iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009817.1	ENSONIT00000012345.1	ENSONIP00000012336.1
ENSONIG00000009817.1	ENSONIT00000012346.1	ENSONIP00000012337.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-21	75.6	149	183
UBD/Beta-Prp	3.90e-40	138.3	511	802

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrt 32
           gH ++vt+ +f   ++++lv+ s D t +vWDl+t
   Q: 149  GHLGPVTSAEFcpwNNDILVTTSEDRTFRVWDLKT 183
           8*******99999777****************987 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..ghedsv 97
           + ++c+++s d+++++ g  d+t+ +++     + + + gh+++++++++s ++ + +++seD  +++w   ++++ +++     ++ +
   Q: 511  KHVSCLQYSGDGKQILCGLGDSTLLLYKSCLTGAPAVYIGHDKPISSLSWSLSRRWWLSASEDLSLQIWTHCNSEPAIIMGdkMFSKPI 599
           56788***********************9999999999***************99**************66666655555422678889 PP
   S: 98   lslsfspsgdklvsGsh.drtirvwdle.tgqclee.............tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgk 170
           +  +f+  +++++ +s    ++ +++l+ t+  ++              t +  ++++   +++++   ++  ++ Dr ++++d++ g+
   Q: 600  RGAQFYYLDKFVLLASGpSLYLYLYNLDiTRDDIKRyhqrsvstlagcfTTTSATDIIALSAINDFFsHIVLVCGSDRSIQVFDMNKGT 688
           999999966666666651446777766533333333667888889999988888888888888888879******************** PP
   S: 171  llrtltgghtdsvysls......fdsng....kelvsgsldgtvklwdlqtgecvrtlnghtd..nvksvrfspnderlvsgssDgsir 247
           +  +   +h +++++++      f+s+     + +++ +     k+wdl+t +cvr++++h +  +++s + sp + ++++gs+D+  +
   Q: 689  VASEVPDAHSRAIHCITqnkgsaFSSQApdsyNLFLTSAVTDGMKIWDLRTLRCVRRYENHVNrcQPCSSAISPCGRFIATGSEDNCAY 777
           *****999*********666666555448999888888888899*****************9633789********************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvav 272
           ++d+rs+++l+ lq+h ++v  va+
   Q: 778  VYDIRSSNYLHRLQKHSDTVLNVAF 802
           ***********************98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAKMLTEKLS LTCDRLLSHR QLACCYSYFS IPRHGKEVLV YSTKDGKQKP LVLTGHHGDI 60
SALTFGKRSS PVILCSASAD YVIVWDIELC QKRTQEGKVA AGTIIGTLLG EVVHLSFCFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAAATCTG TTCGGTGTCA TAGCAACGAT CAACATTTCT AAAGCGATTA AAGCGTCGAC 60
GAGCACGGAC AGTTAATAAT AACGACAGTA ACTGTATGAG TATGCACACA CAGTTAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	37.93	1.00e-115	410.00
IUUC-Aca-004807	Anolis carolinensis	42.77	6.00e-178	617.00
IUUC-Bta-013316	Bos taurus	39.71	2.00e-146	513.00
IUUC-Cja-018825	Callithrix jacchus	41.27	4.00e-172	598.00
IUUC-Cfa-020895	Canis familiaris	42.33	1.00e-165	577.00
IUUC-Cpo-022282	Cavia porcellus	36.61	3.00e-148	519.00
IUUC-Csa-023439	Chlorocebus sabaeus	41.49	8.00e-159	554.00
IUUC-Cho-025046	Choloepus hoffmanni	35.22	4.00e-85	309.00
IUUC-Dre-028376	Danio rerio	51.34	0.00e+00	714.00
IUUC-Dno-029649	Dasypus novemcinctus	39.05	4.00e-123	435.00
IUUC-Dor-030824	Dipodomys ordii	36.19	9.00e-106	378.00
IUUC-Eca-033270	Equus caballus	41.54	1.00e-169	590.00
IUUC-Fca-036149	Felis catus	39.95	6.00e-159	555.00
IUUC-Fal-037410	Ficedula albicollis	42.22	2.00e-143	503.00
IUUC-Gmo-038923	Gadus morhua	57.68	0.00e+00	684.00
IUUC-Gga-040974	Gallus gallus	40.61	6.00e-165	574.00
IUUC-Gac-042310	Gasterosteus aculeatus	69.07	0.00e+00	812.00
IUUC-Ggo-044557	Gorilla gorilla	41.75	2.00e-173	603.00
IUUC-Hsa-046312	Homo sapiens	42.37	4.00e-178	618.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	39.35	2.00e-150	526.00
IUUC-Laf-054450	Loxodonta africana	41.98	6.00e-162	564.00
IUUC-Mcc-055807	Macaca mulatta	37.83	1.00e-123	437.00
IUUC-Meu-056116	Macropus eugenii	32.94	3.00e-30	127.00
IUUC-Mga-060088	Meleagris gallopavo	39.81	4.00e-138	485.00
IUUC-Mdo-062857	Monodelphis domestica	42.62	1.00e-174	606.00
IUUC-Mmu-063220	Mus musculus	37.50	6.00e-124	438.00
IUUC-Mpu-066921	Mustela putorius furo	39.93	2.00e-155	543.00
IUUC-Mlu-067717	Myotis lucifugus	38.37	2.00e-109	389.00
IUUC-Nle-069061	Nomascus leucogenys	35.08	3.00e-126	446.00
IUUC-Opr-070612	Ochotona princeps	40.76	8.00e-51	195.00
IUUC-Oan-072701	Ornithorhynchus anatinus	38.28	1.00e-77	283.00
IUUC-Ocu-074602	Oryctolagus cuniculus	39.07	3.00e-162	565.00
IUUC-Ola-086633	Oryzias latipes	57.12	0.00e+00	732.00
IUUC-Oga-088499	Otolemur garnettii	41.54	2.00e-167	582.00
IUUC-Oar-089256	Ovis aries	38.53	1.00e-147	517.00
IUUC-Ptr-091545	Pan troglodytes	37.14	1.00e-91	330.00
IUUC-Pan-092299	Papio anubis	40.71	8.00e-168	584.00
IUUC-Psi-093010	Pelodiscus sinensis	41.36	5.00e-176	611.00
IUUC-Pab-097646	Pongo abelii	35.90	5.00e-85	309.00
IUUC-Pca-100720	Procavia capensis	34.98	5.00e-61	229.00
IUUC-Pva-102808	Pteropus vampyrus	42.90	3.00e-79	290.00
IUUC-Rno-105715	Rattus norvegicus	39.15	6.00e-151	528.00
IUUC-Sha-107546	Sarcophilus harrisii	42.43	1.00e-178	620.00
IUUC-Sar-113543	Sorex araneus	33.56	7.00e-102	365.00
IUUC-Ssc-116335	Sus scrofa	45.67	1.00e-24	107.00
IUUC-Tgu-117249	Taeniopygia guttata	38.93	4.00e-141	495.00
IUUC-Tsy-119238	Tarsius syrichta	35.80	1.00e-140	493.00
IUUC-Tni-120639	Tetraodon nigroviridis	56.63	1.00e-117	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence