iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053646

UUCD1 version

UUC-LoA-00350

Ensembl Protein ID

ENSLAFP00000008619.3

UniProt Accession

G3T5B5; G3T5B5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE4B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010285.3	ENSLAFT00000027809.1	ENSLAFP00000024827.1
ENSLAFG00000010285.3	ENSLAFT00000010291.3	ENSLAFP00000008619.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.00e-22	78.1	1236	1307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
            p+ef++p++ +lM+dPv lpsG  +drs I ++l ++ + +P++rq+lte++l P  +l++ i+aw++e+++
   Q: 1236 APDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPT-DPFNRQTLTESMLEPVPELKEQIHAWMKEKQN 1307
           79**********************************9998.****************************9986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS QSLGLNVHSM 60
TPATSPIGAS GVAHRSQSSE GVSSLSSSPS NSLETQSQSL SRSQSMDIDG VSCEKSMSQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGC TGAGCGCTGA TGAGGTGAGG AGGTTGGGGG GACACCTTGG GGGACTAGTT 60
GGCAACTCTT TGGCGCTTTG GACAAAGATG ATATTGCGCC AGTGGAGCTT GGCCTTTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008626--P:granzyme-mediated apoptotic signaling pathway
GO:0031175--P:neuron projection development
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0034976--P:response to endoplasmic reticulum stress
GO:0009411--P:response to UV
GO:0003222--P:ventricular trabecula myocardium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000585	Aegilops tauschii	32.81	3.00e-94	339.00
IUUC-Aml-002396	Ailuropoda melanoleuca	98.99	0.00e+00	1741.00
IUUC-Atr-002479	Amborella trichopoda	31.66	4.00e-98	352.00
IUUC-Apl-003747	Anas platyrhynchos	93.71	0.00e+00	1675.00
IUUC-Aca-004866	Anolis carolinensis	93.60	0.00e+00	1660.00
IUUC-Aly-006300	Arabidopsis lyrata	30.76	2.00e-89	323.00
IUUC-Ath-006962	Arabidopsis thaliana	30.62	2.00e-86	313.00
IUUC-Ago-007880	Ashbya gossypii	29.43	2.00e-76	280.00
IUUC-Acl-008289	Aspergillus clavatus	30.52	1.00e-98	355.00
IUUC-Afl-008711	Aspergillus flavus	30.49	2.00e-103	370.00
IUUC-Afu-008766	Aspergillus fumigatus	30.87	2.00e-103	370.00
IUUC-Ani-009126	Aspergillus nidulans	30.33	6.00e-100	358.00
IUUC-Ang-009837	Aspergillus niger	30.44	6.00e-99	355.00
IUUC-Aor-009919	Aspergillus oryzae	30.06	2.00e-99	357.00
IUUC-Ate-010300	Aspergillus terreus	31.29	2.00e-105	377.00
IUUC-Ame-011355	Astyanax mexicanus	85.06	0.00e+00	1575.00
IUUC-Bgr-011995	Blumeria graminis	30.22	3.00e-100	360.00
IUUC-Bta-013056	Bos taurus	99.22	0.00e+00	1745.00
IUUC-Bci-013605	Botrytis cinerea	28.72	3.00e-88	320.00
IUUC-Bdi-015032	Brachypodium distachyon	29.87	4.00e-89	323.00
IUUC-Bol-016124	Brassica oleracea	30.75	2.00e-95	343.00
IUUC-Bra-017426	Brassica rapa	30.48	1.00e-95	344.00
IUUC-Cel-018606	Caenorhabditis elegans	30.89	2.00e-98	353.00
IUUC-Cja-018872	Callithrix jacchus	95.11	0.00e+00	2243.00
IUUC-Cfa-020045	Canis familiaris	98.88	0.00e+00	1738.00
IUUC-Cpo-022309	Cavia porcellus	97.88	0.00e+00	1722.00
IUUC-Cre-022726	Chlamydomonas reinhardtii	29.42	9.00e-50	191.00
IUUC-Csa-024003	Chlorocebus sabaeus	97.56	0.00e+00	1102.00
IUUC-Cho-025092	Choloepus hoffmanni	91.50	0.00e+00	1061.00
IUUC-Cin-025533	Ciona intestinalis	47.85	0.00e+00	832.00
IUUC-Csv-026081	Ciona savignyi	64.52	9.00e-61	225.00
IUUC-Cgl-026710	Colletotrichum gloeosporioides	31.17	5.00e-105	375.00
IUUC-Cne-027098	Cryptococcus neoformans	30.59	3.00e-104	373.00
IUUC-Cme-027352	Cyanidioschyzon merolae	32.64	1.00e-86	315.00
IUUC-Dre-027979	Danio rerio	84.36	0.00e+00	1514.00
IUUC-Dno-029282	Dasypus novemcinctus	98.88	0.00e+00	1739.00
IUUC-Dor-030904	Dipodomys ordii	79.09	0.00e+00	1071.00
IUUC-Dse-031393	Dothistroma septosporum	29.20	3.00e-96	347.00
IUUC-Dme-031666	Drosophila melanogaster	42.22	0.00e+00	688.00
IUUC-Ete-032519	Echinops telfairi	87.61	0.00e+00	737.00
IUUC-Eca-033778	Equus caballus	98.77	0.00e+00	1731.00
IUUC-Eeu-035315	Erinaceus europaeus	82.22	0.00e+00	1201.00
IUUC-Fca-035658	Felis catus	98.55	0.00e+00	1731.00
IUUC-Fal-037638	Ficedula albicollis	83.78	0.00e+00	1996.00
IUUC-Fox-037909	Fusarium oxysporum	29.06	4.00e-94	339.00
IUUC-Fso-038406	Fusarium solani	29.70	3.00e-95	343.00
IUUC-Gmo-039379	Gadus morhua	84.10	0.00e+00	1511.00
IUUC-Ggr-039851	Gaeumannomyces graminis	31.87	1.00e-104	374.00
IUUC-Gga-041136	Gallus gallus	93.81	0.00e+00	1677.00
IUUC-Gac-041910	Gasterosteus aculeatus	84.51	0.00e+00	1525.00
IUUC-Gma-043995	Glycine max	30.20	5.00e-92	332.00
IUUC-Ggo-045354	Gorilla gorilla	92.43	0.00e+00	1592.00
IUUC-Hsa-046880	Homo sapiens	98.67	0.00e+00	1781.00
IUUC-Hvu-047157	Hordeum vulgare	33.12	7.00e-90	325.00
IUUC-Itr-048213	Ictidomys tridecemlineatus	98.20	0.00e+00	640.00
IUUC-Kpa-049211	Komagataella pastoris	27.80	1.00e-74	274.00
IUUC-Lch-050534	Latimeria chalumnae	79.01	0.00e+00	1901.00
IUUC-Lpe-051022	Leersia perrieri	30.66	3.00e-90	326.00
IUUC-Loc-052622	Lepisosteus oculatus	86.23	0.00e+00	1541.00
IUUC-Lma-053241	Leptosphaeria maculans	29.84	1.00e-95	344.00
IUUC-Mcc-055588	Macaca mulatta	98.88	0.00e+00	1741.00
IUUC-Meu-055999	Macropus eugenii	73.25	0.00e+00	1627.00
IUUC-Mor-057064	Magnaporthe oryzae	31.13	2.00e-104	374.00
IUUC-Mpo-057452	Magnaporthe poae	31.98	3.00e-106	380.00
IUUC-Mtr-058016	Medicago truncatula	29.78	6.00e-98	352.00
IUUC-Mla-058887	Melampsora laricipopulina	32.93	2.00e-108	386.00
IUUC-Mga-059497	Meleagris gallopavo	93.58	0.00e+00	1671.00
IUUC-Mvi-060343	Microbotryum violaceum	33.99	1.00e-110	394.00
IUUC-Mmr-061173	Microcebus murinus	87.88	0.00e+00	1857.00
IUUC-Mdo-062102	Monodelphis domestica	95.61	0.00e+00	1683.00
IUUC-Mmu-063223	Mus musculus	92.20	0.00e+00	1721.00
IUUC-Mac-065531	Musa acuminata	30.90	3.00e-95	343.00
IUUC-Mpu-066624	Mustela putorius furo	66.78	0.00e+00	1053.00
IUUC-Mlu-068018	Myotis lucifugus	98.21	0.00e+00	1725.00
IUUC-Nfi-068590	Neosartorya fischeri	31.30	2.00e-104	374.00
IUUC-Ncr-068901	Neurospora crassa	31.40	8.00e-102	365.00
IUUC-Nle-069605	Nomascus leucogenys	97.56	0.00e+00	1725.00
IUUC-Opr-071011	Ochotona princeps	83.91	0.00e+00	849.00
IUUC-Ont-072304	Oreochromis niloticus	83.79	0.00e+00	1500.00
IUUC-Oan-073410	Ornithorhynchus anatinus	97.38	0.00e+00	1093.00
IUUC-Ocu-074910	Oryctolagus cuniculus	93.22	0.00e+00	2106.00
IUUC-Oba-075073	Oryza barthii	30.51	3.00e-96	346.00
IUUC-Obr-076452	Oryza brachyantha	30.79	1.00e-94	341.00
IUUC-Ogl-077141	Oryza glaberrima	30.51	2.00e-96	347.00
IUUC-Ogu-078116	Oryza glumaepatula	30.51	2.00e-96	347.00
IUUC-Oin-079066	Oryza indica	30.63	1.00e-96	347.00
IUUC-Olo-080253	Oryza longistaminata	28.83	2.00e-82	300.00
IUUC-Ome-081263	Oryza meridionalis	30.39	9.00e-96	345.00
IUUC-Oni-082019	Oryza nivara	30.63	1.00e-96	348.00
IUUC-Opu-083558	Oryza punctata	30.55	4.00e-97	349.00
IUUC-Oru-085002	Oryza rufipogon	30.51	4.00e-96	346.00
IUUC-Osa-085980	Oryza sativa	30.63	1.00e-96	347.00
IUUC-Ola-086323	Oryzias latipes	74.90	0.00e+00	1453.00
IUUC-Olu-087901	Ostreococcus lucimarinus	31.06	5.00e-97	348.00
IUUC-Oga-087969	Otolemur garnettii	94.30	0.00e+00	1632.00
IUUC-Oar-090020	Ovis aries	88.88	0.00e+00	2039.00
IUUC-Ptr-091589	Pan troglodytes	98.67	0.00e+00	1782.00
IUUC-Pan-091718	Papio anubis	99.09	0.00e+00	864.00
IUUC-Psi-093013	Pelodiscus sinensis	85.42	0.00e+00	2075.00
IUUC-Pma-094627	Petromyzon marinus	74.10	0.00e+00	626.00
IUUC-Pno-094840	Phaeosphaeria nodorum	29.82	1.00e-102	368.00
IUUC-Ppa-095989	Physcomitrella patens	29.48	2.00e-97	350.00
IUUC-Pfo-096436	Poecilia formosa	84.71	0.00e+00	1552.00
IUUC-Pab-098275	Pongo abelii	84.19	0.00e+00	1422.00
IUUC-Pop-098797	Populus trichocarpa	29.98	4.00e-99	356.00
IUUC-Pca-100478	Procavia capensis	81.52	0.00e+00	949.00
IUUC-Ppe-101230	Prunus persica	30.65	1.00e-100	361.00
IUUC-Pva-102459	Pteropus vampyrus	93.96	0.00e+00	1626.00
IUUC-Pgr-103485	Puccinia graminis	32.81	3.00e-108	386.00
IUUC-Ptt-104001	Puccinia triticina	42.74	1.00e-45	178.00
IUUC-Pte-104084	Pyrenophora teres	32.13	5.00e-110	392.00
IUUC-Pyt-104484	Pyrenophora triticirepentis	31.85	2.00e-109	390.00
IUUC-Rno-105719	Rattus norvegicus	92.20	0.00e+00	1722.00
IUUC-Sce-106135	Saccharomyces cerevisiae	36.87	1.00e-72	267.00
IUUC-Sha-106760	Sarcophilus harrisii	95.27	0.00e+00	1676.00
IUUC-Sja-107698	Schizosaccharomyces japonicus	32.59	3.00e-113	403.00
IUUC-Spo-108076	Schizosaccharomyces pombe	33.21	2.00e-107	384.00
IUUC-Ssl-108624	Sclerotinia sclerotiorum	29.41	1.00e-99	357.00
IUUC-Smo-108769	Selaginella moellendorffii	29.76	4.00e-88	319.00
IUUC-Sit-109949	Setaria italica	30.98	5.00e-92	332.00
IUUC-Sly-110973	Solanum lycopersicum	31.22	7.00e-85	308.00
IUUC-Stu-112372	Solanum tuberosum	29.95	2.00e-100	360.00
IUUC-Sar-113469	Sorex araneus	89.95	0.00e+00	1018.00
IUUC-Sbi-113828	Sorghum bicolor	30.41	3.00e-95	343.00
IUUC-Sre-114967	Sporisorium reilianum	32.64	2.00e-101	364.00
IUUC-Ssc-115655	Sus scrofa	98.27	0.00e+00	1113.00
IUUC-Tgu-117290	Taeniopygia guttata	84.96	0.00e+00	1974.00
IUUC-Tru-118193	Takifugu rubripes	75.99	0.00e+00	1781.00
IUUC-Tsy-118926	Tarsius syrichta	92.67	0.00e+00	2158.00
IUUC-Tni-120862	Tetraodon nigroviridis	85.12	0.00e+00	1504.00
IUUC-Tca-121096	Theobroma cacao	31.40	3.00e-100	359.00
IUUC-Tre-122104	Trichoderma reesei	30.58	5.00e-98	353.00
IUUC-Tvi-122345	Trichoderma virens	30.65	5.00e-102	366.00
IUUC-Tae-124607	Triticum aestivum	31.85	7.00e-95	342.00
IUUC-Tur-126056	Triticum urartu	32.45	2.00e-94	340.00
IUUC-Tme-127074	Tuber melanosporum	32.77	1.00e-98	354.00
IUUC-Tbe-127533	Tupaia belangeri	91.13	0.00e+00	1869.00
IUUC-Ttr-128757	Tursiops truncatus	92.38	0.00e+00	2150.00
IUUC-Uma-129550	Ustilago maydis	32.69	1.00e-102	368.00
IUUC-Vda-129901	Verticillium dahliae	30.18	1.00e-100	361.00
IUUC-Vpa-130636	Vicugna pacos	97.84	0.00e+00	1041.00
IUUC-Vvi-130891	Vitis vinifera	30.94	2.00e-98	353.00
IUUC-Xtr-132364	Xenopus tropicalis	78.13	0.00e+00	1814.00
IUUC-Xma-133772	Xiphophorus maculatus	84.60	0.00e+00	1549.00
IUUC-Yli-134506	Yarrowia lipolytica	30.68	3.00e-80	293.00
IUUC-Zma-135695	Zea mays	30.82	6.00e-88	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence