iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000008451.2	ENSCJAT00000016526.2	ENSCJAP00000015640.2
ENSCJAG00000008451.2	ENSCJAT00000016523.2	ENSCJAP00000015637.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.20e-12	46.5	425	476

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ +deL++   dv++ i  e  degW++g    +g  GlfP+n+v+ l
   Q: 425  VALYDYQGEGSDELSFDPDDVITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 476
           58**********************9..9*********..8*************977 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK 60
VSEEHDVLKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYIAEVEKH SSQTDAAKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTTCTCAC TCCAAAGTGG CAGCAGCCAG AGAGGGAGTC GGTGTGGACG TGAGGAGCCG 60
GGCGCTTAGA ACAGAGGCTC GCACAGGTGG AGGTAGGTAC TCTGAGCCAT GGGACGGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	83.33	0.00e+00	714.00
IUUC-Apl-003745	Anas platyrhynchos	56.42	1.00e-81	296.00
IUUC-Aca-004438	Anolis carolinensis	63.23	6.00e-78	285.00
IUUC-Ame-011504	Astyanax mexicanus	69.59	2.00e-76	280.00
IUUC-Bta-012591	Bos taurus	83.64	0.00e+00	661.00
IUUC-Cel-018639	Caenorhabditis elegans	57.14	2.00e-17	84.00
IUUC-Cfa-020262	Canis familiaris	81.50	0.00e+00	644.00
IUUC-Cpo-021362	Cavia porcellus	83.68	0.00e+00	651.00
IUUC-Csa-023911	Chlorocebus sabaeus	90.52	0.00e+00	718.00
IUUC-Cin-025677	Ciona intestinalis	54.09	7.00e-64	238.00
IUUC-Csv-026140	Ciona savignyi	57.89	2.00e-61	230.00
IUUC-Dre-028127	Danio rerio	69.59	2.00e-91	330.00
IUUC-Dno-029332	Dasypus novemcinctus	62.86	5.00e-87	315.00
IUUC-Dor-030437	Dipodomys ordii	74.01	2.00e-168	585.00
IUUC-Dme-031931	Drosophila melanogaster	47.17	2.00e-68	253.00
IUUC-Ete-033160	Echinops telfairi	74.12	3.00e-150	525.00
IUUC-Eca-033269	Equus caballus	81.82	0.00e+00	698.00
IUUC-Eeu-035032	Erinaceus europaeus	71.99	3.00e-120	424.00
IUUC-Fca-035999	Felis catus	78.93	0.00e+00	723.00
IUUC-Fal-037107	Ficedula albicollis	49.35	1.00e-120	426.00
IUUC-Gmo-038507	Gadus morhua	64.91	1.00e-18	88.20
IUUC-Gga-040335	Gallus gallus	66.55	2.00e-104	372.00
IUUC-Gac-042253	Gasterosteus aculeatus	67.28	2.00e-85	310.00
IUUC-Ggo-044505	Gorilla gorilla	85.04	0.00e+00	697.00
IUUC-Hsa-046728	Homo sapiens	92.46	1.00e-172	599.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	67.70	5.00e-168	583.00
IUUC-Lch-050221	Latimeria chalumnae	76.82	5.00e-98	351.00
IUUC-Loc-052855	Lepisosteus oculatus	65.74	4.00e-83	301.00
IUUC-Laf-054202	Loxodonta africana	80.65	0.00e+00	665.00
IUUC-Mcc-055824	Macaca mulatta	92.07	0.00e+00	728.00
IUUC-Mga-059791	Meleagris gallopavo	55.64	4.00e-81	295.00
IUUC-Mmr-061281	Microcebus murinus	75.31	3.00e-169	587.00
IUUC-Mdo-062515	Monodelphis domestica	68.02	9.00e-151	526.00
IUUC-Mmu-064341	Mus musculus	80.49	0.00e+00	675.00
IUUC-Mpu-066565	Mustela putorius furo	84.97	0.00e+00	676.00
IUUC-Mlu-066942	Myotis lucifugus	79.25	0.00e+00	661.00
IUUC-Nle-069436	Nomascus leucogenys	91.02	0.00e+00	723.00
IUUC-Opr-070288	Ochotona princeps	76.56	7.00e-164	570.00
IUUC-Ont-071712	Oreochromis niloticus	72.35	2.00e-89	323.00
IUUC-Oan-073528	Ornithorhynchus anatinus	40.76	3.00e-42	165.00
IUUC-Ocu-074686	Oryctolagus cuniculus	81.10	9.00e-178	616.00
IUUC-Ola-086894	Oryzias latipes	58.48	1.00e-93	337.00
IUUC-Oga-088585	Otolemur garnettii	77.30	0.00e+00	658.00
IUUC-Oar-089686	Ovis aries	83.88	0.00e+00	693.00
IUUC-Ptr-090461	Pan troglodytes	93.30	3.00e-174	604.00
IUUC-Pan-091887	Papio anubis	91.46	0.00e+00	719.00
IUUC-Psi-093785	Pelodiscus sinensis	51.55	3.00e-138	485.00
IUUC-Pma-094161	Petromyzon marinus	65.58	7.00e-56	211.00
IUUC-Pfo-097391	Poecilia formosa	67.28	3.00e-87	315.00
IUUC-Pab-098222	Pongo abelii	90.62	0.00e+00	713.00
IUUC-Pca-100668	Procavia capensis	80.50	0.00e+00	659.00
IUUC-Pva-102767	Pteropus vampyrus	71.96	2.00e-162	565.00
IUUC-Rno-106001	Rattus norvegicus	82.78	0.00e+00	676.00
IUUC-Sha-106912	Sarcophilus harrisii	92.63	4.00e-116	411.00
IUUC-Sar-113338	Sorex araneus	74.13	9.00e-168	583.00
IUUC-Ssc-116027	Sus scrofa	82.42	0.00e+00	711.00
IUUC-Tgu-117472	Taeniopygia guttata	57.75	2.00e-150	525.00
IUUC-Tru-118637	Takifugu rubripes	60.66	1.00e-80	293.00
IUUC-Tni-119931	Tetraodon nigroviridis	56.79	1.00e-91	330.00
IUUC-Xtr-131797	Xenopus tropicalis	66.82	3.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence