iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049513

Ensembl Protein ID

ENSLACP00000001932.1

UniProt Accession

H2ZX11; H2ZX11_LATCH

Genbank Protein ID

ENSLACP00000001932

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01022435

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000001725.1	ENSLACT00000001946.1	ENSLACP00000001932.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.70e-82	275.1	444	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNSvLQ+L++ +++r+++       l+e    +++++l+++lq+lf+ l +s++ a+sp ++l+a +   + fs  +qq
   Q: 444  GLVNLGNTCYMNSVLQALFMASDFRQAVMY-----LKE----SDSQPLMMKLQRLFAFLEHSQRPAISPDNFLAASW--PPWFSPGAQQ 521
           9*****************************.....554....4678***************************9987..788******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee k     ++ +++  ++++ +    e+ +  +k+li+++F+g+l +++ cl c+n+s ree f+dlsl++p  
   Q: 522  DCSEYLKYLLDRLHEEEKT---GRRINLKLRRSNSGPY--IEEYQDFGKTLIEKMFGGKLMTNTCCLCCHNISLREEAFTDLSLAFPPP 605
           *****************44...3333333333333333..36789999***************************************** PP
   S: 180  eetkke................................................................................... 185
           ++ + +                                                                                   
   Q: 606  QKAAVRyggstspalpieeigpksthsplksqnrmcrspkrqrsplkseqpyvhivpieilgshgkveterptfsrqyteeledhdgie 694
           *99888*********************************************************************************** PP
   S: 186  ....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
                               s+ d+++ f ++e+l+g+nkyyce c ++q+aek +++++ P +Lil L Rfsf+ + ++r+ki ++v+
   Q: 695  daknsaiasgeqthaadgsrSVPDLINFFLSPEMLTGDNKYYCEMCASLQDAEKVVEVSEAPCYLILTLLRFSFDLKVMKRRKIIDNVY 783
           ***************************************************************************************** PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn..........ekgkWllfdDskVtevkeeevleetg....s 328
           +pl L+l  + +s          Y+L++vvvHsG s++sGHY++y+++          +  +W+lf+D++V+ ++ e+v + t+    +
   Q: 784  VPLVLKLP-VRVS---------VYDLCSVVVHSGiSSESGHYYCYAREglgtnesqadSGSQWYLFNDTRVSFSSFESVSNVTSylpkD 862
           *****997.4444.........7*************************99997776654555*******************999***** PP
   S: 329  taYvlfYkrr 338
           taYvlfY++r
   Q: 863  TAYVLFYRQR 872
           *******985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MDKILEAVLV SPYSNAVKHG LIRRVLEAAK EPLDRQQCWS MLEVATKLFL LGDTKLKRDT 60
GKEVFEAYAH HHPKEFEEFF SVRFILNLLQ EGYGTLGTKS LKIIEYLHLG LQYLLQGSSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAAA TACTAGAAGC TGTTTTGGTG TCTCCTTACT CCAACGCAGT CAAACATGGT 60
CTCATAAGGC GTGTGCTTGA AGCAGCAAAG GAGCCCTTAG ACAGGCAACA ATGCTGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004121	Anas platyrhynchos	63.02	0.00e+00	1145.00
IUUC-Aca-005070	Anolis carolinensis	57.33	0.00e+00	731.00
IUUC-Bta-012545	Bos taurus	62.60	0.00e+00	763.00
IUUC-Cpo-021961	Cavia porcellus	57.82	0.00e+00	887.00
IUUC-Dno-029186	Dasypus novemcinctus	57.85	8.00e-154	537.00
IUUC-Dor-030538	Dipodomys ordii	61.61	0.00e+00	654.00
IUUC-Eeu-035120	Erinaceus europaeus	49.92	1.00e-168	587.00
IUUC-Fal-037625	Ficedula albicollis	62.45	0.00e+00	1157.00
IUUC-Gga-040767	Gallus gallus	63.39	0.00e+00	1207.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	58.69	0.00e+00	998.00
IUUC-Loc-052698	Lepisosteus oculatus	55.56	0.00e+00	1028.00
IUUC-Laf-053999	Loxodonta africana	57.44	0.00e+00	985.00
IUUC-Meu-056906	Macropus eugenii	65.27	0.00e+00	872.00
IUUC-Mga-059595	Meleagris gallopavo	61.74	0.00e+00	1150.00
IUUC-Mdo-062167	Monodelphis domestica	62.06	0.00e+00	1132.00
IUUC-Mmu-063298	Mus musculus	56.01	0.00e+00	1011.00
IUUC-Mpu-066195	Mustela putorius furo	58.87	0.00e+00	763.00
IUUC-Mlu-067583	Myotis lucifugus	56.19	0.00e+00	733.00
IUUC-Opr-070454	Ochotona princeps	50.43	3.00e-85	310.00
IUUC-Ocu-074121	Oryctolagus cuniculus	52.46	0.00e+00	827.00
IUUC-Oga-088593	Otolemur garnettii	57.50	0.00e+00	975.00
IUUC-Oar-090140	Ovis aries	62.44	0.00e+00	754.00
IUUC-Pan-092168	Papio anubis	62.24	0.00e+00	761.00
IUUC-Psi-093707	Pelodiscus sinensis	63.60	0.00e+00	1187.00
IUUC-Pca-100683	Procavia capensis	55.14	0.00e+00	724.00
IUUC-Rno-105061	Rattus norvegicus	61.50	0.00e+00	762.00
IUUC-Sha-106686	Sarcophilus harrisii	64.44	0.00e+00	849.00
IUUC-Tgu-117024	Taeniopygia guttata	64.07	0.00e+00	1180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence