iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066001

Ensembl Protein ID

ENSMPUP00000007991.1

UniProt Accession

M3Y9I4; M3Y9I4_MUSPF

Genbank Protein ID

ENSMPUP00000007991

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01075039

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008049.1	ENSMPUT00000008116.1	ENSMPUP00000007991.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-37	124.1	233	263
UBD/Beta-Prp	3.90e-58	197.0	56	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 233  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 263
           99*********999****************8 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 56   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 144
           455666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   ++
   Q: 145  HNKVINSVDIKQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALggGKA 232
           ************999*****************9999998.99******************************************99556 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdn 224
           h++ +y +s+++++++l+s+s d+t k+wd++ +++v+t++  ++ 
   Q: 233  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVNTFTMGSTV 278
           ***************************************9876544 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPYEIKKVFA SLPQVERGVS KIIGGDPKGN NFLYTNGKCV ILRNIDNPAL ADIYTEHAHQ 60
VVVAKYAPSG FYIASGDVSG KLRIWDTTQK EHLLKYEYQP FAGKIKDIAW TEDSKRIAVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGAGGGG CGGCCCGGTC CGCGCAGCCT CACGCGGGCT GCAGTCGCCG AGCTGAGCGC 60
TTGACTATAT ATGGTCAAAG CTGGGGGCGA GCCGCGCGCG GGACCGCGCT TCCGGGTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.10	3.00e-79	288.00
IUUC-Aml-002368	Ailuropoda melanoleuca	94.39	0.00e+00	1182.00
IUUC-Atr-003160	Amborella trichopoda	35.95	1.00e-111	397.00
IUUC-Apl-004012	Anas platyrhynchos	85.06	0.00e+00	1073.00
IUUC-Aca-004707	Anolis carolinensis	80.13	0.00e+00	1044.00
IUUC-Aly-006465	Arabidopsis lyrata	36.52	2.00e-108	386.00
IUUC-Ath-006740	Arabidopsis thaliana	36.21	2.00e-107	382.00
IUUC-Ago-007920	Ashbya gossypii	26.85	2.00e-69	256.00
IUUC-Acl-008262	Aspergillus clavatus	35.85	7.00e-103	367.00
IUUC-Afl-008471	Aspergillus flavus	33.01	2.00e-77	283.00
IUUC-Afu-008989	Aspergillus fumigatus	35.81	3.00e-95	342.00
IUUC-Ani-009167	Aspergillus nidulans	36.65	3.00e-113	402.00
IUUC-Ang-009595	Aspergillus niger	36.08	2.00e-101	362.00
IUUC-Aor-009908	Aspergillus oryzae	35.91	3.00e-101	362.00
IUUC-Ate-010580	Aspergillus terreus	36.62	2.00e-106	380.00
IUUC-Ame-011269	Astyanax mexicanus	60.50	9.00e-134	470.00
IUUC-Bgr-011996	Blumeria graminis	34.01	2.00e-104	373.00
IUUC-Bta-013278	Bos taurus	92.05	0.00e+00	1195.00
IUUC-Bci-013925	Botrytis cinerea	34.80	2.00e-105	376.00
IUUC-Bdi-014659	Brachypodium distachyon	34.49	3.00e-101	362.00
IUUC-Bol-016043	Brassica oleracea	34.65	3.00e-104	372.00
IUUC-Bra-017139	Brassica rapa	35.64	5.00e-106	378.00
IUUC-Cel-018417	Caenorhabditis elegans	39.23	6.00e-120	424.00
IUUC-Cja-019952	Callithrix jacchus	92.69	0.00e+00	1156.00
IUUC-Cfa-020225	Canis familiaris	94.12	0.00e+00	1191.00
IUUC-Cpo-021900	Cavia porcellus	90.87	0.00e+00	1156.00
IUUC-Csa-023028	Chlorocebus sabaeus	93.64	0.00e+00	1163.00
IUUC-Cho-025030	Choloepus hoffmanni	66.29	0.00e+00	749.00
IUUC-Cin-025152	Ciona intestinalis	56.03	1.00e-81	295.00
IUUC-Csv-025986	Ciona savignyi	35.66	2.00e-88	319.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	37.05	1.00e-109	390.00
IUUC-Cne-026814	Cryptococcus neoformans	33.38	3.00e-95	342.00
IUUC-Dre-027498	Danio rerio	80.51	9.00e-96	342.00
IUUC-Dno-029383	Dasypus novemcinctus	91.57	0.00e+00	1139.00
IUUC-Dor-030633	Dipodomys ordii	90.24	0.00e+00	1071.00
IUUC-Dse-031526	Dothistroma septosporum	37.17	3.00e-114	405.00
IUUC-Dme-031597	Drosophila melanogaster	46.18	2.00e-165	575.00
IUUC-Ete-032780	Echinops telfairi	78.46	0.00e+00	988.00
IUUC-Eca-034306	Equus caballus	91.99	0.00e+00	1142.00
IUUC-Eeu-034531	Erinaceus europaeus	74.45	1.00e-135	476.00
IUUC-Fca-036301	Felis catus	93.43	0.00e+00	1197.00
IUUC-Fal-037361	Ficedula albicollis	85.19	0.00e+00	1120.00
IUUC-Fox-037924	Fusarium oxysporum	34.69	5.00e-99	355.00
IUUC-Fso-038199	Fusarium solani	34.01	2.00e-95	343.00
IUUC-Gmo-039238	Gadus morhua	69.52	0.00e+00	884.00
IUUC-Ggr-039830	Gaeumannomyces graminis	40.48	2.00e-84	306.00
IUUC-Gga-040235	Gallus gallus	85.85	0.00e+00	1099.00
IUUC-Gac-042363	Gasterosteus aculeatus	69.05	0.00e+00	912.00
IUUC-Gma-044189	Glycine max	36.33	2.00e-110	393.00
IUUC-Ggo-044632	Gorilla gorilla	91.90	0.00e+00	1135.00
IUUC-Hsa-045792	Homo sapiens	94.28	0.00e+00	1190.00
IUUC-Hvu-047517	Hordeum vulgare	33.91	2.00e-104	373.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	93.43	0.00e+00	1171.00
IUUC-Kpa-049183	Komagataella pastoris	32.65	9.00e-85	307.00
IUUC-Lch-050428	Latimeria chalumnae	73.97	0.00e+00	991.00
IUUC-Lpe-051306	Leersia perrieri	34.80	9.00e-106	377.00
IUUC-Loc-052096	Lepisosteus oculatus	69.80	0.00e+00	890.00
IUUC-Lma-053313	Leptosphaeria maculans	37.70	4.00e-114	407.00
IUUC-Laf-054060	Loxodonta africana	89.51	0.00e+00	1130.00
IUUC-Mcc-055619	Macaca mulatta	91.64	0.00e+00	1134.00
IUUC-Meu-056689	Macropus eugenii	78.39	0.00e+00	635.00
IUUC-Mor-056940	Magnaporthe oryzae	40.44	3.00e-83	302.00
IUUC-Mpo-057557	Magnaporthe poae	29.28	4.00e-67	248.00
IUUC-Mtr-057922	Medicago truncatula	35.28	3.00e-107	382.00
IUUC-Mla-059103	Melampsora laricipopulina	32.49	1.00e-73	271.00
IUUC-Mga-060150	Meleagris gallopavo	85.49	0.00e+00	1087.00
IUUC-Mvi-060448	Microbotryum violaceum	30.29	1.00e-71	264.00
IUUC-Mmr-061226	Microcebus murinus	91.41	0.00e+00	1148.00
IUUC-Mdo-062674	Monodelphis domestica	89.03	0.00e+00	1140.00
IUUC-Mmu-064170	Mus musculus	91.57	0.00e+00	1168.00
IUUC-Mac-065124	Musa acuminata	36.59	7.00e-110	391.00
IUUC-Mlu-067253	Myotis lucifugus	91.51	0.00e+00	1165.00
IUUC-Nfi-068550	Neosartorya fischeri	35.78	4.00e-109	388.00
IUUC-Ncr-068948	Neurospora crassa	35.76	7.00e-113	400.00
IUUC-Nle-070115	Nomascus leucogenys	89.80	0.00e+00	1066.00
IUUC-Opr-070254	Ochotona princeps	89.57	0.00e+00	1093.00
IUUC-Ont-071666	Oreochromis niloticus	72.97	0.00e+00	949.00
IUUC-Oan-073594	Ornithorhynchus anatinus	86.52	3.00e-165	574.00
IUUC-Ocu-074824	Oryctolagus cuniculus	90.94	0.00e+00	1128.00
IUUC-Oba-075010	Oryza barthii	35.23	6.00e-107	381.00
IUUC-Obr-076364	Oryza brachyantha	36.21	6.00e-108	384.00
IUUC-Ogl-077019	Oryza glaberrima	35.23	6.00e-107	381.00
IUUC-Ogu-078496	Oryza glumaepatula	35.23	6.00e-107	381.00
IUUC-Oin-080116	Oryza indica	35.39	2.00e-107	382.00
IUUC-Olo-080290	Oryza longistaminata	35.23	1.00e-106	380.00
IUUC-Ome-081969	Oryza meridionalis	35.23	8.00e-107	380.00
IUUC-Oni-082075	Oryza nivara	35.23	6.00e-107	381.00
IUUC-Opu-083959	Oryza punctata	35.28	1.00e-106	380.00
IUUC-Oru-084711	Oryza rufipogon	35.23	6.00e-107	381.00
IUUC-Osa-085958	Oryza sativa	35.39	2.00e-107	382.00
IUUC-Ola-086968	Oryzias latipes	74.24	0.00e+00	965.00
IUUC-Oga-089108	Otolemur garnettii	92.59	0.00e+00	1204.00
IUUC-Oar-089986	Ovis aries	86.57	0.00e+00	1102.00
IUUC-Ptr-091281	Pan troglodytes	94.38	0.00e+00	1180.00
IUUC-Pan-092585	Papio anubis	93.80	0.00e+00	1165.00
IUUC-Psi-093811	Pelodiscus sinensis	83.36	0.00e+00	1103.00
IUUC-Pma-094542	Petromyzon marinus	67.46	0.00e+00	878.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.12	1.00e-106	380.00
IUUC-Ppa-095876	Physcomitrella patens	34.86	6.00e-108	384.00
IUUC-Pfo-096973	Poecilia formosa	72.66	0.00e+00	978.00
IUUC-Pab-098391	Pongo abelii	93.48	0.00e+00	1167.00
IUUC-Pop-098850	Populus trichocarpa	35.49	6.00e-108	384.00
IUUC-Pca-100257	Procavia capensis	50.29	8.00e-76	278.00
IUUC-Ppe-101578	Prunus persica	36.69	6.00e-112	398.00
IUUC-Pva-102872	Pteropus vampyrus	88.41	0.00e+00	1133.00
IUUC-Pgr-103593	Puccinia graminis	31.78	9.00e-75	274.00
IUUC-Pte-104365	Pyrenophora teres	38.22	3.00e-109	389.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	37.60	2.00e-111	396.00
IUUC-Rno-105737	Rattus norvegicus	92.05	0.00e+00	1199.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.36	2.00e-65	243.00
IUUC-Sha-107084	Sarcophilus harrisii	86.30	0.00e+00	1004.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	34.81	2.00e-108	386.00
IUUC-Spo-108309	Schizosaccharomyces pombe	32.28	9.00e-93	334.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	34.48	4.00e-105	375.00
IUUC-Smo-109255	Selaginella moellendorffii	33.54	8.00e-97	347.00
IUUC-Sit-109962	Setaria italica	36.28	2.00e-109	389.00
IUUC-Sly-110897	Solanum lycopersicum	37.22	1.00e-112	400.00
IUUC-Stu-111971	Solanum tuberosum	37.22	4.00e-112	398.00
IUUC-Sar-113415	Sorex araneus	72.69	1.00e-109	390.00
IUUC-Sbi-114857	Sorghum bicolor	35.75	4.00e-107	381.00
IUUC-Sre-114900	Sporisorium reilianum	32.13	1.00e-87	317.00
IUUC-Tgu-117256	Taeniopygia guttata	84.96	0.00e+00	1113.00
IUUC-Tru-117871	Takifugu rubripes	67.68	0.00e+00	874.00
IUUC-Tsy-119172	Tarsius syrichta	97.08	6.00e-139	487.00
IUUC-Tni-120339	Tetraodon nigroviridis	67.73	0.00e+00	911.00
IUUC-Tca-121609	Theobroma cacao	35.87	5.00e-110	391.00
IUUC-Tre-122076	Trichoderma reesei	34.76	4.00e-92	332.00
IUUC-Tvi-122528	Trichoderma virens	33.44	1.00e-94	340.00
IUUC-Tae-123530	Triticum aestivum	34.28	9.00e-106	377.00
IUUC-Tur-126845	Triticum urartu	34.05	1.00e-77	283.00
IUUC-Tme-127217	Tuber melanosporum	34.89	6.00e-103	368.00
IUUC-Tbe-127526	Tupaia belangeri	90.30	0.00e+00	1149.00
IUUC-Ttr-128898	Tursiops truncatus	85.08	0.00e+00	1085.00
IUUC-Uma-129631	Ustilago maydis	30.82	3.00e-90	326.00
IUUC-Vda-129732	Verticillium dahliae	34.20	4.00e-91	328.00
IUUC-Vvi-131217	Vitis vinifera	37.46	3.00e-110	392.00
IUUC-Xtr-132860	Xenopus tropicalis	72.34	0.00e+00	943.00
IUUC-Xma-133830	Xiphophorus maculatus	72.97	0.00e+00	982.00
IUUC-Yli-134335	Yarrowia lipolytica	31.97	2.00e-73	269.00
IUUC-Zma-135907	Zea mays	35.75	7.00e-108	384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence