iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066448

Ensembl Protein ID

ENSMPUP00000010480.1

UniProt Accession

M3YGM3; M3YGM3_MUSPF

Genbank Protein ID

ENSMPUP00000010480

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01041115

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010558.1	ENSMPUT00000010649.1	ENSMPUP00000010480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-32	107.7	1531	1565
UBD/Beta-Prp	3.80e-42	144.5	1398	1601

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1531 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1565
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ +sp+g +++ +++ +++++w+ls +++v +l+gh   v++l++ +   + d +v+Gs+d ++++++l  g+c+     
   Q: 1398 GEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQtasQHDLVVTGSKDHYVKMFEL--GECVTGtig 1481
           56789********9.9999**********************************998556***************65..667766779 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + 
   Q: 1482 pthnFEPPHYDGIECLAIQG--DVLFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFTP 1566
           9999999************9..9*************************999************************************ PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + + +gh+++++ + +    +++ ++ssD  +++W++
   Q: 1567 IGEIRGHDSPINAICTN--AKHIFTASSDCRVKVWNY 1601
           ************77777..****************96 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ 60
EQIYSTCVSK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG FDTVTSEEEQ GIIPRAIAHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NCGCAGCCGC TGCCGCTGCC TGGGGCATCG GCCCCCAGAC CCCCGCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	96.60	0.00e+00	2835.00
IUUC-Apl-003204	Anas platyrhynchos	75.50	0.00e+00	1572.00
IUUC-Aca-004506	Anolis carolinensis	80.65	0.00e+00	1623.00
IUUC-Ame-011515	Astyanax mexicanus	74.78	0.00e+00	1454.00
IUUC-Bta-013185	Bos taurus	75.79	0.00e+00	2161.00
IUUC-Cja-018844	Callithrix jacchus	92.33	0.00e+00	2804.00
IUUC-Cfa-021187	Canis familiaris	97.50	0.00e+00	2906.00
IUUC-Cpo-022444	Cavia porcellus	92.98	0.00e+00	2827.00
IUUC-Csa-023852	Chlorocebus sabaeus	96.27	0.00e+00	2883.00
IUUC-Csv-026158	Ciona savignyi	59.55	2.00e-178	620.00
IUUC-Dre-027839	Danio rerio	74.40	0.00e+00	1439.00
IUUC-Dno-030058	Dasypus novemcinctus	92.31	0.00e+00	2758.00
IUUC-Dor-030673	Dipodomys ordii	91.26	0.00e+00	2672.00
IUUC-Ete-032705	Echinops telfairi	82.99	0.00e+00	902.00
IUUC-Eca-033885	Equus caballus	94.89	0.00e+00	2789.00
IUUC-Eeu-035338	Erinaceus europaeus	81.36	0.00e+00	2183.00
IUUC-Fca-035388	Felis catus	97.66	0.00e+00	2714.00
IUUC-Fal-037044	Ficedula albicollis	86.77	0.00e+00	2681.00
IUUC-Gmo-039034	Gadus morhua	77.10	0.00e+00	756.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.38	0.00e+00	2278.00
IUUC-Ggo-045392	Gorilla gorilla	95.74	0.00e+00	2867.00
IUUC-Hsa-046713	Homo sapiens	96.33	0.00e+00	2886.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	94.78	0.00e+00	1664.00
IUUC-Loc-052703	Lepisosteus oculatus	78.89	0.00e+00	2495.00
IUUC-Laf-054193	Loxodonta africana	85.41	0.00e+00	2471.00
IUUC-Mcc-055484	Macaca mulatta	96.07	0.00e+00	2857.00
IUUC-Meu-056278	Macropus eugenii	82.91	0.00e+00	1195.00
IUUC-Mga-059816	Meleagris gallopavo	83.31	0.00e+00	2564.00
IUUC-Mmr-061071	Microcebus murinus	92.12	0.00e+00	2758.00
IUUC-Mdo-062845	Monodelphis domestica	90.17	0.00e+00	2774.00
IUUC-Mmu-063967	Mus musculus	94.63	0.00e+00	2813.00
IUUC-Nle-070037	Nomascus leucogenys	94.69	0.00e+00	2213.00
IUUC-Opr-070325	Ochotona princeps	91.60	0.00e+00	2657.00
IUUC-Ont-071851	Oreochromis niloticus	72.70	0.00e+00	2310.00
IUUC-Oan-073615	Ornithorhynchus anatinus	87.77	0.00e+00	2532.00
IUUC-Ocu-073855	Oryctolagus cuniculus	95.42	0.00e+00	2830.00
IUUC-Ola-086703	Oryzias latipes	71.41	0.00e+00	2279.00
IUUC-Oga-088171	Otolemur garnettii	93.19	0.00e+00	2784.00
IUUC-Oar-089693	Ovis aries	77.11	0.00e+00	1226.00
IUUC-Ptr-090535	Pan troglodytes	97.29	0.00e+00	1833.00
IUUC-Pan-091917	Papio anubis	96.03	0.00e+00	2654.00
IUUC-Psi-093752	Pelodiscus sinensis	76.88	0.00e+00	1394.00
IUUC-Pfo-096827	Poecilia formosa	69.26	0.00e+00	1349.00
IUUC-Pab-098441	Pongo abelii	96.33	0.00e+00	2899.00
IUUC-Pca-100781	Procavia capensis	96.25	0.00e+00	913.00
IUUC-Pva-103099	Pteropus vampyrus	89.58	0.00e+00	1344.00
IUUC-Rno-105872	Rattus norvegicus	93.96	0.00e+00	2858.00
IUUC-Sha-107097	Sarcophilus harrisii	88.58	0.00e+00	2628.00
IUUC-Ssc-115638	Sus scrofa	94.15	0.00e+00	2465.00
IUUC-Tgu-116504	Taeniopygia guttata	86.94	0.00e+00	1690.00
IUUC-Tru-118242	Takifugu rubripes	72.96	0.00e+00	1481.00
IUUC-Ttr-128824	Tursiops truncatus	88.63	0.00e+00	2247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence