iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013250

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02035345

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004147.5	ENSBTAT00000005426.5	ENSBTAP00000005426.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	88.81	0.00e+00	1891.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.95	3.00e-42	168.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MRRFKRKHLT AIECQHLARS HLAASQSFQR WTSRDPNHGL YPRPRTKRGA RGQGCLRYSL 60
DFFLAGQQPC TNDMAKSNSV GQDSSKDSED EMIFVAGSPC ALPPGGDGEA RLHSSGSALP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAGGGCTC CCACTGCCCC TGGGAAGCCG CGACCCGGAG CCCGGGTGGC CCGGGACCTG 60
AGGCGGCGGC GGCGGGAGCC CCGATGCGGA TCGCCATAGT GAGTGAGGCC GCCGGCGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	47.83	1.00e-04	42.70
IUUC-Aml-001396	Ailuropoda melanoleuca	90.82	0.00e+00	1913.00
IUUC-Atr-002826	Amborella trichopoda	40.00	6.00e-04	40.40
IUUC-Apl-003317	Anas platyrhynchos	48.46	0.00e+00	927.00
IUUC-Aca-004498	Anolis carolinensis	53.85	0.00e+00	950.00
IUUC-Ath-007293	Arabidopsis thaliana	37.68	4.00e-03	37.70
IUUC-Ani-009226	Aspergillus nidulans	27.06	1.00e-05	45.80
IUUC-Ate-010526	Aspergillus terreus	29.82	8.00e-04	39.70
IUUC-Ame-011808	Astyanax mexicanus	57.64	2.00e-133	468.00
IUUC-Bol-015348	Brassica oleracea	37.68	3.00e-03	38.10
IUUC-Cja-019638	Callithrix jacchus	89.10	0.00e+00	1915.00
IUUC-Cfa-020195	Canis familiaris	91.15	0.00e+00	1826.00
IUUC-Cpo-022269	Cavia porcellus	84.13	0.00e+00	1753.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	3.00e-08	54.30
IUUC-Csa-024060	Chlorocebus sabaeus	90.23	0.00e+00	1723.00
IUUC-Cho-025003	Choloepus hoffmanni	87.88	0.00e+00	700.00
IUUC-Cin-025694	Ciona intestinalis	27.76	1.00e-29	124.00
IUUC-Dre-028083	Danio rerio	49.55	0.00e+00	852.00
IUUC-Dno-029203	Dasypus novemcinctus	85.00	0.00e+00	1714.00
IUUC-Dor-030477	Dipodomys ordii	95.91	0.00e+00	785.00
IUUC-Ete-032861	Echinops telfairi	85.66	0.00e+00	1801.00
IUUC-Eca-033205	Equus caballus	90.82	0.00e+00	1957.00
IUUC-Eeu-034784	Erinaceus europaeus	86.22	0.00e+00	1193.00
IUUC-Fca-035797	Felis catus	90.55	0.00e+00	1921.00
IUUC-Gmo-038855	Gadus morhua	46.28	3.00e-121	429.00
IUUC-Gga-040326	Gallus gallus	50.05	0.00e+00	962.00
IUUC-Gac-042240	Gasterosteus aculeatus	46.26	0.00e+00	728.00
IUUC-Ggo-045050	Gorilla gorilla	85.57	0.00e+00	1761.00
IUUC-Hsa-046650	Homo sapiens	88.81	0.00e+00	1852.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	94.06	0.00e+00	762.00
IUUC-Lch-050231	Latimeria chalumnae	48.87	5.00e-155	541.00
IUUC-Loc-051884	Lepisosteus oculatus	49.53	0.00e+00	969.00
IUUC-Lma-053267	Leptosphaeria maculans	22.22	1.00e-03	38.90
IUUC-Laf-053843	Loxodonta africana	87.67	0.00e+00	1858.00
IUUC-Mcc-055570	Macaca mulatta	89.39	0.00e+00	1885.00
IUUC-Meu-056798	Macropus eugenii	66.67	3.00e-150	526.00
IUUC-Mtr-057915	Medicago truncatula	36.76	5.00e-04	40.80
IUUC-Mga-059648	Meleagris gallopavo	50.98	0.00e+00	917.00
IUUC-Mmr-060757	Microcebus murinus	87.02	0.00e+00	1799.00
IUUC-Mdo-061913	Monodelphis domestica	68.72	0.00e+00	1359.00
IUUC-Mmu-064337	Mus musculus	86.90	0.00e+00	1865.00
IUUC-Mpu-066483	Mustela putorius furo	88.91	0.00e+00	1910.00
IUUC-Mlu-068204	Myotis lucifugus	84.08	0.00e+00	1781.00
IUUC-Ncr-068735	Neurospora crassa	24.40	1.00e-03	39.30
IUUC-Nle-070053	Nomascus leucogenys	89.20	0.00e+00	1830.00
IUUC-Opr-070588	Ochotona princeps	83.56	0.00e+00	1743.00
IUUC-Ont-072655	Oreochromis niloticus	46.70	0.00e+00	755.00
IUUC-Oan-073351	Ornithorhynchus anatinus	61.90	0.00e+00	1276.00
IUUC-Ocu-074465	Oryctolagus cuniculus	87.40	0.00e+00	1794.00
IUUC-Oin-079176	Oryza indica	24.24	2.00e-05	43.50
IUUC-Opu-083155	Oryza punctata	47.50	2.00e-03	38.10
IUUC-Olu-087831	Ostreococcus lucimarinus	31.49	5.00e-63	237.00
IUUC-Oga-089088	Otolemur garnettii	86.81	0.00e+00	1794.00
IUUC-Oar-089870	Ovis aries	96.85	0.00e+00	2031.00
IUUC-Ptr-090957	Pan troglodytes	88.99	0.00e+00	1830.00
IUUC-Pan-092632	Papio anubis	89.10	0.00e+00	1833.00
IUUC-Psi-093035	Pelodiscus sinensis	54.72	0.00e+00	1103.00
IUUC-Pno-094870	Phaeosphaeria nodorum	25.27	4.00e-05	43.90
IUUC-Ppa-095660	Physcomitrella patens	38.46	6.00e-04	40.40
IUUC-Pfo-096902	Poecilia formosa	44.52	0.00e+00	685.00
IUUC-Pab-098206	Pongo abelii	88.99	0.00e+00	1728.00
IUUC-Pop-098801	Populus trichocarpa	34.72	6.00e-04	40.40
IUUC-Pca-100238	Procavia capensis	82.12	0.00e+00	1724.00
IUUC-Ppe-101748	Prunus persica	35.94	7.00e-03	37.00
IUUC-Pva-103182	Pteropus vampyrus	88.53	0.00e+00	1837.00
IUUC-Pte-104033	Pyrenophora teres	24.29	2.00e-04	41.60
IUUC-Pyt-104599	Pyrenophora triticirepentis	24.29	2.00e-04	42.00
IUUC-Rno-105141	Rattus norvegicus	87.19	0.00e+00	1870.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	2.00e-03	37.70
IUUC-Sha-106827	Sarcophilus harrisii	67.21	0.00e+00	1422.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.31	1.00e-41	165.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.86	6.00e-42	166.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	25.00	1.00e-03	38.50
IUUC-Sly-111170	Solanum lycopersicum	33.33	5.60e-02	32.70
IUUC-Sre-115025	Sporisorium reilianum	33.65	9.00e-40	159.00
IUUC-Ssc-116188	Sus scrofa	95.38	0.00e+00	1276.00
IUUC-Tgu-116612	Taeniopygia guttata	58.09	1.00e-158	552.00
IUUC-Tsy-119560	Tarsius syrichta	81.45	1.00e-114	408.00
IUUC-Tni-120734	Tetraodon nigroviridis	46.36	0.00e+00	721.00
IUUC-Tca-121338	Theobroma cacao	30.36	1.00e-02	36.20
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tme-127009	Tuber melanosporum	30.77	3.00e-03	37.70
IUUC-Tbe-127431	Tupaia belangeri	87.14	0.00e+00	1570.00
IUUC-Ttr-128744	Tursiops truncatus	89.21	0.00e+00	1854.00
IUUC-Uma-129536	Ustilago maydis	34.69	3.00e-42	167.00
IUUC-Vpa-130123	Vicugna pacos	77.47	6.00e-102	365.00
IUUC-Vvi-131025	Vitis vinifera	37.50	3.00e-03	38.10
IUUC-Xtr-132902	Xenopus tropicalis	59.07	0.00e+00	1013.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence