iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066579

Ensembl Protein ID

ENSMPUP00000005512.1

UniProt Accession

M3Y2G1; M3Y2G1_MUSPF

Genbank Protein ID

ENSMPUP00000005512

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01081428

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005554.1	ENSMPUT00000005605.1	ENSMPUP00000005512.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.60e-79	265.0	66	507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  ++ a s+ +l+++++++++e  +
   Q: 66   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSFEDKDKPDakvrIIPLQLQRLFAQLLVLDQDAASTADLTDSFGWTSNE--E 152
           9*****************************888877665543322234458899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +q++c+ec+nvs+++e+fldl+++
   Q: 153  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTVVNQVVCKECKNVSEKQEDFLDLTVA 215
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L  +f++ee ++++n y+c +c+++++a+k+ kl+klP++L++ L Rf+f+  +  r k +++++fpl+++l+p
   Q: 216  VKNVS-----GLEDALwTMFVEEEVFDCDNLYHCGTCDRLVKATKSAKLRKLPPFLTVSLLRFNFDFVKRERYKETSCYTFPLRINLKP 299
           *****.....9*****99*********************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++++++  ++ Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 300  FCEQSDSDDL-EYVYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeeeskpvlsfkdlqneeeidddpliilkaillqeennvipv 387
           ****888876.9***************************************************************************** PP
   S: 302  ................................................................................ekgk....W 306
                                                                                           +       W
   Q: 388  dqlgqkllkktgmswnkkyrrqygplrkflklhsqifllssdestvsllkngflqaesdfqrndqhifktftsespglndK--TscphW 474
           ************************************************************999999999999988887531..24688* PP
   S: 307  llfdDskVtevkeeevleetg..staYvlfYkr 337
           + ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 475  FDINDSKVQPIKEKDIERQFQgkESAYMLFYRK 507
           ******************9889*********98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVVSNVGLSR LLGLGFRQVG SSFTMFGDLF EEDYSSVSNY QYGKEKKLKT KTLEPPAPRE 60
FTNLSGIRNQ GGTCYLNSLL QTLHFTPEFR EALFSLGPEE LGSFEDKDKP DAKVRIIPLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCCTTAAA TGGCCCACGC TCCAGGCCGC GGGAGACTTC CCCGCACCAG CATGGCTGCG 60
CCCATTTGGG GCGCGTATGG TTGTTTCGAA TGTGGGTCTG AGCCGGCTCC TGGGGCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	89.73	0.00e+00	2060.00
IUUC-Apl-004105	Anas platyrhynchos	62.42	0.00e+00	1515.00
IUUC-Aca-004715	Anolis carolinensis	60.65	0.00e+00	1438.00
IUUC-Ame-011073	Astyanax mexicanus	46.77	0.00e+00	1020.00
IUUC-Bta-012487	Bos taurus	81.41	0.00e+00	1937.00
IUUC-Cja-018937	Callithrix jacchus	80.86	0.00e+00	1959.00
IUUC-Cfa-020645	Canis familiaris	84.58	0.00e+00	1324.00
IUUC-Cpo-022160	Cavia porcellus	77.22	0.00e+00	1866.00
IUUC-Csa-023078	Chlorocebus sabaeus	80.11	0.00e+00	1974.00
IUUC-Cho-025013	Choloepus hoffmanni	61.95	0.00e+00	766.00
IUUC-Csv-026193	Ciona savignyi	54.55	1.00e-58	219.00
IUUC-Dre-027416	Danio rerio	48.27	0.00e+00	1125.00
IUUC-Dno-029639	Dasypus novemcinctus	76.22	0.00e+00	1583.00
IUUC-Dor-030624	Dipodomys ordii	86.75	2.00e-146	513.00
IUUC-Ete-032626	Echinops telfairi	61.19	0.00e+00	725.00
IUUC-Eca-034208	Equus caballus	83.27	0.00e+00	2018.00
IUUC-Eeu-035340	Erinaceus europaeus	46.59	2.00e-93	337.00
IUUC-Fca-035886	Felis catus	81.62	0.00e+00	852.00
IUUC-Fal-036925	Ficedula albicollis	61.62	0.00e+00	1402.00
IUUC-Gmo-038597	Gadus morhua	45.69	0.00e+00	905.00
IUUC-Gga-041171	Gallus gallus	61.48	0.00e+00	1484.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.65	0.00e+00	958.00
IUUC-Ggo-045069	Gorilla gorilla	79.18	0.00e+00	1798.00
IUUC-Hsa-046715	Homo sapiens	80.58	0.00e+00	1972.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	77.08	0.00e+00	1844.00
IUUC-Lch-050182	Latimeria chalumnae	51.11	0.00e+00	1123.00
IUUC-Loc-052705	Lepisosteus oculatus	54.03	0.00e+00	1237.00
IUUC-Laf-054132	Loxodonta africana	79.40	0.00e+00	1936.00
IUUC-Mcc-055734	Macaca mulatta	79.79	0.00e+00	1985.00
IUUC-Meu-056135	Macropus eugenii	83.26	2.00e-111	397.00
IUUC-Mga-060092	Meleagris gallopavo	61.84	0.00e+00	1468.00
IUUC-Mmr-061546	Microcebus murinus	77.82	0.00e+00	1892.00
IUUC-Mdo-061935	Monodelphis domestica	60.79	0.00e+00	1476.00
IUUC-Mmu-063630	Mus musculus	76.15	0.00e+00	1870.00
IUUC-Mlu-068034	Myotis lucifugus	81.58	0.00e+00	1930.00
IUUC-Nle-069082	Nomascus leucogenys	78.22	0.00e+00	1623.00
IUUC-Opr-070953	Ochotona princeps	68.74	0.00e+00	944.00
IUUC-Ont-072435	Oreochromis niloticus	46.27	0.00e+00	1072.00
IUUC-Oan-073339	Ornithorhynchus anatinus	64.82	0.00e+00	1523.00
IUUC-Ocu-073760	Oryctolagus cuniculus	78.82	0.00e+00	1923.00
IUUC-Ola-087015	Oryzias latipes	47.30	0.00e+00	939.00
IUUC-Oga-088960	Otolemur garnettii	80.82	0.00e+00	1974.00
IUUC-Oar-089853	Ovis aries	82.08	0.00e+00	1976.00
IUUC-Ptr-091093	Pan troglodytes	80.58	0.00e+00	1971.00
IUUC-Pan-091962	Papio anubis	79.32	0.00e+00	1957.00
IUUC-Psi-093691	Pelodiscus sinensis	64.79	0.00e+00	1564.00
IUUC-Pma-094428	Petromyzon marinus	64.03	2.00e-89	322.00
IUUC-Pfo-096983	Poecilia formosa	47.97	0.00e+00	1023.00
IUUC-Pab-097860	Pongo abelii	79.79	0.00e+00	1833.00
IUUC-Pca-100514	Procavia capensis	77.80	0.00e+00	630.00
IUUC-Pva-102771	Pteropus vampyrus	80.36	0.00e+00	1828.00
IUUC-Rno-105405	Rattus norvegicus	75.34	0.00e+00	1823.00
IUUC-Sha-107376	Sarcophilus harrisii	63.04	0.00e+00	1456.00
IUUC-Ssc-115819	Sus scrofa	76.77	0.00e+00	1349.00
IUUC-Tgu-117262	Taeniopygia guttata	60.75	0.00e+00	1484.00
IUUC-Tru-117601	Takifugu rubripes	46.56	0.00e+00	1071.00
IUUC-Tsy-118996	Tarsius syrichta	71.42	0.00e+00	1559.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.80	0.00e+00	860.00
IUUC-Tbe-127616	Tupaia belangeri	60.49	0.00e+00	1186.00
IUUC-Ttr-129075	Tursiops truncatus	78.44	0.00e+00	1814.00
IUUC-Vpa-130108	Vicugna pacos	80.84	0.00e+00	1752.00
IUUC-Xtr-132623	Xenopus tropicalis	51.57	0.00e+00	1177.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence