iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000090301.2	ENSDART00000170678.1	ENSDARP00000131033.1
ENSDARG00000090301.2	ENSDART00000124110.2	ENSDARP00000108767.1
ENSDARG00000090301.2	ENSDART00000123591.2	ENSDARP00000111894.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-75	255.8	134	461
ULD/UDP/UBQ/UBQ_Other	9.80e-09	35.9	1002	1063

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+Nlg+tCY+N  LQ+ ++  elr++l +  + + + ++++++ +  +++++lq lf+ l++s++++++p+ l+kal+     +++ 
   Q: 134  VGLTNLGATCYVNTFLQVWFHNLELRRALYRfqNSRAEGHNTDSDYEPRTICEHLQYLFALLQNSNRRYIDPSGLVKALG-----LDTG 217
           6******************************553333333333456677******************************9.....7889 PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDaqEf + +l+ le++l                       +++k+   +++i++ F gq++  ++c++c+++s   + f++l+l++
   Q: 218  QQQDAQEFSKLFLSLLEDTL-----------------------SKQKDPNLQNVIQQQFCGQFSYVTVCNKCGRESPLPSRFYELELNI 283
           9*******************.......................456788899************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           +g++     +l++c  +f kee+l+g+n+yyce+c++kq+a++++kl++lP++L ++L+Rf f+++ ++++k+n+ ++fp+ Ld++pf+
   Q: 284  QGHK-----NLTECVTEFLKEEKLDGDNRYYCESCQSKQNATRRIKLQSLPRTLNFQLMRFVFDRQSGHKKKLNTFISFPEVLDMEPFL 367
           ****.....9******************************************************************************* PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......................st 329
           + +ee    k++YeL+av++H G s+ sGHY+a+v++ + + W++f+D+++++++ ++ +   +                       ++
   Q: 368  EGREE----KCTYELSAVLIHRGvSAYSGHYIAHVRDAHTNdWYKFNDEEIEKMEGKKLQLGIEediaetaksqtrkpkcskgyhcsRN 452
           *9554....79**************************77777************9999998655999********************** PP
   S: 330  aYvlfYkrr 338
           aY+l+Yk++
   Q: 453  AYMLVYKQQ 461
           ******986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 13   ltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekk 73
             l v+   t ++LK +i +++++ p +q+L ++G++L +d  tL+++g+ ++s i+l  ++
   Q: 1002 KALIVSANQTLKDLKIQIMHAFSVAPFDQNLSIDGRCLkDDSATLGSLGVIPESIICLKADE 1063
           556689999*****************************9999************99998776 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MHCMIFELLY CVCVLFLVCK ISVNVFRYMC AGLCHLNILW CVLYRMAPRL QLEKAAWRWA 60
EAVRPEDITH EHIELAYRIA VSACKRGACR RNCKGNPNCL VGIGEQSWLG EIDENTFHNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTGAGCGA AGTGTACGTG CTGACGTACT TACGTCAGAC GTCGCGAATA CGTCACGCGT 60
AAGTACGTAC GTCTCATAGA AGTTTGAAAC TGACGAAGGG ACAGAAATAT TTATATAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	34.03	4.00e-81	296.00
IUUC-Aml-001357	Ailuropoda melanoleuca	68.66	0.00e+00	1472.00
IUUC-Atr-002976	Amborella trichopoda	31.79	8.00e-82	298.00
IUUC-Apl-003773	Anas platyrhynchos	68.35	0.00e+00	1329.00
IUUC-Aca-004466	Anolis carolinensis	71.29	0.00e+00	771.00
IUUC-Aly-006249	Arabidopsis lyrata	31.39	7.00e-75	276.00
IUUC-Ath-006700	Arabidopsis thaliana	33.33	5.00e-86	313.00
IUUC-Ame-011554	Astyanax mexicanus	84.22	0.00e+00	1793.00
IUUC-Bta-012573	Bos taurus	69.07	0.00e+00	1491.00
IUUC-Bdi-014149	Brachypodium distachyon	34.03	2.00e-88	320.00
IUUC-Bol-016289	Brassica oleracea	34.13	1.00e-84	308.00
IUUC-Bra-017494	Brassica rapa	33.44	4.00e-88	319.00
IUUC-Cel-018662	Caenorhabditis elegans	30.59	4.00e-29	124.00
IUUC-Cja-019991	Callithrix jacchus	68.39	0.00e+00	1484.00
IUUC-Cfa-020294	Canis familiaris	68.92	0.00e+00	1502.00
IUUC-Cpo-021706	Cavia porcellus	68.35	0.00e+00	1416.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	36.63	2.00e-43	173.00
IUUC-Csa-023931	Chlorocebus sabaeus	69.11	0.00e+00	1498.00
IUUC-Cho-024566	Choloepus hoffmanni	65.72	1.00e-109	391.00
IUUC-Cin-025307	Ciona intestinalis	48.14	2.00e-79	288.00
IUUC-Csv-026006	Ciona savignyi	36.21	5.00e-157	548.00
IUUC-Cne-027065	Cryptococcus neoformans	29.40	1.00e-72	269.00
IUUC-Dno-029633	Dasypus novemcinctus	68.96	0.00e+00	948.00
IUUC-Dor-030809	Dipodomys ordii	54.53	0.00e+00	856.00
IUUC-Ete-032818	Echinops telfairi	71.15	0.00e+00	733.00
IUUC-Eca-033692	Equus caballus	69.20	0.00e+00	1493.00
IUUC-Eeu-035185	Erinaceus europaeus	50.35	5.00e-155	541.00
IUUC-Fca-035676	Felis catus	68.98	0.00e+00	1496.00
IUUC-Fal-036913	Ficedula albicollis	68.39	0.00e+00	1473.00
IUUC-Gmo-038532	Gadus morhua	73.86	0.00e+00	1606.00
IUUC-Gga-041041	Gallus gallus	69.24	0.00e+00	1474.00
IUUC-Gac-042570	Gasterosteus aculeatus	74.75	0.00e+00	1640.00
IUUC-Gma-044136	Glycine max	29.60	6.00e-88	319.00
IUUC-Ggo-045367	Gorilla gorilla	66.35	0.00e+00	1404.00
IUUC-Hsa-046019	Homo sapiens	69.01	0.00e+00	1498.00
IUUC-Hvu-047303	Hordeum vulgare	35.08	2.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	68.07	0.00e+00	1482.00
IUUC-Lch-049989	Latimeria chalumnae	71.17	0.00e+00	1542.00
IUUC-Lpe-051612	Leersia perrieri	31.03	3.00e-80	293.00
IUUC-Loc-052756	Lepisosteus oculatus	77.86	0.00e+00	1723.00
IUUC-Laf-054043	Loxodonta africana	67.85	0.00e+00	1482.00
IUUC-Mcc-054986	Macaca mulatta	67.95	0.00e+00	1482.00
IUUC-Meu-056228	Macropus eugenii	54.59	3.00e-174	605.00
IUUC-Mtr-058610	Medicago truncatula	30.10	3.00e-80	294.00
IUUC-Mga-059896	Meleagris gallopavo	68.37	0.00e+00	1381.00
IUUC-Mvi-060269	Microbotryum violaceum	38.90	3.00e-64	241.00
IUUC-Mmr-060887	Microcebus murinus	69.11	0.00e+00	1492.00
IUUC-Mdo-062506	Monodelphis domestica	69.49	0.00e+00	1498.00
IUUC-Mmu-063642	Mus musculus	67.66	0.00e+00	1483.00
IUUC-Mac-064896	Musa acuminata	32.34	2.00e-79	291.00
IUUC-Mpu-066194	Mustela putorius furo	68.82	0.00e+00	1491.00
IUUC-Mlu-067233	Myotis lucifugus	68.52	0.00e+00	1480.00
IUUC-Nle-069052	Nomascus leucogenys	68.23	0.00e+00	1482.00
IUUC-Opr-070890	Ochotona princeps	71.00	0.00e+00	925.00
IUUC-Ont-071450	Oreochromis niloticus	73.21	0.00e+00	1573.00
IUUC-Oan-073252	Ornithorhynchus anatinus	63.27	0.00e+00	753.00
IUUC-Ocu-073796	Oryctolagus cuniculus	68.47	0.00e+00	1273.00
IUUC-Oba-075563	Oryza barthii	33.28	5.00e-81	296.00
IUUC-Obr-076394	Oryza brachyantha	32.75	3.00e-81	297.00
IUUC-Ogl-077339	Oryza glaberrima	40.00	1.00e-43	170.00
IUUC-Ogu-079007	Oryza glumaepatula	34.21	1.00e-74	275.00
IUUC-Oin-079997	Oryza indica	33.28	4.00e-81	296.00
IUUC-Olo-080364	Oryza longistaminata	33.09	4.00e-84	306.00
IUUC-Ome-081165	Oryza meridionalis	34.21	3.00e-75	277.00
IUUC-Oni-083026	Oryza nivara	33.28	4.00e-81	296.00
IUUC-Opu-083284	Oryza punctata	34.16	4.00e-75	276.00
IUUC-Oru-084797	Oryza rufipogon	33.28	5.00e-81	296.00
IUUC-Osa-086221	Oryza sativa	40.00	1.00e-43	170.00
IUUC-Ola-086568	Oryzias latipes	75.14	0.00e+00	1653.00
IUUC-Oga-088687	Otolemur garnettii	68.54	0.00e+00	1489.00
IUUC-Oar-090345	Ovis aries	68.81	0.00e+00	1415.00
IUUC-Ptr-090734	Pan troglodytes	69.01	0.00e+00	1497.00
IUUC-Pan-091704	Papio anubis	66.60	0.00e+00	1424.00
IUUC-Psi-092937	Pelodiscus sinensis	66.81	0.00e+00	1252.00
IUUC-Ppa-095808	Physcomitrella patens	28.59	7.00e-72	266.00
IUUC-Pab-098129	Pongo abelii	69.01	0.00e+00	1498.00
IUUC-Pop-099494	Populus trichocarpa	31.75	4.00e-77	283.00
IUUC-Pca-100647	Procavia capensis	76.36	1.00e-155	544.00
IUUC-Ppe-102091	Prunus persica	31.46	2.00e-83	304.00
IUUC-Pva-102719	Pteropus vampyrus	68.54	0.00e+00	1478.00
IUUC-Rno-105363	Rattus norvegicus	69.30	0.00e+00	1504.00
IUUC-Sha-107620	Sarcophilus harrisii	66.83	0.00e+00	1379.00
IUUC-Smo-109487	Selaginella moellendorffii	27.42	3.00e-83	303.00
IUUC-Sit-110683	Setaria italica	34.82	7.00e-86	312.00
IUUC-Sly-111377	Solanum lycopersicum	31.13	1.00e-81	298.00
IUUC-Stu-111969	Solanum tuberosum	31.89	4.00e-68	252.00
IUUC-Sar-113099	Sorex araneus	68.60	0.00e+00	1262.00
IUUC-Sbi-113833	Sorghum bicolor	43.67	2.00e-60	226.00
IUUC-Ssc-115279	Sus scrofa	61.09	0.00e+00	926.00
IUUC-Tgu-117519	Taeniopygia guttata	65.31	0.00e+00	1321.00
IUUC-Tru-117651	Takifugu rubripes	73.49	0.00e+00	1632.00
IUUC-Tsy-119201	Tarsius syrichta	66.90	0.00e+00	1324.00
IUUC-Tni-120840	Tetraodon nigroviridis	75.54	0.00e+00	1668.00
IUUC-Tca-121674	Theobroma cacao	28.35	2.00e-86	314.00
IUUC-Tae-125814	Triticum aestivum	34.19	7.00e-82	299.00
IUUC-Tur-126599	Triticum urartu	31.06	2.00e-80	294.00
IUUC-Tbe-127782	Tupaia belangeri	61.53	0.00e+00	1265.00
IUUC-Ttr-128312	Tursiops truncatus	67.78	0.00e+00	1461.00
IUUC-Vpa-130348	Vicugna pacos	68.62	0.00e+00	1413.00
IUUC-Vvi-131353	Vitis vinifera	31.64	6.00e-81	296.00
IUUC-Xtr-132172	Xenopus tropicalis	62.08	0.00e+00	1203.00
IUUC-Xma-133263	Xiphophorus maculatus	75.69	0.00e+00	1611.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence