iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036913

Ensembl Protein ID

ENSFALP00000003882.1

UniProt Accession

U3JM78; U3JM78_FICAL

Genbank Protein ID

ENSFALP00000003882

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01022000

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000003726.1	ENSFALT00000003898.1	ENSFALP00000003882.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-73	248.0	89	414
ULD/UDP/UBQ/UBQ_Other	1.80e-11	43.4	944	1003

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp...kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+N  LQ+ +   elr++l    ++++ +  p   + + ++++++lq lf+ l++sk+++++p+ ++kal+     +++
   Q: 89   VGLTNLGATCYVNTFLQMWFLNLELRQALYL-CPSACGDGIPkdtDYEPQTICEHLQYLFALLQNSKRRYIDPSGFVKALG-----LDT 171
           6*****************************9.777777765522255667******************************9.....788 PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
            +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f++l+l+
   Q: 172  GQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLVSKFYELELN 237
           99*******************.......................457889999************************************ PP
   S: 176  vpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           ++g++     +l+dc+ +f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + Ld++pf
   Q: 238  IQGHK-----QLTDCITEFLKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELLDMEPF 321
           *****.....9**********************************************************************99****** PP
   S: 265  ctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......................s 328
           +++++      + YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +                       +
   Q: 322  MEQKNG----VYVYELSAVLIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqsrkpkcgkgahcsR 406
           ***553....79**************************55555************9999998665999********************* PP
   S: 329  taYvlfYk 336
           +aY+l+Y+
   Q: 407  NAYMLVYR 414
           *******8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
            v+ s t +eLK +i +++++ p +q+L ++GkiL +d  tL+++g+ ++s+i+l  +++
   Q: 944  LVSASQTLKELKIQIMHAFSVAPFDQNLSLDGKILsDDTATLGSLGVIPESVILLKADEP 1003
           48999*************************************************988775 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWTETVPP EAVAQEHIEA AYRVRLEPCQ RGACRRNCRG NPNCLVGIGE 60
HVWLGEIDEN SFHNIDDPNC ERRKKNAFVG LTNLGATCYV NTFLQMWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGTGGAGG AAGCCCCGCC CCTAGCTCCG CGCGTCGCGG CCCGGCAACG TCAGCGCCTC 60
CACGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGCGTCGC GGCCCGGCAA CGTCAGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101820440

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	29.54	5.00e-81	295.00
IUUC-Aml-001357	Ailuropoda melanoleuca	86.71	0.00e+00	1821.00
IUUC-Atr-002976	Amborella trichopoda	31.73	4.00e-78	286.00
IUUC-Apl-003773	Anas platyrhynchos	95.39	0.00e+00	1820.00
IUUC-Aca-004466	Anolis carolinensis	84.69	0.00e+00	910.00
IUUC-Aly-006249	Arabidopsis lyrata	30.48	5.00e-73	269.00
IUUC-Ath-006700	Arabidopsis thaliana	31.58	3.00e-80	293.00
IUUC-Ame-011554	Astyanax mexicanus	67.33	0.00e+00	1433.00
IUUC-Bta-012573	Bos taurus	86.72	0.00e+00	1828.00
IUUC-Bdi-014149	Brachypodium distachyon	32.32	2.00e-81	297.00
IUUC-Bol-016289	Brassica oleracea	29.60	5.00e-81	295.00
IUUC-Bra-017494	Brassica rapa	32.80	9.00e-84	305.00
IUUC-Cel-018662	Caenorhabditis elegans	28.53	8.00e-31	129.00
IUUC-Cja-019991	Callithrix jacchus	85.63	0.00e+00	1819.00
IUUC-Cfa-020294	Canis familiaris	86.69	0.00e+00	1849.00
IUUC-Cpo-021706	Cavia porcellus	84.89	0.00e+00	1732.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	32.29	1.00e-43	173.00
IUUC-Csa-023931	Chlorocebus sabaeus	86.50	0.00e+00	1831.00
IUUC-Cho-024566	Choloepus hoffmanni	86.28	5.00e-138	485.00
IUUC-Cin-025307	Ciona intestinalis	48.14	6.00e-77	280.00
IUUC-Csv-026006	Ciona savignyi	36.60	3.00e-152	532.00
IUUC-Cne-027065	Cryptococcus neoformans	27.50	2.00e-67	251.00
IUUC-Dre-027624	Danio rerio	68.58	0.00e+00	1476.00
IUUC-Dno-029633	Dasypus novemcinctus	87.56	0.00e+00	1183.00
IUUC-Dor-030809	Dipodomys ordii	66.83	0.00e+00	1064.00
IUUC-Ete-032818	Echinops telfairi	83.20	0.00e+00	862.00
IUUC-Eca-033692	Equus caballus	87.08	0.00e+00	1838.00
IUUC-Eeu-035185	Erinaceus europaeus	66.49	0.00e+00	697.00
IUUC-Fca-035676	Felis catus	86.29	0.00e+00	1842.00
IUUC-Gmo-038532	Gadus morhua	64.72	0.00e+00	1389.00
IUUC-Gga-041041	Gallus gallus	95.74	0.00e+00	1991.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.89	0.00e+00	1424.00
IUUC-Gma-044136	Glycine max	29.67	1.00e-90	327.00
IUUC-Ggo-045367	Gorilla gorilla	82.50	0.00e+00	1712.00
IUUC-Hsa-046019	Homo sapiens	86.79	0.00e+00	1836.00
IUUC-Hvu-047303	Hordeum vulgare	34.28	3.00e-65	242.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	84.38	0.00e+00	1810.00
IUUC-Lch-049989	Latimeria chalumnae	76.03	0.00e+00	1631.00
IUUC-Lpe-051612	Leersia perrieri	32.81	2.00e-79	290.00
IUUC-Loc-052756	Lepisosteus oculatus	70.36	0.00e+00	1538.00
IUUC-Laf-054043	Loxodonta africana	85.88	0.00e+00	1830.00
IUUC-Mcc-054986	Macaca mulatta	85.17	0.00e+00	1813.00
IUUC-Meu-056228	Macropus eugenii	71.16	0.00e+00	785.00
IUUC-Mtr-058610	Medicago truncatula	30.62	2.00e-82	300.00
IUUC-Mga-059896	Meleagris gallopavo	94.49	0.00e+00	1872.00
IUUC-Mvi-060269	Microbotryum violaceum	37.28	4.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	86.60	0.00e+00	1832.00
IUUC-Mdo-062506	Monodelphis domestica	87.27	0.00e+00	1848.00
IUUC-Mmu-063642	Mus musculus	83.70	0.00e+00	1791.00
IUUC-Mac-064896	Musa acuminata	32.20	2.00e-78	287.00
IUUC-Mpu-066194	Mustela putorius furo	86.89	0.00e+00	1831.00
IUUC-Mlu-067233	Myotis lucifugus	86.33	0.00e+00	1829.00
IUUC-Nle-069052	Nomascus leucogenys	85.51	0.00e+00	1817.00
IUUC-Opr-070890	Ochotona princeps	85.71	0.00e+00	1121.00
IUUC-Ont-071450	Oreochromis niloticus	64.52	0.00e+00	1378.00
IUUC-Oan-073252	Ornithorhynchus anatinus	85.15	0.00e+00	989.00
IUUC-Ocu-073796	Oryctolagus cuniculus	86.45	0.00e+00	1582.00
IUUC-Oba-075563	Oryza barthii	34.18	2.00e-80	294.00
IUUC-Obr-076394	Oryza brachyantha	32.01	2.00e-79	290.00
IUUC-Ogl-077339	Oryza glaberrima	39.10	2.00e-40	159.00
IUUC-Ogu-079007	Oryza glumaepatula	35.04	2.00e-75	277.00
IUUC-Oin-079997	Oryza indica	34.80	1.00e-80	295.00
IUUC-Olo-080364	Oryza longistaminata	34.80	1.00e-80	295.00
IUUC-Ome-081165	Oryza meridionalis	33.87	2.00e-75	277.00
IUUC-Oni-083026	Oryza nivara	34.80	1.00e-80	295.00
IUUC-Opu-083284	Oryza punctata	35.19	3.00e-75	276.00
IUUC-Oru-084797	Oryza rufipogon	34.18	1.00e-80	294.00
IUUC-Osa-086221	Oryza sativa	39.10	2.00e-40	159.00
IUUC-Ola-086568	Oryzias latipes	66.57	0.00e+00	1436.00
IUUC-Oga-088687	Otolemur garnettii	85.43	0.00e+00	1817.00
IUUC-Oar-090345	Ovis aries	87.14	0.00e+00	1751.00
IUUC-Ptr-090734	Pan troglodytes	86.69	0.00e+00	1834.00
IUUC-Pan-091704	Papio anubis	83.48	0.00e+00	1746.00
IUUC-Psi-092937	Pelodiscus sinensis	91.69	0.00e+00	1689.00
IUUC-Ppa-095808	Physcomitrella patens	28.12	2.00e-70	261.00
IUUC-Pab-098129	Pongo abelii	86.69	0.00e+00	1833.00
IUUC-Pop-099494	Populus trichocarpa	31.89	9.00e-79	288.00
IUUC-Pca-100647	Procavia capensis	89.70	0.00e+00	633.00
IUUC-Ppe-102091	Prunus persica	29.37	2.00e-82	300.00
IUUC-Pva-102719	Pteropus vampyrus	86.50	0.00e+00	1823.00
IUUC-Rno-105363	Rattus norvegicus	85.05	0.00e+00	1811.00
IUUC-Sha-107620	Sarcophilus harrisii	84.84	0.00e+00	1730.00
IUUC-Smo-109487	Selaginella moellendorffii	27.52	1.00e-81	298.00
IUUC-Sit-110683	Setaria italica	29.76	1.00e-80	294.00
IUUC-Sly-111377	Solanum lycopersicum	31.09	1.00e-77	284.00
IUUC-Stu-111969	Solanum tuberosum	31.27	1.00e-68	254.00
IUUC-Sar-113099	Sorex araneus	86.87	0.00e+00	1578.00
IUUC-Sbi-113833	Sorghum bicolor	42.86	1.00e-56	212.00
IUUC-Ssc-115279	Sus scrofa	79.37	0.00e+00	1183.00
IUUC-Tgu-117519	Taeniopygia guttata	94.56	0.00e+00	1861.00
IUUC-Tru-117651	Takifugu rubripes	66.42	0.00e+00	1419.00
IUUC-Tsy-119201	Tarsius syrichta	84.16	0.00e+00	1644.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.76	0.00e+00	1446.00
IUUC-Tca-121674	Theobroma cacao	31.16	1.00e-85	311.00
IUUC-Tae-125247	Triticum aestivum	28.67	6.00e-82	299.00
IUUC-Tur-126599	Triticum urartu	30.05	8.00e-81	295.00
IUUC-Tbe-127782	Tupaia belangeri	76.60	0.00e+00	1549.00
IUUC-Ttr-128312	Tursiops truncatus	85.54	0.00e+00	1800.00
IUUC-Vpa-130348	Vicugna pacos	86.90	0.00e+00	1751.00
IUUC-Vvi-131353	Vitis vinifera	32.25	6.00e-83	302.00
IUUC-Xtr-132172	Xenopus tropicalis	70.11	0.00e+00	1319.00
IUUC-Xma-133263	Xiphophorus maculatus	67.21	0.00e+00	1407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence