iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-31	106.6	702	735
UBD/Beta-Prp	8.00e-66	222.6	73	210

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH++ vt+++f +d ++l+s s+D  i vW+l++
   Q: 702  GHSEIVTGMKFsNDcKHLISVSGDSCIFVWRLSS 735
           8***********999****************865 PP

UBD/Beta-Prp

   S: 34   ikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGs..hdrti 118
           + +++ ++ k  + l +  +++ta+ fspdgk+lvtg +    +++vwd+  + +v  l++h++ v +++fsps +++vs +  hd ++
   Q: 73   VVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGhmPAVRVWDVAERNQVAELQEHKYGVACVAFSPSAKYIVSVGyqHDMIV 161
           467888888999999*************************8889***********************************98555999** PP
   S: 119  rvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...k 167
           +vw ++++ ++    ++ ++ v+ v++++d++++v++++ r +++W l   k
   Q: 162  NVWAWKKNIVVA--SNKVSSRVTAVSFSEDCSYFVTAGN-RHIKFWYLddsK 210
           ***********6..999999****************985.889999874443 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MMAGEGSTIT SRIKNLLRSP SIKLRRSKAG NRREDLSSKV TLEKVLGVTV SGGRGLACDP 60
RSGLVAYPAG CVVVLFNPRK HKQHHILNSS RKTITALAFS PDGKYLVTGE SGHMPAVRVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGCTCCCA AGACTGGGGT GTGGGAGGGA GGCTCTCGCA TTGGATCGGG CCAGCGCGAG 60
CCCGGCGGCC ACCGCGGTGC TTCGGCCCCT TGCCCGGTGG CTTCGGAGGC CTCCTCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0016301--F:kinase activity
GO:0008380--P:RNA splicing

KEGG

rno:362197

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001604	Ailuropoda melanoleuca	86.53	0.00e+00	2396.00
IUUC-Apl-003236	Anas platyrhynchos	63.65	0.00e+00	1730.00
IUUC-Aca-004486	Anolis carolinensis	63.02	0.00e+00	1619.00
IUUC-Aly-006434	Arabidopsis lyrata	30.93	1.00e-57	218.00
IUUC-Ath-007624	Arabidopsis thaliana	30.58	5.00e-92	332.00
IUUC-Ago-007823	Ashbya gossypii	33.33	2.00e-15	78.60
IUUC-Acl-008257	Aspergillus clavatus	22.94	5.00e-30	127.00
IUUC-Ang-009797	Aspergillus niger	26.47	3.00e-15	77.80
IUUC-Ame-011306	Astyanax mexicanus	50.61	0.00e+00	1313.00
IUUC-Bgr-012083	Blumeria graminis	24.46	2.00e-32	135.00
IUUC-Bta-013041	Bos taurus	86.16	0.00e+00	2388.00
IUUC-Bci-013828	Botrytis cinerea	25.14	4.00e-38	153.00
IUUC-Bol-016347	Brassica oleracea	31.12	4.00e-90	326.00
IUUC-Bra-017959	Brassica rapa	31.12	9.00e-93	335.00
IUUC-Cel-018592	Caenorhabditis elegans	29.22	2.00e-73	271.00
IUUC-Cja-018986	Callithrix jacchus	85.55	0.00e+00	2408.00
IUUC-Cfa-020896	Canis familiaris	86.90	0.00e+00	2413.00
IUUC-Cpo-021348	Cavia porcellus	85.09	0.00e+00	2420.00
IUUC-Csa-023118	Chlorocebus sabaeus	86.14	0.00e+00	2306.00
IUUC-Csv-026079	Ciona savignyi	41.78	7.00e-81	293.00
IUUC-Dre-027495	Danio rerio	56.85	0.00e+00	1276.00
IUUC-Dno-029772	Dasypus novemcinctus	83.95	0.00e+00	2420.00
IUUC-Dor-030615	Dipodomys ordii	85.89	0.00e+00	2188.00
IUUC-Dme-032179	Drosophila melanogaster	50.96	0.00e+00	782.00
IUUC-Ete-033108	Echinops telfairi	88.53	0.00e+00	1645.00
IUUC-Eca-033836	Equus caballus	86.44	0.00e+00	2370.00
IUUC-Eeu-035189	Erinaceus europaeus	75.23	0.00e+00	2060.00
IUUC-Fca-036471	Felis catus	86.48	0.00e+00	2435.00
IUUC-Fal-037354	Ficedula albicollis	59.47	0.00e+00	1721.00
IUUC-Fox-037952	Fusarium oxysporum	22.66	1.00e-30	128.00
IUUC-Gmo-039644	Gadus morhua	61.96	0.00e+00	876.00
IUUC-Ggr-039729	Gaeumannomyces graminis	23.96	9.00e-27	115.00
IUUC-Gga-040202	Gallus gallus	81.45	1.00e-158	552.00
IUUC-Gac-042193	Gasterosteus aculeatus	49.49	0.00e+00	1040.00
IUUC-Ggo-045532	Gorilla gorilla	84.95	0.00e+00	2238.00
IUUC-Hsa-046352	Homo sapiens	85.81	0.00e+00	2270.00
IUUC-Itr-048210	Ictidomys tridecemlineatus	87.24	0.00e+00	2420.00
IUUC-Kpa-049269	Komagataella pastoris	25.43	1.00e-16	82.00
IUUC-Lch-049450	Latimeria chalumnae	66.29	0.00e+00	1266.00
IUUC-Loc-052784	Lepisosteus oculatus	58.01	0.00e+00	1345.00
IUUC-Lma-053327	Leptosphaeria maculans	30.26	7.00e-21	96.30
IUUC-Laf-053885	Loxodonta africana	85.73	0.00e+00	2336.00
IUUC-Mcc-055747	Macaca mulatta	86.07	0.00e+00	2265.00
IUUC-Meu-056200	Macropus eugenii	75.78	0.00e+00	2055.00
IUUC-Mor-057027	Magnaporthe oryzae	22.24	2.00e-25	111.00
IUUC-Mga-059325	Meleagris gallopavo	61.63	0.00e+00	1666.00
IUUC-Mmr-061305	Microcebus murinus	87.88	0.00e+00	2331.00
IUUC-Mdo-063076	Monodelphis domestica	72.73	0.00e+00	1815.00
IUUC-Mmu-064319	Mus musculus	94.90	0.00e+00	2727.00
IUUC-Mpu-066443	Mustela putorius furo	85.75	0.00e+00	2414.00
IUUC-Mlu-068153	Myotis lucifugus	85.16	0.00e+00	2348.00
IUUC-Ncr-068758	Neurospora crassa	23.40	1.00e-30	128.00
IUUC-Nle-069578	Nomascus leucogenys	85.48	0.00e+00	2253.00
IUUC-Opr-070721	Ochotona princeps	85.28	0.00e+00	2294.00
IUUC-Ont-071411	Oreochromis niloticus	57.71	0.00e+00	1138.00
IUUC-Oan-073644	Ornithorhynchus anatinus	85.66	0.00e+00	1200.00
IUUC-Ocu-073900	Oryctolagus cuniculus	83.71	0.00e+00	2247.00
IUUC-Ola-087185	Oryzias latipes	60.14	0.00e+00	1165.00
IUUC-Oga-088733	Otolemur garnettii	85.92	0.00e+00	2282.00
IUUC-Oar-089569	Ovis aries	85.34	0.00e+00	2356.00
IUUC-Pan-092735	Papio anubis	86.14	0.00e+00	2368.00
IUUC-Psi-093457	Pelodiscus sinensis	73.11	0.00e+00	1598.00
IUUC-Pma-094285	Petromyzon marinus	64.91	0.00e+00	1029.00
IUUC-Pno-094837	Phaeosphaeria nodorum	30.88	2.00e-20	94.70
IUUC-Ppa-095596	Physcomitrella patens	38.02	7.00e-142	498.00
IUUC-Pfo-096375	Poecilia formosa	67.20	0.00e+00	1004.00
IUUC-Pab-098737	Pongo abelii	86.13	0.00e+00	2288.00
IUUC-Pca-100959	Procavia capensis	81.28	0.00e+00	1664.00
IUUC-Pva-102929	Pteropus vampyrus	83.04	0.00e+00	2280.00
IUUC-Pte-104373	Pyrenophora teres	28.29	6.00e-17	83.60
IUUC-Sha-106946	Sarcophilus harrisii	77.66	0.00e+00	2008.00
IUUC-Ssl-108471	Sclerotinia sclerotiorum	25.71	7.00e-33	136.00
IUUC-Sly-110969	Solanum lycopersicum	31.21	6.00e-91	328.00
IUUC-Stu-112838	Solanum tuberosum	32.29	4.00e-55	209.00
IUUC-Ssc-116302	Sus scrofa	86.10	0.00e+00	2409.00
IUUC-Tgu-117055	Taeniopygia guttata	71.24	0.00e+00	1483.00
IUUC-Tru-118066	Takifugu rubripes	53.82	0.00e+00	1130.00
IUUC-Tsy-119530	Tarsius syrichta	96.72	0.00e+00	696.00
IUUC-Tbe-128005	Tupaia belangeri	85.06	0.00e+00	1739.00
IUUC-Ttr-128385	Tursiops truncatus	79.46	0.00e+00	2174.00
IUUC-Xtr-132966	Xenopus tropicalis	58.19	0.00e+00	1512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence