iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091008

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03095988

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006609.5	ENSPTRT00000012142.5	ENSPTRP00000011247.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-55	181.5	1700	1732
UBD/Beta-Prp	3.10e-131	437.0	726	941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htd.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           H d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1700 HVDgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1732
           5553699999898889***************75 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg..heaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           h++ i c++++p k+++atg  +rd +i +wd++t k l+ l+g  h+ +v+av+fs dgk l++++ D  +t+ +wd ++g+ +++ +
   Q: 726  HDDDILCLTIHPLKDYVATGqvGRDPSIHIWDTETIKPLSILKGghHQYGVSAVDFSADGKRLASVGIDdsHTVVLWDWKKGEKLSIAR 814
           4555566************95569******************65337889***************9999999***************** PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           g +d++  ++++p+  dkl++++  +  + w    g  +         g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t 
   Q: 815  GSKDKIFVVKMNPYVpDKLITAG-IKHMKFWRKAGGGLIGRkgyiGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDIFLVKTV 900
           *************9978888887.9999***88888888779998455677799************************..889****** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           +  h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 901  KA-HDGPVFSMHALE--KGFVTGGKDGIVALWDDSFERCLKTYA 941
           98.********9888..67**********************996 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICIW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGGCATCC ACTTGACAGC CGGCGGCGCT CGCGGCCCTC AGCATGTTCC GCGAGGCGAG 60
GGTTTCCTCC CCCCTGTGGG CTGAGGCGGC GGCGGCCCCC GAAACGAGAT GCACCTGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011041--Quinoprot_gluc/sorb_DH
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0015630--C:microtubule cytoskeleton
GO:0003824--F:catalytic activity
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	96.16	0.00e+00	3820.00
IUUC-Apl-003360	Anas platyrhynchos	90.87	0.00e+00	3536.00
IUUC-Ame-011681	Astyanax mexicanus	84.67	0.00e+00	3486.00
IUUC-Bta-012838	Bos taurus	96.06	0.00e+00	3857.00
IUUC-Cja-019068	Callithrix jacchus	98.53	0.00e+00	3906.00
IUUC-Cfa-020531	Canis familiaris	96.16	0.00e+00	3881.00
IUUC-Cpo-022304	Cavia porcellus	92.75	0.00e+00	3608.00
IUUC-Csa-023621	Chlorocebus sabaeus	98.31	0.00e+00	3576.00
IUUC-Cho-024944	Choloepus hoffmanni	76.97	0.00e+00	1499.00
IUUC-Cin-025205	Ciona intestinalis	57.88	0.00e+00	2397.00
IUUC-Csv-026014	Ciona savignyi	58.33	0.00e+00	2385.00
IUUC-Dre-028772	Danio rerio	84.43	0.00e+00	3485.00
IUUC-Dno-030063	Dasypus novemcinctus	95.01	0.00e+00	3804.00
IUUC-Dor-030980	Dipodomys ordii	86.99	0.00e+00	1578.00
IUUC-Ete-032554	Echinops telfairi	93.21	0.00e+00	1045.00
IUUC-Eca-033909	Equus caballus	96.68	0.00e+00	3561.00
IUUC-Eeu-035180	Erinaceus europaeus	86.71	0.00e+00	1203.00
IUUC-Fal-037219	Ficedula albicollis	91.29	0.00e+00	3662.00
IUUC-Gmo-039146	Gadus morhua	80.24	0.00e+00	3288.00
IUUC-Gga-041095	Gallus gallus	90.73	0.00e+00	2641.00
IUUC-Gac-041341	Gasterosteus aculeatus	82.12	0.00e+00	3379.00
IUUC-Hsa-045997	Homo sapiens	99.70	0.00e+00	3937.00
IUUC-Lch-050306	Latimeria chalumnae	84.37	0.00e+00	3158.00
IUUC-Loc-052215	Lepisosteus oculatus	84.88	0.00e+00	3534.00
IUUC-Laf-054044	Loxodonta africana	95.15	0.00e+00	3823.00
IUUC-Mcc-054733	Macaca mulatta	99.09	0.00e+00	3916.00
IUUC-Mga-059666	Meleagris gallopavo	89.63	0.00e+00	3492.00
IUUC-Mmr-060995	Microcebus murinus	97.63	0.00e+00	3876.00
IUUC-Mdo-062482	Monodelphis domestica	92.97	0.00e+00	3751.00
IUUC-Mmu-063533	Mus musculus	95.50	0.00e+00	3797.00
IUUC-Mpu-066704	Mustela putorius furo	96.16	0.00e+00	3870.00
IUUC-Mlu-067592	Myotis lucifugus	95.75	0.00e+00	3821.00
IUUC-Nle-069911	Nomascus leucogenys	98.89	0.00e+00	3907.00
IUUC-Ont-071966	Oreochromis niloticus	84.41	0.00e+00	3486.00
IUUC-Ola-086738	Oryzias latipes	83.76	0.00e+00	3437.00
IUUC-Oga-088436	Otolemur garnettii	94.81	0.00e+00	3781.00
IUUC-Oar-090153	Ovis aries	95.67	0.00e+00	3710.00
IUUC-Pan-092404	Papio anubis	98.63	0.00e+00	3893.00
IUUC-Psi-093417	Pelodiscus sinensis	90.45	0.00e+00	3521.00
IUUC-Pfo-096073	Poecilia formosa	84.63	0.00e+00	3496.00
IUUC-Pab-097900	Pongo abelii	98.89	0.00e+00	3907.00
IUUC-Pca-100107	Procavia capensis	80.10	0.00e+00	2532.00
IUUC-Pva-102880	Pteropus vampyrus	92.16	0.00e+00	3497.00
IUUC-Rno-106084	Rattus norvegicus	95.60	0.00e+00	3867.00
IUUC-Sha-106974	Sarcophilus harrisii	92.79	0.00e+00	3746.00
IUUC-Sar-113401	Sorex araneus	84.45	0.00e+00	1814.00
IUUC-Ssc-116057	Sus scrofa	95.99	0.00e+00	3763.00
IUUC-Tru-118444	Takifugu rubripes	82.45	0.00e+00	3405.00
IUUC-Tsy-118941	Tarsius syrichta	85.28	0.00e+00	2845.00
IUUC-Tni-120683	Tetraodon nigroviridis	82.03	0.00e+00	3254.00
IUUC-Tbe-127467	Tupaia belangeri	88.64	0.00e+00	1852.00
IUUC-Ttr-129138	Tursiops truncatus	91.84	0.00e+00	3516.00
IUUC-Vpa-130083	Vicugna pacos	90.53	0.00e+00	3430.00
IUUC-Xtr-131835	Xenopus tropicalis	88.55	0.00e+00	3637.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence