iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091268

Ensembl Protein ID

ENSPTRP00000037945.4

UniProt Accession

H2QYU6; H2QYU6_PANTR

Genbank Protein ID

ENSPTRP00000037945

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03131722

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000022060.4	ENSPTRT00000041076.4	ENSPTRP00000037945.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-31	104.5	161	198
UBD/Beta-Prp	1.70e-52	178.4	263	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 161  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 198
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvl 98
           +++l+++++dgti  w+++ +++        + + s    +  +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h+d+v+
   Q: 263  NRYLTSTGADGTICFWQWHVKTMkfrdrpvkFTERSRP--GvqISCSSFSSGGMFITTGSTDHVIRIYylGSEVPEKIAELESHTDKVV 349
           689*************9998777667776433333333..35599***********************877789*************** PP
   S: 99   slsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           +++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W++ tg
   Q: 350  AVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtgnnlpsgEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITG 438
           ******8832468*******************999************998888888889****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           +ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 439  QLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGHLLL 522
           *******9.*********555555..99********************98887755455567788899999***9999999988766 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ IPRVAANAHI PPDYLLKICE 60
RIGPLLDKEI PQSVPGVQTL LGVGRQSLLR DAKDCKSTLW NGSAFAALHR GRPPELPVNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAG CACCTACCCA GATCGAAGCC GGTGGGTAGC TGTGTCGGGG GGTGGGGGGT 60
GCTAAGGGAA TGGGGGCTTA GCGCGAAGGC TGTCAGTTTC TTTTGAAAAA GCTTCTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	96.09	0.00e+00	2967.00
IUUC-Apl-004016	Anas platyrhynchos	79.97	0.00e+00	2261.00
IUUC-Aca-004722	Anolis carolinensis	78.18	0.00e+00	2210.00
IUUC-Ame-010602	Astyanax mexicanus	76.28	0.00e+00	1137.00
IUUC-Bta-013198	Bos taurus	95.73	0.00e+00	2734.00
IUUC-Cfa-020963	Canis familiaris	95.91	0.00e+00	2937.00
IUUC-Cpo-022448	Cavia porcellus	86.25	0.00e+00	2908.00
IUUC-Csa-023166	Chlorocebus sabaeus	98.49	0.00e+00	3011.00
IUUC-Cin-025553	Ciona intestinalis	38.83	8.00e-111	394.00
IUUC-Dre-028508	Danio rerio	65.30	0.00e+00	1850.00
IUUC-Dno-030070	Dasypus novemcinctus	92.33	0.00e+00	2825.00
IUUC-Dor-031052	Dipodomys ordii	79.90	0.00e+00	1437.00
IUUC-Ete-032650	Echinops telfairi	89.96	0.00e+00	1735.00
IUUC-Eca-033953	Equus caballus	97.19	0.00e+00	2683.00
IUUC-Eeu-034871	Erinaceus europaeus	80.91	0.00e+00	1295.00
IUUC-Fca-036099	Felis catus	95.55	0.00e+00	2971.00
IUUC-Fal-037246	Ficedula albicollis	80.89	0.00e+00	2432.00
IUUC-Gga-041097	Gallus gallus	82.22	0.00e+00	2479.00
IUUC-Gac-042435	Gasterosteus aculeatus	64.52	0.00e+00	1809.00
IUUC-Hsa-045666	Homo sapiens	98.61	0.00e+00	3015.00
IUUC-Loc-051802	Lepisosteus oculatus	68.97	0.00e+00	2026.00
IUUC-Laf-053942	Loxodonta africana	95.18	0.00e+00	2964.00
IUUC-Mcc-054645	Macaca mulatta	98.61	0.00e+00	3017.00
IUUC-Meu-056321	Macropus eugenii	76.22	0.00e+00	1088.00
IUUC-Mga-060063	Meleagris gallopavo	83.05	0.00e+00	2470.00
IUUC-Mmr-061262	Microcebus murinus	96.00	0.00e+00	2957.00
IUUC-Mdo-062320	Monodelphis domestica	73.12	0.00e+00	2371.00
IUUC-Mmu-063163	Mus musculus	93.58	0.00e+00	2857.00
IUUC-Mpu-066628	Mustela putorius furo	95.68	0.00e+00	2961.00
IUUC-Mlu-068082	Myotis lucifugus	95.79	0.00e+00	2916.00
IUUC-Nle-069609	Nomascus leucogenys	98.49	0.00e+00	3031.00
IUUC-Ont-071589	Oreochromis niloticus	65.60	0.00e+00	1781.00
IUUC-Ocu-074122	Oryctolagus cuniculus	94.92	0.00e+00	2132.00
IUUC-Ogu-078641	Oryza glumaepatula	24.45	1.00e-28	122.00
IUUC-Ola-086580	Oryzias latipes	65.65	0.00e+00	1846.00
IUUC-Oga-089053	Otolemur garnettii	94.35	0.00e+00	2917.00
IUUC-Oar-090042	Ovis aries	95.50	0.00e+00	2964.00
IUUC-Pan-092376	Papio anubis	98.55	0.00e+00	3016.00
IUUC-Psi-093408	Pelodiscus sinensis	81.26	0.00e+00	2529.00
IUUC-Pfo-096515	Poecilia formosa	64.23	0.00e+00	1749.00
IUUC-Pab-097672	Pongo abelii	96.51	0.00e+00	2972.00
IUUC-Pva-102512	Pteropus vampyrus	96.33	0.00e+00	2303.00
IUUC-Rno-105797	Rattus norvegicus	93.31	0.00e+00	2868.00
IUUC-Sha-107061	Sarcophilus harrisii	76.73	0.00e+00	2309.00
IUUC-Sar-113004	Sorex araneus	83.03	0.00e+00	1518.00
IUUC-Tgu-117254	Taeniopygia guttata	81.88	0.00e+00	2431.00
IUUC-Tru-118186	Takifugu rubripes	65.06	0.00e+00	1805.00
IUUC-Tsy-119003	Tarsius syrichta	89.37	0.00e+00	2677.00
IUUC-Tni-120110	Tetraodon nigroviridis	64.76	0.00e+00	1772.00
IUUC-Tbe-127813	Tupaia belangeri	78.79	0.00e+00	938.00
IUUC-Ttr-129265	Tursiops truncatus	94.88	0.00e+00	2801.00
IUUC-Vpa-130736	Vicugna pacos	90.49	0.00e+00	1499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence