iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073663

Ensembl Protein ID

ENSOANP00000000271.1

UniProt Accession

F6VD83; F6VD83_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KMT2D

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000141.2	ENSOANT00000000271.1	ENSOANP00000000271.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-21	76.6	839	890

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C+vC++++ + + l++C++C++w+H+ C +l  eee+++  +  + C +C+
   Q: 839  TCPVCRAPYVEGDLLIQCRHCDRWMHASCESLLTEEEVEQAADdgFDCGSCQ 890
           6*********999*******************9899988887788******7 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

GHCWAHHWCA AWSAGVQGQQ GPDLQGVDKA VFSGTSQRCS HCARLGASIP CRSPGCLRLY 60
HFPCAAASGS FQSMKTLQLL CPEHGAEAVP LVSPEDARCV VCDGLGELRD LLFCTSCGHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCATTGCT GGGCTCACCA TTGGTGTGCG GCCTGGTCGG CAGGGGTCCA GGGGCAGCAG 60
GGGCCTGACC TGCAAGGAGT GGACAAGGCC GTCTTCTCGG GGACTTCCCA GGTGGGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00184--RING
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001054	Aegilops tauschii	32.58	4.00e-15	76.30
IUUC-Aml-001806	Ailuropoda melanoleuca	86.08	0.00e+00	906.00
IUUC-Dno-029932	Dasypus novemcinctus	86.27	0.00e+00	907.00
IUUC-Ete-032572	Echinops telfairi	91.11	0.00e+00	804.00
IUUC-Gga-040815	Gallus gallus	82.13	1.00e-130	462.00
IUUC-Mcc-055577	Macaca mulatta	85.29	0.00e+00	833.00
IUUC-Meu-055992	Macropus eugenii	93.15	0.00e+00	909.00
IUUC-Mdo-062876	Monodelphis domestica	77.06	7.00e-163	568.00
IUUC-Mmu-063903	Mus musculus	85.66	0.00e+00	904.00
IUUC-Mpu-066700	Mustela putorius furo	86.27	0.00e+00	906.00
IUUC-Opr-070304	Ochotona princeps	81.44	0.00e+00	734.00
IUUC-Opu-083679	Oryza punctata	31.22	1.00e-24	107.00
IUUC-Osa-085421	Oryza sativa	31.22	1.00e-24	107.00
IUUC-Ptr-091073	Pan troglodytes	86.99	0.00e+00	885.00
IUUC-Pca-100499	Procavia capensis	86.27	0.00e+00	909.00
IUUC-Rno-105660	Rattus norvegicus	86.05	0.00e+00	909.00
IUUC-Sha-107431	Sarcophilus harrisii	92.93	0.00e+00	906.00
IUUC-Sbi-114711	Sorghum bicolor	35.29	3.00e-05	40.40
IUUC-Ssc-115678	Sus scrofa	86.08	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence