iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021039

Ensembl Protein ID

ENSCAFP00000002195.3

UniProt Accession

E2RIM1; E2RIM1_CANLF

Genbank Protein ID

ENSCAFP00000002195

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007343

Gene Name

NCF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001522.3	ENSCAFT00000002373.3	ENSCAFP00000002195.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-11	44.1	175	228
ULD/UDP/UFD/PB1	2.40e-19	69.6	237	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            ++l+d++++++ eL++k+Gdv+ ++     +++Wl+g  + +g  G+fP+ Fv+ l+
   Q: 175  AEALFDFTGNSKLELNFKAGDVIILL--SRINKDWLEG--TVRGATGIFPQSFVKILK 228
           689**********************9..999*******..8*************9876 PP

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirs......faldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksll..r 78
           t++++++y+++++s      ++++l+++++f+dL++++r+  e++++++al+Y+D+ GDlv+l sDed+  +v++++   s+k l+  +
   Q: 237  TNWLRCYYYEDTISttkdiaVEEELSSTPLFKDLMQLMRR--EFQREDIALNYRDAQGDLVRLLSDEDVGLMVKQAQglpSQKHLFpwK 323
           589**********9**************************..********************************************99* PP
   S: 79   lliqkk 84
           l+i++k
   Q: 324  LHITQK 329
           ***985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MALAQQLRAE SDFEQLPDNI AISANIADIE EKRGFTSYFV FVIEVKTKGG SKYLIYRRYR 60
QFHALQSKLE ERFGPENKSN PFTCSLPTLP AKVYVGVKQE IAEMRIPALN AYMKSLLSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCCAGTGG TGTCCTGGCA CCAAGAAATC CCATCAAGGA AGTCCTCAAA GCCCCTGGGT 60
CAGTGGATTC CTGCAAACCC AGAGTCCAAG GGTGGGCACT TCCCCAACTG CAGTGCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000919--NCF_P40
IPR000270--PB1_dom
IPR001683--Phox
IPR001452--SH3_domain

PROSITE

PS51745--PB1
PS50195--PX
PS50002--SH3

Pfam

PF00564--PB1
PF00787--PX
PF00018--SH3_1

PRINTS

PR00497--P40PHOX
PR00452--SH3DOMAIN

SMART

SM00666--PB1
SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0043020--C:NADPH oxidase complex
GO:0005802--C:trans-Golgi network
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity
GO:0016192--P:vesicle-mediated transport

KEGG

cfa:481277

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001675	Ailuropoda melanoleuca	92.63	0.00e+00	652.00
IUUC-Apl-003431	Anas platyrhynchos	67.85	7.00e-137	479.00
IUUC-Aca-005176	Anolis carolinensis	71.13	1.00e-138	485.00
IUUC-Ame-011492	Astyanax mexicanus	57.75	7.00e-117	413.00
IUUC-Bta-013434	Bos taurus	88.79	4.00e-166	577.00
IUUC-Cja-019788	Callithrix jacchus	87.91	1.00e-180	625.00
IUUC-Cpo-021848	Cavia porcellus	86.14	6.00e-171	593.00
IUUC-Csa-023733	Chlorocebus sabaeus	89.46	4.00e-158	550.00
IUUC-Dre-027732	Danio rerio	53.65	1.00e-100	359.00
IUUC-Dno-029154	Dasypus novemcinctus	77.97	2.00e-152	531.00
IUUC-Eca-034062	Equus caballus	90.56	2.00e-177	614.00
IUUC-Eeu-035129	Erinaceus europaeus	73.65	7.00e-67	247.00
IUUC-Fca-036402	Felis catus	92.63	0.00e+00	657.00
IUUC-Fal-037105	Ficedula albicollis	68.14	4.00e-137	481.00
IUUC-Gmo-039144	Gadus morhua	47.95	1.00e-37	149.00
IUUC-Gga-040526	Gallus gallus	67.85	1.00e-135	476.00
IUUC-Ggo-044667	Gorilla gorilla	90.31	2.00e-138	484.00
IUUC-Hsa-045779	Homo sapiens	89.97	0.00e+00	637.00
IUUC-Itr-048385	Ictidomys tridecemlineatus	70.18	6.00e-130	456.00
IUUC-Lch-050264	Latimeria chalumnae	53.54	2.00e-114	405.00
IUUC-Loc-051887	Lepisosteus oculatus	54.52	6.00e-106	377.00
IUUC-Laf-054411	Loxodonta africana	82.12	2.00e-155	541.00
IUUC-Mcc-055835	Macaca mulatta	89.02	1.00e-176	612.00
IUUC-Meu-056875	Macropus eugenii	80.81	4.00e-92	330.00
IUUC-Mga-059737	Meleagris gallopavo	67.26	2.00e-135	474.00
IUUC-Mmr-061065	Microcebus murinus	88.38	2.00e-126	445.00
IUUC-Mdo-062598	Monodelphis domestica	81.76	4.00e-158	550.00
IUUC-Mmu-063643	Mus musculus	86.14	1.00e-176	611.00
IUUC-Mpu-066142	Mustela putorius furo	93.51	0.00e+00	660.00
IUUC-Mlu-067898	Myotis lucifugus	85.56	2.00e-44	169.00
IUUC-Nle-069935	Nomascus leucogenys	74.57	4.00e-146	510.00
IUUC-Opr-070204	Ochotona princeps	84.23	4.00e-131	460.00
IUUC-Ont-072261	Oreochromis niloticus	56.09	5.00e-108	384.00
IUUC-Oan-072846	Ornithorhynchus anatinus	79.62	5.00e-74	269.00
IUUC-Ocu-074683	Oryctolagus cuniculus	87.06	1.00e-177	615.00
IUUC-Ola-086700	Oryzias latipes	55.01	7.00e-99	353.00
IUUC-Oga-087992	Otolemur garnettii	88.59	4.00e-177	613.00
IUUC-Oar-089828	Ovis aries	87.98	8.00e-164	569.00
IUUC-Pan-092264	Papio anubis	88.50	0.00e+00	627.00
IUUC-Psi-093800	Pelodiscus sinensis	69.03	7.00e-135	473.00
IUUC-Pfo-096677	Poecilia formosa	52.81	2.00e-89	322.00
IUUC-Pab-097920	Pongo abelii	89.38	0.00e+00	634.00
IUUC-Pca-100312	Procavia capensis	73.08	5.00e-100	357.00
IUUC-Pva-102113	Pteropus vampyrus	88.42	2.00e-135	474.00
IUUC-Rno-105777	Rattus norvegicus	86.43	2.00e-176	611.00
IUUC-Sha-106666	Sarcophilus harrisii	80.29	4.00e-163	567.00
IUUC-Ssc-116056	Sus scrofa	87.61	0.00e+00	625.00
IUUC-Tgu-116797	Taeniopygia guttata	68.73	5.00e-139	487.00
IUUC-Tru-117860	Takifugu rubripes	54.76	5.00e-100	357.00
IUUC-Tsy-119537	Tarsius syrichta	90.30	1.00e-85	309.00
IUUC-Tni-119946	Tetraodon nigroviridis	55.68	3.00e-100	358.00
IUUC-Tbe-127274	Tupaia belangeri	73.44	5.00e-105	374.00
IUUC-Ttr-129026	Tursiops truncatus	90.43	2.00e-110	391.00
IUUC-Xtr-131910	Xenopus tropicalis	52.80	2.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence