iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044489

UUCD1 version

UUC-GoG-00045

Ensembl Protein ID

ENSGGOP00000001012.2

UniProt Accession

G3QFE2; G3QFE2_GORGO

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001028.2	ENSGGOT00000024872.1	ENSGGOP00000020679.1
ENSGGOG00000001028.2	ENSGGOT00000001035.2	ENSGGOP00000001012.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-42	141.4	237	277
UBD/Beta-Prp	3.20e-54	184.6	191	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 237  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 277
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 191  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 278
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 279  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 367
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 368  HENRVSTLRVSPDGTAFCSGSWDHTLRLW 396
           ***************************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSTCA EIMATEGLHE NETLASLKSE 60
AESNKGKKKQ NQKKKNHTRI QVHQVAERVE ALGQFVMKTR RTLKGHGNKV LCMDWCKDKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT CGTTAATGTA TTTGGCTCAT GTGACAAATG TTTCAAACAA 60
CGAGCTCTGA GACCAGTTTT CAAGAAGTCT CAACAACTCA GCTACTGTTC AACATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.91	0.00e+00	747.00
IUUC-Apl-003399	Anas platyrhynchos	99.04	0.00e+00	650.00
IUUC-Aca-004861	Anolis carolinensis	89.65	0.00e+00	738.00
IUUC-Ame-011851	Astyanax mexicanus	87.54	0.00e+00	647.00
IUUC-Bta-012438	Bos taurus	94.63	0.00e+00	687.00
IUUC-Cel-018408	Caenorhabditis elegans	63.87	7.00e-131	459.00
IUUC-Cja-019086	Callithrix jacchus	95.95	0.00e+00	777.00
IUUC-Cfa-021255	Canis familiaris	93.67	0.00e+00	736.00
IUUC-Cpo-021398	Cavia porcellus	92.95	0.00e+00	756.00
IUUC-Csa-023776	Chlorocebus sabaeus	95.20	0.00e+00	690.00
IUUC-Cin-025305	Ciona intestinalis	56.13	2.00e-123	435.00
IUUC-Csv-026058	Ciona savignyi	56.80	9.00e-123	432.00
IUUC-Dre-028432	Danio rerio	81.06	0.00e+00	661.00
IUUC-Dno-029958	Dasypus novemcinctus	86.30	2.00e-145	507.00
IUUC-Dor-031013	Dipodomys ordii	98.82	3.00e-152	531.00
IUUC-Dme-031889	Drosophila melanogaster	64.93	1.00e-138	485.00
IUUC-Eca-033977	Equus caballus	91.67	0.00e+00	746.00
IUUC-Eeu-035079	Erinaceus europaeus	94.15	0.00e+00	756.00
IUUC-Fca-035693	Felis catus	91.41	0.00e+00	749.00
IUUC-Fal-037345	Ficedula albicollis	94.35	0.00e+00	686.00
IUUC-Gmo-039222	Gadus morhua	92.74	0.00e+00	636.00
IUUC-Gga-040320	Gallus gallus	94.35	0.00e+00	687.00
IUUC-Gac-042644	Gasterosteus aculeatus	87.01	0.00e+00	648.00
IUUC-Hsa-046434	Homo sapiens	95.96	0.00e+00	780.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.99	7.00e-177	612.00
IUUC-Loc-052790	Lepisosteus oculatus	86.80	0.00e+00	700.00
IUUC-Laf-054255	Loxodonta africana	93.92	0.00e+00	761.00
IUUC-Mcc-055610	Macaca mulatta	95.44	0.00e+00	773.00
IUUC-Meu-056819	Macropus eugenii	86.04	0.00e+00	687.00
IUUC-Mga-059740	Meleagris gallopavo	86.50	0.00e+00	709.00
IUUC-Mmr-061221	Microcebus murinus	95.20	0.00e+00	775.00
IUUC-Mdo-062619	Monodelphis domestica	93.79	0.00e+00	686.00
IUUC-Mmu-064266	Mus musculus	95.20	0.00e+00	776.00
IUUC-Mpu-065766	Mustela putorius furo	99.00	0.00e+00	626.00
IUUC-Mlu-067221	Myotis lucifugus	89.70	0.00e+00	734.00
IUUC-Nle-069515	Nomascus leucogenys	99.05	0.00e+00	660.00
IUUC-Opr-070195	Ochotona princeps	86.80	0.00e+00	684.00
IUUC-Ont-071535	Oreochromis niloticus	75.25	7.00e-168	583.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.30	6.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.33	0.00e+00	627.00
IUUC-Ola-086578	Oryzias latipes	88.14	0.00e+00	638.00
IUUC-Oga-089090	Otolemur garnettii	94.47	0.00e+00	768.00
IUUC-Oar-090017	Ovis aries	91.14	0.00e+00	732.00
IUUC-Ptr-091280	Pan troglodytes	89.65	0.00e+00	725.00
IUUC-Pan-092198	Papio anubis	99.05	0.00e+00	660.00
IUUC-Psi-093030	Pelodiscus sinensis	84.83	0.00e+00	707.00
IUUC-Pma-094140	Petromyzon marinus	76.28	9.00e-94	335.00
IUUC-Pfo-097182	Poecilia formosa	88.14	0.00e+00	642.00
IUUC-Pab-098157	Pongo abelii	95.48	0.00e+00	693.00
IUUC-Pca-100988	Procavia capensis	73.74	1.00e-158	552.00
IUUC-Pva-102232	Pteropus vampyrus	82.07	2.00e-165	575.00
IUUC-Rno-105526	Rattus norvegicus	91.32	0.00e+00	653.00
IUUC-Sha-106754	Sarcophilus harrisii	93.18	0.00e+00	742.00
IUUC-Ssc-115390	Sus scrofa	94.96	0.00e+00	771.00
IUUC-Tgu-117377	Taeniopygia guttata	87.02	0.00e+00	695.00
IUUC-Tru-117938	Takifugu rubripes	88.14	0.00e+00	638.00
IUUC-Tsy-119392	Tarsius syrichta	81.57	0.00e+00	634.00
IUUC-Tni-119834	Tetraodon nigroviridis	69.70	4.00e-161	560.00
IUUC-Tbe-127469	Tupaia belangeri	91.78	0.00e+00	689.00
IUUC-Ttr-128252	Tursiops truncatus	91.44	0.00e+00	731.00
IUUC-Vpa-130173	Vicugna pacos	80.47	3.00e-156	544.00
IUUC-Xtr-131803	Xenopus tropicalis	88.13	0.00e+00	713.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence