iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017327.4	ENSCAFT00000027493.4	ENSCAFP00000025568.3
ENSCAFG00000017327.4	ENSCAFT00000047901.1	ENSCAFP00000041278.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-29	101.3	178	215
UBD/Beta-Prp	2.50e-52	178.2	280	539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 178  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 215
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvl 98
           +++l+++++dgti  w+++ +++        + + s    +  +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h+d+v+
   Q: 280  TRYLTSTGADGTICFWQWHVKTMkfrdrpvkFTERSRP--GvqISCSSFSSGGMFITTGSTDHVIRIYylGSEIPEKIAELESHTDKVV 366
           689*************9998777667776433333333..35599***********************7777899************** PP
   S: 99   slsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           +++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W++ tg
   Q: 367  AVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtgnnlpcgEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITG 455
           ******8832468*******************999***************999999********************************* PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           +ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 456  QLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGHLLL 539
           *******9.*********555555..99********************98887755455567788899999*999999999988765 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DCKSTLWNGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTAGGCAAC CGCCGGCCTC CGGTAGACCA GAGGACATTA TGTTGCGTTA GTGCCCCTAG 60
CGGGAAACGA CGAGAACTGC AGGATCTTCT CAGTTTTTAC CTCCCCTCTC TCCACCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	98.56	0.00e+00	3185.00
IUUC-Apl-004016	Anas platyrhynchos	80.50	0.00e+00	2276.00
IUUC-Aca-004722	Anolis carolinensis	78.35	0.00e+00	2217.00
IUUC-Ame-010602	Astyanax mexicanus	76.35	0.00e+00	1144.00
IUUC-Bta-013198	Bos taurus	96.44	0.00e+00	2883.00
IUUC-Cpo-022448	Cavia porcellus	89.11	0.00e+00	2831.00
IUUC-Csa-023166	Chlorocebus sabaeus	96.75	0.00e+00	2976.00
IUUC-Cin-025553	Ciona intestinalis	39.48	5.00e-114	405.00
IUUC-Csv-025813	Ciona savignyi	43.75	0.00e+00	645.00
IUUC-Dre-028508	Danio rerio	66.07	0.00e+00	1892.00
IUUC-Dno-030070	Dasypus novemcinctus	93.79	0.00e+00	3014.00
IUUC-Dor-031052	Dipodomys ordii	87.30	0.00e+00	1358.00
IUUC-Dme-031752	Drosophila melanogaster	50.00	0.00e+00	675.00
IUUC-Ete-032650	Echinops telfairi	86.19	0.00e+00	1843.00
IUUC-Eca-033953	Equus caballus	98.16	0.00e+00	2830.00
IUUC-Eeu-034871	Erinaceus europaeus	83.21	0.00e+00	1353.00
IUUC-Fca-036099	Felis catus	98.06	0.00e+00	3178.00
IUUC-Fal-037246	Ficedula albicollis	82.30	0.00e+00	2449.00
IUUC-Gga-041097	Gallus gallus	82.99	0.00e+00	2538.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.70	0.00e+00	1853.00
IUUC-Hsa-045666	Homo sapiens	96.75	0.00e+00	2976.00
IUUC-Lch-050646	Latimeria chalumnae	60.70	0.00e+00	1832.00
IUUC-Loc-051802	Lepisosteus oculatus	70.16	0.00e+00	2065.00
IUUC-Laf-053942	Loxodonta africana	96.80	0.00e+00	3037.00
IUUC-Mcc-054645	Macaca mulatta	96.87	0.00e+00	2981.00
IUUC-Meu-056321	Macropus eugenii	76.65	0.00e+00	1120.00
IUUC-Mga-060063	Meleagris gallopavo	83.49	0.00e+00	2488.00
IUUC-Mmr-061262	Microcebus murinus	96.87	0.00e+00	3008.00
IUUC-Mdo-062320	Monodelphis domestica	76.45	0.00e+00	2310.00
IUUC-Mmu-063163	Mus musculus	94.83	0.00e+00	3043.00
IUUC-Mpu-066628	Mustela putorius furo	98.06	0.00e+00	3196.00
IUUC-Mlu-068082	Myotis lucifugus	97.47	0.00e+00	2980.00
IUUC-Nle-069609	Nomascus leucogenys	96.81	0.00e+00	2993.00
IUUC-Ont-071589	Oreochromis niloticus	66.51	0.00e+00	1819.00
IUUC-Ocu-074122	Oryctolagus cuniculus	94.99	0.00e+00	2144.00
IUUC-Ola-086580	Oryzias latipes	66.67	0.00e+00	1889.00
IUUC-Oga-089053	Otolemur garnettii	95.89	0.00e+00	3103.00
IUUC-Oar-090042	Ovis aries	97.00	0.00e+00	3165.00
IUUC-Ptr-091268	Pan troglodytes	95.90	0.00e+00	2927.00
IUUC-Pan-092376	Papio anubis	96.87	0.00e+00	2981.00
IUUC-Psi-093408	Pelodiscus sinensis	82.36	0.00e+00	2542.00
IUUC-Pfo-096515	Poecilia formosa	66.48	0.00e+00	1787.00
IUUC-Pab-097672	Pongo abelii	94.76	0.00e+00	2933.00
IUUC-Pva-102512	Pteropus vampyrus	98.33	0.00e+00	2372.00
IUUC-Rno-105797	Rattus norvegicus	94.81	0.00e+00	2934.00
IUUC-Sha-107061	Sarcophilus harrisii	77.34	0.00e+00	2315.00
IUUC-Sit-110017	Setaria italica	29.00	3.00e-56	214.00
IUUC-Sar-113004	Sorex araneus	85.23	0.00e+00	1676.00
IUUC-Tgu-117254	Taeniopygia guttata	83.10	0.00e+00	2444.00
IUUC-Tru-118186	Takifugu rubripes	65.84	0.00e+00	1836.00
IUUC-Tsy-119003	Tarsius syrichta	90.81	0.00e+00	2720.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.98	0.00e+00	1812.00
IUUC-Tbe-127813	Tupaia belangeri	78.03	0.00e+00	931.00
IUUC-Ttr-129265	Tursiops truncatus	93.97	0.00e+00	2862.00
IUUC-Vpa-130736	Vicugna pacos	91.29	0.00e+00	1509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence