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Tag Content
UUCD2 ID IUUC-Aml-001666
UUCD1 version UUC-AiM-00010
Ensembl Protein ID ENSAMEP00000019139.1
UniProt Accession D2GXJ6; D2GXJ6_AILME
Genbank Protein ID EFB22557.1
Protein Name Putative uncharacterized protein
Genbank Nucleotide ID ACTA01000808
Gene Name HERC4; PANDA_001627
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000018102.1 ENSAMET00000019902.1 ENSAMEP00000019139.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 3.90e-101 338.9 733 1056
Active Site
Position(s) Description Evidence
1025 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           d kk l+v fvgE+++d+gGv +ef+ l+++el +p++g+f+y e+++  ++ +++      e  +lF+++G+++g+a+++  ++dl
   Q: 733  DYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTF-----EDSDLFHLIGVICGLAIYNFTIVDL 814
           78999***********************************************88877.....689********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll+kk sl+dl+e+ p++ +s+++++++ e+d+ee+ ++l+f+++ e++g t+++eL+ +G+++ V+++N++e+v+++
   Q: 815  HFPLALYKKLLKKKPSLDDLKELVPDVGRSMQQLLDYPEDDVEET-FCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY 900
           *************************************99999997.***************************************** PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y++++++++ ++af++Gf++v+  ++l+lF+++el+ ++ G++++d+++l+k+t+ykg+y +++p+i+ Fwev++e+  e++k+f
   Q: 901  VDYIFNKSVASLFDAFHAGFHKVCGGKVLQLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQF 987
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+++lk    vi+   + ++ lP s+TCfn+L+LP+Y++ke+l++kL+ Ai++++gF+l
   Q: 988  LLFLTGSDRIPILGMKSLK---LVIQStGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL 1056
           *******************...7777758889**************************************86 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MLCWGNASFG QLGLGGIDEE IVLEPRKSDF FINKKVRDVG CGLRHTVFVL DDGTVYTCGC 60
NDLGQLGHEK SRKKPEQVVA LDAQNIVAVS CGEAHTLALN DKGQVYAWGL DSDGQLGLLG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001666|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTTGTGCT GGGGAAATGC ATCCTTTGGA CAGCTAGGTT TGGGTGGAAT TGATGAAGAA 60
ATTGTACTAG AGCCCAGAAA AAGTGACTTT TTTATAAATA AAAAGGTCCG AGATGTGGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001666|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007283--P:spermatogenesis
KEGG aml:100479965
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003295 Anas platyrhynchos 88.47 0.00e+00 1877.00
IUUC-Aca-004336 Anolis carolinensis 86.04 0.00e+00 1824.00
IUUC-Ame-010768 Astyanax mexicanus 72.97 0.00e+00 1568.00
IUUC-Bta-013279 Bos taurus 98.58 0.00e+00 2019.00
IUUC-Cja-019023 Callithrix jacchus 97.92 0.00e+00 2005.00
IUUC-Cfa-021074 Canis familiaris 99.43 0.00e+00 2033.00
IUUC-Cpo-021461 Cavia porcellus 95.66 0.00e+00 1952.00
IUUC-Csa-024261 Chlorocebus sabaeus 98.30 0.00e+00 2016.00
IUUC-Cho-024513 Choloepus hoffmanni 77.96 0.00e+00 1488.00
IUUC-Cin-025232 Ciona intestinalis 42.82 0.00e+00 821.00
IUUC-Dre-028829 Danio rerio 74.62 0.00e+00 1565.00
IUUC-Dno-029445 Dasypus novemcinctus 94.93 0.00e+00 1626.00
IUUC-Dor-030158 Dipodomys ordii 96.70 0.00e+00 877.00
IUUC-Dme-032103 Drosophila melanogaster 44.97 0.00e+00 891.00
IUUC-Ete-033072 Echinops telfairi 86.75 0.00e+00 1726.00
IUUC-Eca-033317 Equus caballus 97.07 0.00e+00 1982.00
IUUC-Fca-035682 Felis catus 98.86 0.00e+00 2012.00
IUUC-Fal-036969 Ficedula albicollis 87.04 0.00e+00 1852.00
IUUC-Gmo-038671 Gadus morhua 73.75 0.00e+00 1568.00
IUUC-Gga-041174 Gallus gallus 88.17 0.00e+00 1876.00
IUUC-Gac-042600 Gasterosteus aculeatus 74.06 0.00e+00 1519.00
IUUC-Gma-043616 Glycine max 37.22 5.00e-52 198.00
IUUC-Ggo-044589 Gorilla gorilla 97.92 0.00e+00 2039.00
IUUC-Hsa-046772 Homo sapiens 97.92 0.00e+00 2038.00
IUUC-Lch-050147 Latimeria chalumnae 80.24 0.00e+00 1428.00
IUUC-Loc-052684 Lepisosteus oculatus 81.17 0.00e+00 1712.00
IUUC-Laf-053844 Loxodonta africana 97.45 0.00e+00 1999.00
IUUC-Mcc-055531 Macaca mulatta 96.02 0.00e+00 2000.00
IUUC-Mga-060151 Meleagris gallopavo 87.44 0.00e+00 1558.00
IUUC-Mmr-060954 Microcebus murinus 97.92 0.00e+00 2004.00
IUUC-Mdo-062246 Monodelphis domestica 92.46 0.00e+00 1778.00
IUUC-Mmu-063369 Mus musculus 96.12 0.00e+00 1982.00
IUUC-Mpu-065936 Mustela putorius furo 98.98 0.00e+00 1873.00
IUUC-Mlu-067326 Myotis lucifugus 97.73 0.00e+00 1969.00
IUUC-Nle-069453 Nomascus leucogenys 97.54 0.00e+00 1989.00
IUUC-Ont-071720 Oreochromis niloticus 74.81 0.00e+00 1576.00
IUUC-Oan-073464 Ornithorhynchus anatinus 92.97 0.00e+00 1802.00
IUUC-Ocu-074207 Oryctolagus cuniculus 95.65 0.00e+00 1848.00
IUUC-Ola-086762 Oryzias latipes 74.24 0.00e+00 1533.00
IUUC-Oga-088435 Otolemur garnettii 98.20 0.00e+00 2010.00
IUUC-Oar-089233 Ovis aries 98.58 0.00e+00 2019.00
IUUC-Ptr-091368 Pan troglodytes 98.11 0.00e+00 2041.00
IUUC-Pan-092300 Papio anubis 98.30 0.00e+00 2016.00
IUUC-Psi-093406 Pelodiscus sinensis 89.69 0.00e+00 1897.00
IUUC-Pma-094113 Petromyzon marinus 71.89 0.00e+00 1142.00
IUUC-Ppa-095354 Physcomitrella patens 32.66 9.00e-148 517.00
IUUC-Pfo-097021 Poecilia formosa 73.23 0.00e+00 1585.00
IUUC-Pab-098327 Pongo abelii 98.30 0.00e+00 2043.00
IUUC-Pca-101075 Procavia capensis 95.57 0.00e+00 815.00
IUUC-Pva-102909 Pteropus vampyrus 87.23 0.00e+00 1709.00
IUUC-Rno-105457 Rattus norvegicus 96.88 0.00e+00 2003.00
IUUC-Sha-106632 Sarcophilus harrisii 93.76 0.00e+00 1952.00
IUUC-Sar-113679 Sorex araneus 88.47 0.00e+00 1148.00
IUUC-Tgu-116849 Taeniopygia guttata 83.25 0.00e+00 1744.00
IUUC-Tru-118206 Takifugu rubripes 72.98 0.00e+00 1477.00
IUUC-Tsy-119521 Tarsius syrichta 83.44 0.00e+00 1607.00
IUUC-Tni-120233 Tetraodon nigroviridis 72.14 0.00e+00 1467.00
IUUC-Tbe-127941 Tupaia belangeri 80.82 0.00e+00 1368.00
IUUC-Ttr-128926 Tursiops truncatus 98.72 0.00e+00 1190.00
IUUC-Vpa-130448 Vicugna pacos 98.30 0.00e+00 2012.00
IUUC-Xtr-132719 Xenopus tropicalis 70.70 0.00e+00 1391.00
Created Date 25-Jun-2017

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