iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062482

UUCD1 version

UUC-MoD-00348

Ensembl Protein ID

ENSMODP00000003858.3

UniProt Accession

F6WDF5; F6WDF5_MONDO

Protein Name

Uncharacterized protein

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000003165.3	ENSMODT00000003944.3	ENSMODP00000003858.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-56	185.5	1699	1729
UBD/Beta-Prp	2.40e-127	424.4	726	941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    d.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1699 DgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1729
           52699999898889***************75 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd  i +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++ +g
   Q: 726  HDDDILCLAIHPLKDYVATGqvGRDPAIHIWDTETIKPLSILkGYHQYGVCAVDFSADGKRLASVGIDdsHTIVLWDWKKGEKLSITRG 814
           4555666************95569******************55599*****************999999******************* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           ++d++  ++++p+  dkl++++  +  + w    g  +         g+ ++ +c+v+  ++ + +sG+  + v +W  k  +l++t +
   Q: 815  NKDKIFVVKMNPYMpDKLITAG-IKHMKFWRRAGGGLIGRkgyiGPLGKGDTMMCAVYGWTEEMAFSGTSTGDVCIW--KDIFLIKTVK 900
           ************9978888887.9999***888887777789985556677899***********************..889******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
             h+++v s+   +  k +v+g++dg v lwd + ++c++t+  
   Q: 901  A-HDGPVFSMHALE--KGFVTGGKDGVVALWDDSFERCLKTYAI 941
           8.********9888..67**********************9965 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAARSAPNCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTISV LKDIHTHGIA CLSFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCC GGAGCGCCCC AAACTGCCAC CTGCGGCTGG AATGGGTGTA CGGCTACCGT 60
GGCCATCAGT GCCGCAACAA CCTCTACTAC ACCGCAGCCA AGGAGATCGT CTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	92.68	0.00e+00	3699.00
IUUC-Apl-003360	Anas platyrhynchos	92.42	0.00e+00	3581.00
IUUC-Ame-011681	Astyanax mexicanus	86.06	0.00e+00	3523.00
IUUC-Bta-012838	Bos taurus	92.32	0.00e+00	3728.00
IUUC-Cja-019068	Callithrix jacchus	93.02	0.00e+00	3721.00
IUUC-Cfa-020531	Canis familiaris	92.81	0.00e+00	3763.00
IUUC-Cpo-022304	Cavia porcellus	89.93	0.00e+00	3516.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.36	3.00e-102	368.00
IUUC-Csa-023621	Chlorocebus sabaeus	92.47	0.00e+00	3388.00
IUUC-Cho-024944	Choloepus hoffmanni	80.30	0.00e+00	1247.00
IUUC-Dre-028772	Danio rerio	85.46	0.00e+00	3511.00
IUUC-Dno-030063	Dasypus novemcinctus	91.47	0.00e+00	3679.00
IUUC-Dor-030980	Dipodomys ordii	83.96	0.00e+00	1542.00
IUUC-Ete-032554	Echinops telfairi	90.88	0.00e+00	1032.00
IUUC-Eca-033909	Equus caballus	93.08	0.00e+00	3442.00
IUUC-Eeu-035180	Erinaceus europaeus	76.38	0.00e+00	1397.00
IUUC-Fal-037219	Ficedula albicollis	92.74	0.00e+00	3704.00
IUUC-Gmo-039146	Gadus morhua	81.42	0.00e+00	3325.00
IUUC-Gga-041095	Gallus gallus	92.37	0.00e+00	2667.00
IUUC-Gac-041341	Gasterosteus aculeatus	83.96	0.00e+00	3409.00
IUUC-Hsa-045997	Homo sapiens	93.27	0.00e+00	3729.00
IUUC-Lch-050306	Latimeria chalumnae	85.33	0.00e+00	3202.00
IUUC-Loc-052215	Lepisosteus oculatus	86.13	0.00e+00	3560.00
IUUC-Laf-054044	Loxodonta africana	91.67	0.00e+00	3700.00
IUUC-Mcc-054733	Macaca mulatta	93.17	0.00e+00	3724.00
IUUC-Meu-055977	Macropus eugenii	95.16	0.00e+00	1092.00
IUUC-Mga-059666	Meleagris gallopavo	91.45	0.00e+00	3539.00
IUUC-Mmr-060995	Microcebus murinus	93.27	0.00e+00	3735.00
IUUC-Mmu-063533	Mus musculus	92.11	0.00e+00	3679.00
IUUC-Mpu-066704	Mustela putorius furo	92.92	0.00e+00	3753.00
IUUC-Mlu-067592	Myotis lucifugus	92.11	0.00e+00	3700.00
IUUC-Nle-069911	Nomascus leucogenys	93.22	0.00e+00	3721.00
IUUC-Ont-071966	Oreochromis niloticus	85.69	0.00e+00	3523.00
IUUC-Ola-086738	Oryzias latipes	84.95	0.00e+00	3471.00
IUUC-Oga-088436	Otolemur garnettii	91.07	0.00e+00	3644.00
IUUC-Oar-090153	Ovis aries	92.17	0.00e+00	3591.00
IUUC-Ptr-091008	Pan troglodytes	92.97	0.00e+00	3705.00
IUUC-Pan-092404	Papio anubis	93.06	0.00e+00	3712.00
IUUC-Psi-093417	Pelodiscus sinensis	91.59	0.00e+00	3553.00
IUUC-Pfo-096073	Poecilia formosa	85.51	0.00e+00	3516.00
IUUC-Pab-097900	Pongo abelii	92.82	0.00e+00	3711.00
IUUC-Pva-102880	Pteropus vampyrus	88.95	0.00e+00	3391.00
IUUC-Rno-106084	Rattus norvegicus	92.26	0.00e+00	3741.00
IUUC-Sha-106974	Sarcophilus harrisii	96.71	0.00e+00	3849.00
IUUC-Sar-113401	Sorex araneus	84.08	0.00e+00	934.00
IUUC-Ssc-116057	Sus scrofa	92.14	0.00e+00	3633.00
IUUC-Tru-118444	Takifugu rubripes	84.44	0.00e+00	3439.00
IUUC-Tsy-118941	Tarsius syrichta	81.88	0.00e+00	2740.00
IUUC-Tni-120683	Tetraodon nigroviridis	83.87	0.00e+00	3284.00
IUUC-Tbe-127467	Tupaia belangeri	84.72	0.00e+00	1773.00
IUUC-Ttr-129138	Tursiops truncatus	88.84	0.00e+00	3410.00
IUUC-Vpa-130083	Vicugna pacos	87.05	0.00e+00	3317.00
IUUC-Xtr-131835	Xenopus tropicalis	88.59	0.00e+00	3636.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence