUC-Ont-072227	Oreochromis niloticus	59.80	3.00e-130	458.00
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	94.40
IUUC-Ola-086865	Oryzias latipes	56.98	7.00e-129	454.00
IUUC-Oga-088945	Otolemur garnettii	93.54	0.00e+00	896.00
IUUC-Oar-089412	Ovis aries	90.04	0.00e+00	834.00
IUUC-Ptr-091550	Pan troglodytes	87.34	0.00e+00	652.00
IUUC-Pan-092183	Papio anubis	96.08	0.00e+00	910.00
IUUC-Psi-093003	Pelodiscus sinensis	81.80	0.00e+00	797.00
IUUC-Pfo-096704	Poecilia formosa	60.39	2.00e-133	469.00
IUUC-Pab-097923	Pongo abelii	96.59	0.00e+00	746.00
IUUC-Pca-100249	Procavia capensis	73.83	1.00e-132	466.00
IUUC-Pva-102562	Pteropus vampyrus	89.48	0.00e+00	827.00
IUUC-Rno-105762	Rattus norvegicus	85.05	0.00e+00	820.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	84.15	0.00e+00	825.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.25	1.00e-28	121.00
IUUC-Sar-113149	Sorex araneus	81.72	5.00e-118	417.00
IUUC-Ssc-115241	Sus scrofa	92.01	0.00e+00	876.00
IUUC-Tgu-116884	Taeniopygia guttata	82.14	0.00e+00	771.00
IUUC-Tru-118031	Takifugu rubripes	61.27	1.00e-137	483.00
IUUC-Tni-119766	Tetraodon nigroviridis	61.27	1.00e-132	466.00
IUUC-Ttr-128556	Tursiops truncatus	83.92	0.00e+00	728.00
IUUC-Xtr-131866	Xenopus tropicalis	75.48	0.00e+00	733.00
IUUC-Xma-133963	Xiphophorus maculatus	60.39	3.00e-127	448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence