iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097854

Ensembl Protein ID

ENSPPYP00000000382.2

UniProt Accession

H2N451; H2N451_PONAB

Genbank Protein ID

ENSPPYP00000000382

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01056140

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000346.2	ENSPPYT00000000400.2	ENSPPYP00000000382.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.60e-13	49.2	311	357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 311  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 357
           8********988.6*******************.*******7.******5 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MEAATGLHPG PRPALPLGGP GPLGEFLPPP ECPVFEPSWE EFADPFAFIH KIRPIAEQTG 60
ICKVRPPPDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGAGGCG CACGGCGTGG GCTTGCGGCT AGACGTCGTC GTCGGAGGCT GAAAAAGCCC 60
AAGGTGCTGC CGCTGCTCGT ACAACTCGGA CTTGNNNNNN NNNNTCGTCG GAGGCTGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001963	Ailuropoda melanoleuca	93.73	0.00e+00	2097.00
IUUC-Apl-003770	Anas platyrhynchos	83.08	0.00e+00	1882.00
IUUC-Aca-004867	Anolis carolinensis	81.98	0.00e+00	1947.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	4.00e-09	58.50
IUUC-Ame-010620	Astyanax mexicanus	56.27	0.00e+00	1629.00
IUUC-Bta-012733	Bos taurus	90.57	0.00e+00	2043.00
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	95.05	0.00e+00	2217.00
IUUC-Cfa-021015	Canis familiaris	93.82	0.00e+00	2087.00
IUUC-Cpo-022340	Cavia porcellus	93.46	0.00e+00	2056.00
IUUC-Cre-022637	Chlamydomonas reinhardtii	48.21	2.00e-08	50.10
IUUC-Csa-023441	Chlorocebus sabaeus	95.84	0.00e+00	2211.00
IUUC-Cho-024823	Choloepus hoffmanni	93.76	0.00e+00	1610.00
IUUC-Dre-027707	Danio rerio	64.23	0.00e+00	1526.00
IUUC-Dno-028978	Dasypus novemcinctus	93.66	0.00e+00	2172.00
IUUC-Dor-030854	Dipodomys ordii	79.27	0.00e+00	1251.00
IUUC-Ete-032760	Echinops telfairi	90.54	0.00e+00	1477.00
IUUC-Eca-034370	Equus caballus	94.09	0.00e+00	2033.00
IUUC-Fca-035494	Felis catus	94.27	0.00e+00	2080.00
IUUC-Fal-037631	Ficedula albicollis	83.14	0.00e+00	1863.00
IUUC-Gmo-039522	Gadus morhua	64.16	0.00e+00	1493.00
IUUC-Gga-040802	Gallus gallus	83.87	0.00e+00	1992.00
IUUC-Gac-041563	Gasterosteus aculeatus	64.28	0.00e+00	1489.00
IUUC-Ggo-044856	Gorilla gorilla	75.52	0.00e+00	1598.00
IUUC-Hsa-045888	Homo sapiens	93.03	0.00e+00	2219.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	8.00e-16	79.30
IUUC-Itr-048297	Ictidomys tridecemlineatus	94.28	0.00e+00	2154.00
IUUC-Lch-050483	Latimeria chalumnae	67.97	0.00e+00	1602.00
IUUC-Loc-052550	Lepisosteus oculatus	74.20	0.00e+00	1746.00
IUUC-Laf-053761	Loxodonta africana	91.13	0.00e+00	2038.00
IUUC-Mcc-055505	Macaca mulatta	92.94	0.00e+00	2216.00
IUUC-Meu-056467	Macropus eugenii	88.32	0.00e+00	1052.00
IUUC-Mga-059358	Meleagris gallopavo	83.11	0.00e+00	1882.00
IUUC-Mmr-060863	Microcebus murinus	94.11	0.00e+00	2175.00
IUUC-Mdo-061957	Monodelphis domestica	87.44	0.00e+00	2082.00
IUUC-Mmu-063944	Mus musculus	91.77	0.00e+00	2096.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	94.09	0.00e+00	2174.00
IUUC-Mlu-067366	Myotis lucifugus	86.57	0.00e+00	1982.00
IUUC-Nle-069256	Nomascus leucogenys	91.83	0.00e+00	2177.00
IUUC-Ont-071756	Oreochromis niloticus	64.60	0.00e+00	1508.00
IUUC-Oan-073568	Ornithorhynchus anatinus	88.06	0.00e+00	2071.00
IUUC-Ocu-073961	Oryctolagus cuniculus	93.48	0.00e+00	2165.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.40
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.60
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.40
IUUC-Ola-086448	Oryzias latipes	55.82	0.00e+00	1560.00
IUUC-Oga-088501	Otolemur garnettii	87.79	0.00e+00	1714.00
IUUC-Oar-090162	Ovis aries	89.95	0.00e+00	2032.00
IUUC-Ptr-090816	Pan troglodytes	93.19	0.00e+00	2227.00
IUUC-Pan-092764	Papio anubis	95.84	0.00e+00	2212.00
IUUC-Psi-093918	Pelodiscus sinensis	82.86	0.00e+00	1675.00
IUUC-Pfo-096672	Poecilia formosa	65.24	0.00e+00	1502.00
IUUC-Pca-100241	Procavia capensis	91.46	0.00e+00	1203.00
IUUC-Pva-103035	Pteropus vampyrus	84.23	0.00e+00	1829.00
IUUC-Rno-105574	Rattus norvegicus	89.85	0.00e+00	2048.00
IUUC-Sha-106552	Sarcophilus harrisii	87.40	0.00e+00	1049.00
IUUC-Sar-113477	Sorex araneus	90.14	0.00e+00	2055.00
IUUC-Ssc-116132	Sus scrofa	92.01	0.00e+00	2134.00
IUUC-Tgu-117452	Taeniopygia guttata	83.32	0.00e+00	1880.00
IUUC-Tru-117561	Takifugu rubripes	63.19	0.00e+00	1511.00
IUUC-Tsy-119271	Tarsius syrichta	91.39	0.00e+00	1516.00
IUUC-Tni-119650	Tetraodon nigroviridis	65.06	0.00e+00	1507.00
IUUC-Tbe-127890	Tupaia belangeri	88.56	0.00e+00	979.00
IUUC-Ttr-128546	Tursiops truncatus	91.15	0.00e+00	2028.00
IUUC-Vpa-130432	Vicugna pacos	84.95	0.00e+00	1136.00
IUUC-Xtr-132008	Xenopus tropicalis	72.71	0.00e+00	1694.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence