iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094749

UUCD1 version

UUC-PeM-00254

Ensembl Protein ID

ENSPMAP00000008823.1

UniProt Accession

S4RUD3; S4RUD3_PETMA

Protein Name

Uncharacterized protein

Gene Name

FBXW7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000008000.1	ENSPMAT00000008862.1	ENSPMAP00000008823.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-63	206.4	476	510
UBD/Beta-Prp	8.40e-101	336.3	228	507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           H++ vtcl+f + +l+v++sdDgt+k+WDlrtg+ l
   Q: 476  HQSAVTCLQF-SrKLVVTSSDDGTVKLWDLRTGDFL 510
           9*********.339*******************977 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           +lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++  +  i+v+gs+Drt+kvw+ +tg+cvhtl g
   Q: 228  VLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRGN--IIVSGSTDRTLKVWNADTGQCVHTLYG 312
           789************..****************************************999..*************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++v++++++   +++vsGs+d t+rvwd+etgqcl+ +l+gh ++v+cv++++  + +vsG++D tv++Wd +++++l+tl+g ht+
   Q: 313  HTSTVRCMHLHG--NRVVSGSRDATLRVWDIETGQCLH-VLAGHVAAVRCVQYDG--RRVVSGAYDYTVKVWDPESETCLHTLQG-HTN 395
           ***********9..************************.****************..***************************9.*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
           +vysl+fd    ++vsgsld+++++wd +tg+c++tl gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq++n++ ++v
   Q: 396  RVYSLQFDG--VHIVSGSLDTSIRVWDAETGTCLHTLVGHQSLTSGMELR--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAV 480
           ********9..9**************************************..************************************* PP
   S: 271  avlsfgdnvlvlgsedskvniwklkkn 297
           ++l+f+++ +v+ s+d++v++w+l++ 
   Q: 481  TCLQFSRKLVVTSSDDGTVKLWDLRTG 507
           ************************976 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

TAKMGFYGTL KMIFHKMKRK SEHGPDMRAL SPGKKPCKGS EHPSHALGSL LPCTSVPTTF 60
GELRAASGQG QGSSRRRLAG VTPPAELQDW LRTFQSWSGP ERLLALDELI DRCEPPQIKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGCCAAGA TGGGCTTCTA CGGCACACTC AAGATGATCT TTCATAAAGT AAGTTTCAAA 60
AAAAGATGTG CTTAATGTCA TCCCCCTTGT TTAAGTTGAG CACCAGTCAG ATGCCAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	83.30	0.00e+00	951.00
IUUC-Apl-003489	Anas platyrhynchos	82.70	0.00e+00	954.00
IUUC-Aca-005318	Anolis carolinensis	83.21	0.00e+00	976.00
IUUC-Ago-007794	Ashbya gossypii	29.75	4.00e-59	221.00
IUUC-Acl-008123	Aspergillus clavatus	32.14	3.00e-73	268.00
IUUC-Afl-008730	Aspergillus flavus	33.20	1.00e-73	270.00
IUUC-Afu-009014	Aspergillus fumigatus	33.07	2.00e-73	269.00
IUUC-Ani-009332	Aspergillus nidulans	33.90	4.00e-78	283.00
IUUC-Ang-009529	Aspergillus niger	34.02	1.00e-74	273.00
IUUC-Aor-010215	Aspergillus oryzae	32.62	7.00e-73	266.00
IUUC-Ate-010535	Aspergillus terreus	39.72	9.00e-68	249.00
IUUC-Ame-010898	Astyanax mexicanus	82.75	0.00e+00	932.00
IUUC-Bgr-012075	Blumeria graminis	34.66	4.00e-80	291.00
IUUC-Bta-012391	Bos taurus	83.66	0.00e+00	974.00
IUUC-Bci-013725	Botrytis cinerea	34.38	8.00e-79	286.00
IUUC-Cel-018495	Caenorhabditis elegans	49.30	2.00e-130	457.00
IUUC-Cja-018902	Callithrix jacchus	83.49	0.00e+00	952.00
IUUC-Cfa-020237	Canis familiaris	83.49	0.00e+00	952.00
IUUC-Cpo-022234	Cavia porcellus	83.39	0.00e+00	977.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	37.27	3.00e-53	201.00
IUUC-Csa-023532	Chlorocebus sabaeus	83.49	0.00e+00	952.00
IUUC-Cho-025026	Choloepus hoffmanni	69.74	0.00e+00	625.00
IUUC-Cin-025516	Ciona intestinalis	69.75	4.00e-138	482.00
IUUC-Csv-026312	Ciona savignyi	74.52	0.00e+00	746.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	35.83	4.00e-85	307.00
IUUC-Cne-027018	Cryptococcus neoformans	31.30	1.00e-72	266.00
IUUC-Cme-027168	Cyanidioschyzon merolae	29.93	4.00e-33	134.00
IUUC-Dre-028303	Danio rerio	80.95	0.00e+00	933.00
IUUC-Dno-029576	Dasypus novemcinctus	81.47	0.00e+00	933.00
IUUC-Dor-030196	Dipodomys ordii	82.39	0.00e+00	932.00
IUUC-Dse-031558	Dothistroma septosporum	40.96	1.00e-71	263.00
IUUC-Dme-031702	Drosophila melanogaster	78.71	0.00e+00	804.00
IUUC-Ete-032791	Echinops telfairi	78.31	0.00e+00	888.00
IUUC-Eca-033424	Equus caballus	83.39	0.00e+00	976.00
IUUC-Eeu-034996	Erinaceus europaeus	81.10	0.00e+00	930.00
IUUC-Fca-036422	Felis catus	83.49	0.00e+00	953.00
IUUC-Fal-037267	Ficedula albicollis	82.76	0.00e+00	949.00
IUUC-Fox-037800	Fusarium oxysporum	35.27	3.00e-85	308.00
IUUC-Fso-038258	Fusarium solani	35.83	2.00e-84	305.00
IUUC-Gmo-039119	Gadus morhua	73.04	0.00e+00	827.00
IUUC-Ggr-039781	Gaeumannomyces graminis	36.25	2.00e-85	308.00
IUUC-Gga-040667	Gallus gallus	83.67	0.00e+00	955.00
IUUC-Gac-042423	Gasterosteus aculeatus	75.09	0.00e+00	810.00
IUUC-Gma-042658	Glycine max	33.22	7.00e-38	149.00
IUUC-Ggo-044422	Gorilla gorilla	83.49	0.00e+00	952.00
IUUC-Hsa-045898	Homo sapiens	83.49	0.00e+00	952.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	88.44	0.00e+00	880.00
IUUC-Kpa-049097	Komagataella pastoris	32.73	1.00e-77	283.00
IUUC-Lch-050414	Latimeria chalumnae	83.67	0.00e+00	957.00
IUUC-Loc-052348	Lepisosteus oculatus	84.38	0.00e+00	980.00
IUUC-Lma-053185	Leptosphaeria maculans	34.64	4.00e-75	275.00
IUUC-Laf-054054	Loxodonta africana	83.67	0.00e+00	954.00
IUUC-Mcc-055056	Macaca mulatta	83.49	0.00e+00	952.00
IUUC-Meu-056778	Macropus eugenii	78.46	7.00e-147	513.00
IUUC-Mor-057076	Magnaporthe oryzae	36.11	1.00e-85	308.00
IUUC-Mpo-057423	Magnaporthe poae	41.04	1.00e-71	263.00
IUUC-Mtr-058429	Medicago truncatula	34.00	4.00e-32	130.00
IUUC-Mla-059081	Melampsora laricipopulina	33.40	6.00e-78	283.00
IUUC-Mga-059255	Meleagris gallopavo	83.67	0.00e+00	955.00
IUUC-Mvi-060490	Microbotryum violaceum	40.40	9.00e-67	247.00
IUUC-Mmr-061292	Microcebus murinus	83.49	0.00e+00	952.00
IUUC-Mdo-062304	Monodelphis domestica	83.30	0.00e+00	956.00
IUUC-Mmu-063610	Mus musculus	83.12	0.00e+00	950.00
IUUC-Mpu-065931	Mustela putorius furo	83.49	0.00e+00	952.00
IUUC-Mlu-066976	Myotis lucifugus	83.49	0.00e+00	955.00
IUUC-Nfi-068428	Neosartorya fischeri	33.27	6.00e-74	270.00
IUUC-Ncr-068688	Neurospora crassa	37.21	2.00e-88	318.00
IUUC-Nle-070174	Nomascus leucogenys	83.49	0.00e+00	952.00
IUUC-Opr-070851	Ochotona princeps	69.79	1.00e-154	538.00
IUUC-Ont-071997	Oreochromis niloticus	82.59	0.00e+00	983.00
IUUC-Oan-072936	Ornithorhynchus anatinus	83.30	0.00e+00	952.00
IUUC-Ocu-074742	Oryctolagus cuniculus	83.49	0.00e+00	954.00
IUUC-Ola-087098	Oryzias latipes	81.42	0.00e+00	948.00
IUUC-Olu-087837	Ostreococcus lucimarinus	33.71	3.00e-37	146.00
IUUC-Oga-088884	Otolemur garnettii	87.60	0.00e+00	704.00
IUUC-Oar-090220	Ovis aries	82.88	0.00e+00	947.00
IUUC-Ptr-090492	Pan troglodytes	83.49	0.00e+00	952.00
IUUC-Pan-091770	Papio anubis	83.49	0.00e+00	952.00
IUUC-Psi-093207	Pelodiscus sinensis	83.39	0.00e+00	977.00
IUUC-Pno-095026	Phaeosphaeria nodorum	37.25	3.00e-69	255.00
IUUC-Pfo-096493	Poecilia formosa	83.12	0.00e+00	947.00
IUUC-Pab-098141	Pongo abelii	83.39	0.00e+00	976.00
IUUC-Pop-099988	Populus trichocarpa	33.44	3.00e-39	154.00
IUUC-Pca-100571	Procavia capensis	81.87	0.00e+00	660.00
IUUC-Ppe-101291	Prunus persica	35.00	8.00e-43	166.00
IUUC-Pva-102988	Pteropus vampyrus	83.49	0.00e+00	952.00
IUUC-Pgr-103597	Puccinia graminis	42.64	6.00e-60	224.00
IUUC-Ptt-103853	Puccinia triticina	30.94	6.00e-51	193.00
IUUC-Pte-104275	Pyrenophora teres	34.34	3.00e-77	281.00
IUUC-Pyt-104438	Pyrenophora triticirepentis	34.03	6.00e-77	280.00
IUUC-Rno-105706	Rattus norvegicus	83.30	0.00e+00	951.00
IUUC-Sce-106314	Saccharomyces cerevisiae	30.47	5.00e-61	227.00
IUUC-Sha-107653	Sarcophilus harrisii	83.30	0.00e+00	953.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	34.14	2.00e-79	288.00
IUUC-Spo-108115	Schizosaccharomyces pombe	31.66	2.00e-61	229.00
IUUC-Sly-111880	Solanum lycopersicum	33.89	7.00e-36	142.00
IUUC-Stu-112051	Solanum tuberosum	33.22	2.00e-35	141.00
IUUC-Sar-113600	Sorex araneus	78.17	0.00e+00	869.00
IUUC-Sre-114901	Sporisorium reilianum	45.99	3.00e-65	242.00
IUUC-Ssc-115787	Sus scrofa	81.65	0.00e+00	922.00
IUUC-Tgu-117510	Taeniopygia guttata	83.67	0.00e+00	954.00
IUUC-Tru-117819	Takifugu rubripes	82.57	0.00e+00	961.00
IUUC-Tsy-118828	Tarsius syrichta	83.49	0.00e+00	952.00
IUUC-Tni-120468	Tetraodon nigroviridis	81.93	0.00e+00	976.00
IUUC-Tre-122193	Trichoderma reesei	37.74	7.00e-88	316.00
IUUC-Tvi-122615	Trichoderma virens	36.25	3.00e-86	311.00
IUUC-Tme-127021	Tuber melanosporum	36.65	6.00e-86	310.00
IUUC-Tbe-127925	Tupaia belangeri	83.46	0.00e+00	950.00
IUUC-Ttr-128899	Tursiops truncatus	83.49	0.00e+00	952.00
IUUC-Uma-129449	Ustilago maydis	45.62	7.00e-65	241.00
IUUC-Vda-129802	Verticillium dahliae	37.63	4.00e-89	320.00
IUUC-Vpa-130082	Vicugna pacos	83.11	0.00e+00	792.00
IUUC-Vvi-131551	Vitis vinifera	34.23	2.00e-39	154.00
IUUC-Xtr-132213	Xenopus tropicalis	83.30	0.00e+00	953.00
IUUC-Xma-133646	Xiphophorus maculatus	83.15	0.00e+00	968.00
IUUC-Yli-134429	Yarrowia lipolytica	34.81	6.00e-84	303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence