iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061901

Ensembl Protein ID

ENSMODP00000019199.4

UniProt Accession

F6WH28; F6WH28_MONDO

Protein Name

Uncharacterized protein

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015376.4	ENSMODT00000019546.4	ENSMODP00000019199.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.60e-30	101.8	603	635
UBD/Beta-Prp	1.50e-45	155.8	597	813

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+     +l+s+s Dgt+++W+++
   Q: 603  GHTDAVWGLAYsgVHQRLLSCSADGTLRLWNTT 635
           8**********652289**************76 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls......lsfspsgdklvsGshdrtirvwdletg 126
           l   l gh+++v+ + +s   + l+++s D+t+++w+     +  ++ + ++++        +s++p  +++v+  +  +  ++++et+
   Q: 597  LRGALLGHTDAVWGLAYSGVHQRLLSCSADGTLRLWNTTEIAPALSVFNDNQELGIpasvdlVSSDP--SHMVASFNNGYTSIFNMETQ 683
           44568*******************************8887776666665666555433311166666..99999999************ PP
   S: 127  qclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           q + +      t s+ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l
   Q: 684  QRILTleanldTTSNISCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNL 771
           ****9***9999999999999999***99**************************98.******************************* PP
   S: 210  qtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 772  ESKTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 813
           *************999999******************97655 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDEQAGPGVF FSNSHPAAAG GVKGLGPLAE AAAAAAGDGA AAAAAVAAAG AARAQYSLPG 60
ILHFLQHEWA RFEVERAQWE VERAELQAQI AFLQGERKGQ ENLKKDLVRR IKMLEYALKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTGTTTT TTTAAATAAA ATTCATGGAG TTGGGTACAA AGGGAGTGGT CCTAAGACAA 60
ATTCTTTTGG AGAAACTTTT GCCTATTATG GGGACCAGCC TTCGAACAGG CTAGATATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	89.66	0.00e+00	1292.00
IUUC-Apl-003927	Anas platyrhynchos	85.15	0.00e+00	1115.00
IUUC-Aca-004933	Anolis carolinensis	86.52	0.00e+00	1221.00
IUUC-Ame-010997	Astyanax mexicanus	69.47	0.00e+00	1040.00
IUUC-Bta-013077	Bos taurus	86.92	0.00e+00	1301.00
IUUC-Cja-018973	Callithrix jacchus	87.29	0.00e+00	1310.00
IUUC-Cfa-020988	Canis familiaris	85.52	0.00e+00	1160.00
IUUC-Cpo-022496	Cavia porcellus	87.29	0.00e+00	1315.00
IUUC-Csa-023829	Chlorocebus sabaeus	87.29	0.00e+00	1308.00
IUUC-Dre-028560	Danio rerio	65.43	0.00e+00	953.00
IUUC-Dor-030721	Dipodomys ordii	79.34	0.00e+00	1169.00
IUUC-Ete-033074	Echinops telfairi	74.32	3.00e-149	522.00
IUUC-Eca-033760	Equus caballus	88.80	0.00e+00	1212.00
IUUC-Eeu-034953	Erinaceus europaeus	94.79	0.00e+00	743.00
IUUC-Fca-036530	Felis catus	88.80	0.00e+00	1219.00
IUUC-Fal-037353	Ficedula albicollis	88.43	0.00e+00	952.00
IUUC-Gmo-039094	Gadus morhua	68.53	0.00e+00	658.00
IUUC-Gga-040132	Gallus gallus	84.95	0.00e+00	1129.00
IUUC-Gac-041713	Gasterosteus aculeatus	69.39	0.00e+00	1040.00
IUUC-Ggo-045455	Gorilla gorilla	76.89	0.00e+00	1106.00
IUUC-Hsa-046415	Homo sapiens	86.67	0.00e+00	1303.00
IUUC-Lch-050475	Latimeria chalumnae	78.66	0.00e+00	1183.00
IUUC-Loc-051859	Lepisosteus oculatus	73.19	0.00e+00	1111.00
IUUC-Laf-053537	Loxodonta africana	87.53	0.00e+00	1316.00
IUUC-Mcc-055817	Macaca mulatta	87.78	0.00e+00	1308.00
IUUC-Meu-055946	Macropus eugenii	70.55	0.00e+00	929.00
IUUC-Mga-059694	Meleagris gallopavo	84.86	0.00e+00	1106.00
IUUC-Mmr-060768	Microcebus murinus	88.14	0.00e+00	1323.00
IUUC-Mmu-064154	Mus musculus	85.45	0.00e+00	1288.00
IUUC-Mpu-065827	Mustela putorius furo	90.22	0.00e+00	1370.00
IUUC-Mlu-067102	Myotis lucifugus	89.66	0.00e+00	1279.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	89.07	0.00e+00	1221.00
IUUC-Ont-072025	Oreochromis niloticus	69.69	0.00e+00	1031.00
IUUC-Oan-072950	Ornithorhynchus anatinus	89.10	0.00e+00	1164.00
IUUC-Ocu-074316	Oryctolagus cuniculus	88.80	0.00e+00	1202.00
IUUC-Ola-087279	Oryzias latipes	67.96	0.00e+00	1018.00
IUUC-Oga-088284	Otolemur garnettii	86.92	0.00e+00	1308.00
IUUC-Oar-090304	Ovis aries	87.29	0.00e+00	1307.00
IUUC-Ptr-091052	Pan troglodytes	86.80	0.00e+00	1306.00
IUUC-Pan-092270	Papio anubis	83.94	0.00e+00	1270.00
IUUC-Psi-093907	Pelodiscus sinensis	84.42	0.00e+00	1026.00
IUUC-Pfo-097042	Poecilia formosa	70.41	0.00e+00	1122.00
IUUC-Pab-098110	Pongo abelii	86.80	0.00e+00	1306.00
IUUC-Pca-100266	Procavia capensis	76.08	0.00e+00	922.00
IUUC-Pva-102824	Pteropus vampyrus	85.21	0.00e+00	1275.00
IUUC-Pgr-103483	Puccinia graminis	36.71	2.00e-56	215.00
IUUC-Rno-105638	Rattus norvegicus	85.82	0.00e+00	1297.00
IUUC-Sha-107004	Sarcophilus harrisii	88.96	0.00e+00	1152.00
IUUC-Sre-115115	Sporisorium reilianum	33.59	2.00e-64	241.00
IUUC-Ssc-115280	Sus scrofa	87.53	0.00e+00	1318.00
IUUC-Tgu-116759	Taeniopygia guttata	84.99	0.00e+00	1127.00
IUUC-Tru-117944	Takifugu rubripes	69.44	0.00e+00	1035.00
IUUC-Tsy-119405	Tarsius syrichta	79.07	0.00e+00	1013.00
IUUC-Tni-120571	Tetraodon nigroviridis	68.92	0.00e+00	1038.00
IUUC-Vpa-130294	Vicugna pacos	88.89	0.00e+00	1211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence