iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000006755.6	ENSGALT00000040829.3	ENSGALP00000040033.3
ENSGALG00000006755.6	ENSGALT00000063235.1	ENSGALP00000055844.1
ENSGALG00000006755.6	ENSGALT00000084322.1	ENSGALP00000063447.1
ENSGALG00000006755.6	ENSGALT00000040826.3	ENSGALP00000040030.3
ENSGALG00000006755.6	ENSGALT00000056762.1	ENSGALP00000048135.1
ENSGALG00000006755.6	ENSGALT00000079359.1	ENSGALP00000054973.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-87	294.3	56	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           tGl+NlgNtC+mNS+LQcLsn++elr+++l+ ++ ++ln++  + + ++l+++++kl++ lw +s + +vsp+e++++++++a++f gy
   Q: 56   TGLRNLGNTCFMNSILQCLSNTKELRDYCLQnQYLRDLNNN--SRMRTALMSEFAKLIQLLWtSSPNDSVSPSEFKTQIQRYAPRFVGY 142
           7******************************6666777655..78*****************999999********************* PP
   S: 88   eqqDaqEflaflldqleeelkk.....eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           +qqDaqEfl+flld+l+ e+++     ++n ++ +   +d  e+s++ +++ +++++s +sdlF gqlks+++c ec+  s+ ++pf+d
   Q: 143  NQQDAQEFLRFLLDGLHGEVNRvlvrpRANADTLDHLPDD--EKSRQMWRRYQEREDSRVSDLFVGQLKSSLTCSECGYCSTAFDPFWD 229
           ********************99666444444444443333..5666689**************************************** PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
           lslp+p+k    + +l dcL+ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ + +k+++ v+fpl+ L
   Q: 230  LSLPIPKKGYG-EVTLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRF--SEARIRASKLTTFVNFPLKdL 315
           *******9976.779***************************************************..9999***************** PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYva 297
           dl++f +++++    +  Y+L+av +HsG++ +GHY+ 
   Q: 316  DLREFASQSCN----HAVYNLYAVSNHSGTTMGGHYTP 349
           ********775....679******************96 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRDSYTVTLP EEPPALPDLH KELRPRTSMP GSLLVSTFVG LVLNKTKSSK VVQGLTGLRN 60
LGNTCFMNSI LQCLSNTKEL RDYCLQNQYL RDLNNNSRMR TALMSEFAKL IQLLWTSSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCCTGGGG TGGGCACTGT CTGGTGTCGG TCGTAGCCCA TGCAGCTGAG CCCAGCCCCT 60
TCTCTTGCAG CCGATGCCTC CAGCCGAGCC CGCTGAGCCT CAGCCTCCAG CATGTCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	84.16	4.00e-147	514.00
IUUC-Aca-005132	Anolis carolinensis	87.06	6.00e-164	570.00
IUUC-Ame-011102	Astyanax mexicanus	75.31	5.00e-143	500.00
IUUC-Bta-012529	Bos taurus	81.45	1.00e-147	516.00
IUUC-Cja-019016	Callithrix jacchus	77.60	4.00e-131	461.00
IUUC-Cfa-020714	Canis familiaris	83.83	1.00e-146	513.00
IUUC-Cpo-021727	Cavia porcellus	82.51	4.00e-144	504.00
IUUC-Csa-023071	Chlorocebus sabaeus	83.61	2.00e-147	514.00
IUUC-Cin-025797	Ciona intestinalis	53.18	3.00e-90	324.00
IUUC-Csv-026132	Ciona savignyi	54.49	1.00e-92	333.00
IUUC-Dre-027872	Danio rerio	77.07	2.00e-163	568.00
IUUC-Dno-029329	Dasypus novemcinctus	84.16	2.00e-156	545.00
IUUC-Dor-030574	Dipodomys ordii	84.16	7.00e-144	503.00
IUUC-Dme-032208	Drosophila melanogaster	49.01	1.00e-74	274.00
IUUC-Ete-032725	Echinops telfairi	82.35	8.00e-65	241.00
IUUC-Eca-033361	Equus caballus	84.16	8.00e-147	513.00
IUUC-Eeu-035272	Erinaceus europaeus	84.15	5.00e-84	305.00
IUUC-Fca-036497	Felis catus	84.16	3.00e-147	514.00
IUUC-Fal-036766	Ficedula albicollis	97.02	4.00e-167	580.00
IUUC-Gmo-039129	Gadus morhua	63.26	3.00e-125	441.00
IUUC-Gac-042475	Gasterosteus aculeatus	65.93	3.00e-133	468.00
IUUC-Ggo-044814	Gorilla gorilla	73.41	2.00e-127	448.00
IUUC-Hsa-045937	Homo sapiens	83.39	6.00e-145	507.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	84.05	4.00e-146	511.00
IUUC-Lch-050527	Latimeria chalumnae	80.13	5.00e-150	524.00
IUUC-Loc-052697	Lepisosteus oculatus	76.28	2.00e-142	498.00
IUUC-Laf-054167	Loxodonta africana	83.01	1.00e-152	533.00
IUUC-Mcc-055584	Macaca mulatta	83.72	5.00e-146	511.00
IUUC-Meu-056542	Macropus eugenii	84.72	2.00e-146	512.00
IUUC-Mga-060020	Meleagris gallopavo	99.33	7.00e-170	590.00
IUUC-Mmr-060989	Microcebus murinus	83.83	8.00e-146	510.00
IUUC-Mdo-062761	Monodelphis domestica	84.72	2.00e-146	512.00
IUUC-Mmu-063710	Mus musculus	82.84	2.00e-145	509.00
IUUC-Mpu-066573	Mustela putorius furo	84.16	4.00e-147	514.00
IUUC-Mlu-067359	Myotis lucifugus	46.15	3.00e-76	279.00
IUUC-Nle-070013	Nomascus leucogenys	79.01	1.00e-145	509.00
IUUC-Opr-070907	Ochotona princeps	80.44	3.00e-144	504.00
IUUC-Ont-071573	Oreochromis niloticus	68.82	1.00e-136	479.00
IUUC-Oan-073105	Ornithorhynchus anatinus	76.57	2.00e-126	445.00
IUUC-Ocu-073941	Oryctolagus cuniculus	80.76	4.00e-146	511.00
IUUC-Ola-086724	Oryzias latipes	66.57	7.00e-140	489.00
IUUC-Oga-088973	Otolemur garnettii	83.83	1.00e-145	509.00
IUUC-Oar-089916	Ovis aries	81.13	2.00e-157	548.00
IUUC-Ptr-090998	Pan troglodytes	83.39	4.00e-145	508.00
IUUC-Pan-092686	Papio anubis	83.72	6.00e-146	510.00
IUUC-Psi-093284	Pelodiscus sinensis	76.49	6.00e-119	419.00
IUUC-Pma-094462	Petromyzon marinus	67.72	1.00e-77	281.00
IUUC-Pfo-097352	Poecilia formosa	79.22	5.00e-150	524.00
IUUC-Pab-098688	Pongo abelii	81.95	2.00e-129	455.00
IUUC-Pca-100205	Procavia capensis	80.40	3.00e-142	498.00
IUUC-Pva-103188	Pteropus vampyrus	83.22	1.00e-144	506.00
IUUC-Rno-105853	Rattus norvegicus	82.84	7.00e-145	507.00
IUUC-Sha-107237	Sarcophilus harrisii	84.72	2.00e-146	512.00
IUUC-Sar-113103	Sorex araneus	76.51	3.00e-134	470.00
IUUC-Ssc-115955	Sus scrofa	83.50	8.00e-146	510.00
IUUC-Tgu-116894	Taeniopygia guttata	97.01	2.00e-167	581.00
IUUC-Tru-117703	Takifugu rubripes	62.92	6.00e-120	423.00
IUUC-Tsy-118879	Tarsius syrichta	84.49	2.00e-146	511.00
IUUC-Tni-119866	Tetraodon nigroviridis	74.79	2.00e-157	547.00
IUUC-Tbe-127367	Tupaia belangeri	82.43	2.00e-70	259.00
IUUC-Ttr-128773	Tursiops truncatus	80.59	3.00e-139	488.00
IUUC-Vpa-130402	Vicugna pacos	84.68	8.00e-105	374.00
IUUC-Xtr-132658	Xenopus tropicalis	77.71	2.00e-137	482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence