iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117758

Ensembl Protein ID

ENSTRUP00000031857.1

UniProt Accession

H2U4J5; H2U4J5_TAKRU

Protein Name

Uncharacterized protein

Gene Name

trioa; trio

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012584.1	ENSTRUT00000031978.1	ENSTRUP00000031855.1
ENSTRUG00000012584.1	ENSTRUT00000031979.1	ENSTRUP00000031856.1
ENSTRUG00000012584.1	ENSTRUT00000031980.1	ENSTRUP00000031857.1
ENSTRUG00000012584.1	ENSTRUT00000031981.1	ENSTRUP00000031858.1
ENSTRUG00000012584.1	ENSTRUT00000031982.1	ENSTRUP00000031859.1
ENSTRUG00000012584.1	ENSTRUT00000031983.1	ENSTRUP00000031860.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-10	42.6	1616	1667

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a+n++eLt ++G +v+v+e  ++  +W+           +Gl+P
   Q: 1616 TVVIHDFMASNSNELTVRRGQTVEVLERCHERPDWCLVRTtdRSPALEGLVP 1667
           679***********************9999999**97654223334567776 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MRAMEVLPIL KEKVAFLSGG RDRRGGPVLT FPSRSNHDRI RSDDLRRLIA YLAGIPSEEV 60
CKHGFTVIVD MRGSKWDSIK PLLKILQESF PSCIHVALII KPDNFWQKQR TNFGSSKFEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACTCAGTC TTCCATTCTT CTCTCTTACT CCAGGTTTCA GGAGAAATGA GGAGATGAGA 60
GCGATGGAAG TGCTTCCCAT CCTAAAAGAA AAAGTTGCCT TTTTGTCAGG TAAGTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	87.71	0.00e+00	3933.00
IUUC-Apl-003498	Anas platyrhynchos	87.57	0.00e+00	3924.00
IUUC-Bta-013121	Bos taurus	86.53	0.00e+00	3880.00
IUUC-Cja-018919	Callithrix jacchus	87.72	0.00e+00	3947.00
IUUC-Cfa-020547	Canis familiaris	87.72	0.00e+00	3942.00
IUUC-Cpo-022301	Cavia porcellus	79.36	0.00e+00	4736.00
IUUC-Csa-023889	Chlorocebus sabaeus	87.77	0.00e+00	3946.00
IUUC-Dre-028386	Danio rerio	91.83	0.00e+00	4072.00
IUUC-Dno-028888	Dasypus novemcinctus	87.33	0.00e+00	3910.00
IUUC-Dor-030992	Dipodomys ordii	81.01	0.00e+00	3567.00
IUUC-Ete-033167	Echinops telfairi	80.28	0.00e+00	1490.00
IUUC-Eca-033685	Equus caballus	87.26	0.00e+00	3919.00
IUUC-Fca-035647	Felis catus	86.67	0.00e+00	3925.00
IUUC-Fal-036845	Ficedula albicollis	87.99	0.00e+00	3956.00
IUUC-Gga-040959	Gallus gallus	88.08	0.00e+00	3965.00
IUUC-Gac-041349	Gasterosteus aculeatus	93.34	0.00e+00	4092.00
IUUC-Ggo-045170	Gorilla gorilla	87.75	0.00e+00	3927.00
IUUC-Hsa-046059	Homo sapiens	87.72	0.00e+00	3945.00
IUUC-Lch-050010	Latimeria chalumnae	85.71	0.00e+00	3806.00
IUUC-Loc-052783	Lepisosteus oculatus	81.51	0.00e+00	4850.00
IUUC-Laf-053884	Loxodonta africana	87.62	0.00e+00	3937.00
IUUC-Mcc-055804	Macaca mulatta	87.44	0.00e+00	3936.00
IUUC-Mga-060008	Meleagris gallopavo	79.82	0.00e+00	4774.00
IUUC-Mmr-061081	Microcebus murinus	87.77	0.00e+00	3944.00
IUUC-Mdo-062888	Monodelphis domestica	88.74	0.00e+00	3648.00
IUUC-Mmu-063327	Mus musculus	79.15	0.00e+00	4684.00
IUUC-Mpu-066905	Mustela putorius furo	87.68	0.00e+00	3940.00
IUUC-Mlu-068215	Myotis lucifugus	84.97	0.00e+00	3863.00
IUUC-Nle-069414	Nomascus leucogenys	85.82	0.00e+00	3828.00
IUUC-Opr-070819	Ochotona princeps	83.27	0.00e+00	3795.00
IUUC-Ont-072678	Oreochromis niloticus	95.60	0.00e+00	4180.00
IUUC-Oan-072974	Ornithorhynchus anatinus	87.77	0.00e+00	3947.00
IUUC-Ocu-074919	Oryctolagus cuniculus	79.99	0.00e+00	4737.00
IUUC-Oga-088068	Otolemur garnettii	87.77	0.00e+00	3948.00
IUUC-Oar-090050	Ovis aries	84.52	0.00e+00	3803.00
IUUC-Ptr-090841	Pan troglodytes	87.77	0.00e+00	3950.00
IUUC-Psi-093088	Pelodiscus sinensis	79.32	0.00e+00	4737.00
IUUC-Pfo-097201	Poecilia formosa	86.93	0.00e+00	3863.00
IUUC-Pab-098130	Pongo abelii	87.81	0.00e+00	3948.00
IUUC-Pca-100839	Procavia capensis	74.17	0.00e+00	3138.00
IUUC-Pva-102115	Pteropus vampyrus	86.72	0.00e+00	2670.00
IUUC-Rno-105207	Rattus norvegicus	79.06	0.00e+00	4677.00
IUUC-Sha-107011	Sarcophilus harrisii	75.40	0.00e+00	3586.00
IUUC-Tgu-116970	Taeniopygia guttata	79.25	0.00e+00	4736.00
IUUC-Ttr-128857	Tursiops truncatus	79.74	0.00e+00	3554.00
IUUC-Xtr-131909	Xenopus tropicalis	76.62	0.00e+00	4586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence