iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062938

UUCD1 version

UUC-MoD-00648

Ensembl Protein ID

ENSMODP00000020321.1

UniProt Accession

F7C1Z2; F7C1Z2_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR49

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016248.3	ENSMODT00000020678.2	ENSMODP00000020321.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-26	92.0	283	314
UBD/Beta-Prp	5.60e-42	144.1	146	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           H +++ c af +  +lv+Gs+Dg i +W+ +t
   Q: 283  HREDILCAAFlPPQTLVTGSYDGEILIWNNST 314
           999*******955889************9665 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgh..eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h++++tcv +    ++++++ + +t+  w ++tg++++++ g+  +ae++++ ++p++k l+tgs D++ik+wd+ +g c htl+  
   Q: 146  TSHEKPVTCVLYNSVFRQVISSDTESTVSFWMIDTGQKIKEFTGChgNAEISTMALDPSEKRLLTGSPDGAIKIWDF-NGHCHHTLNVG 233
           57899*******999***************************87622567**************************9.589******77 PP
   S: 94   edsvlslsfsp.sgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......... 166
           +d+++++s     ++++++ ++ r i v+ l+  + +          ++h++ + c+++ p  + lv+Gs+D+ + +W+          
   Q: 234  QDRAVDISQILiLKKTIIVVGWERAITVFRLRDFTPFLVqpeewkGGAQHREDILCAAFLP-PQTLVTGSYDGEILIWNNstenahhvl 321
           77777776666477*******************9999878888888899999999999998.799***************666666666 PP
   S: 167  ................................ktgkllrtltgghtdsvyslsfdsng........................kelvsgs 199
                                           +  + +r+++                                          lvs++
   Q: 322  hpyyqrslhlqlerkpekpgsgdeqedsprrpEKITGVRKWRT--------------DtegnhavmklsflearktitvtggANLVSCG 396
           6666666666666666666666666666666655556666633..............0333334444444444478888888******* PP
   S: 200  ldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlrsgdllktlqlhn...............ssvisvav 272
             g+v++w++ +++ v ++ +h+ + + + +  + +++l++g s g ++iW+++  ++  +++ ++               ++++s  +
   Q: 397  GSGYVRFWNIFRKQLVAEFVAHSGTGSIIMTIdETNQHLITGDSSGCLKIWNIE--EYCLNFNERQvfqppsllrsfqpheDRISSLET 483
           ************************99998888688999*************754..344445554455555677777777799999988 PP
   S: 273  lsfgdnvlvlgse.dskvni 291
              g +vl+ +s+ d++v +
   Q: 484  CVHGSRVLIIASSaDGSVSV 503
           44445555555544999877 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

LAWREKSKQK WIKKTSFNIT QGIHTFDYHS RLNLIATAGL NHRVCLWNPY VASKPTGVLW 60
GHSAPVIAVQ FFTARKQLFS FSKDKVLRLW DIQHQLSIQR IACPFTKSQE FKCLFHFDEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTTGGA GGGAAAAATC CAAGCAGAAG TGGATTAAGA AGACATCCTT CAACATCACC 60
CAGGGCATTC ACACTTTTGA CTACCACTCT CGCCTCAATT TAATTGGTAT GTTGGAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	69.94	0.00e+00	761.00
IUUC-Aca-005140	Anolis carolinensis	59.96	0.00e+00	627.00
IUUC-Ame-011677	Astyanax mexicanus	54.12	2.00e-114	405.00
IUUC-Bta-013449	Bos taurus	64.41	0.00e+00	875.00
IUUC-Cja-019381	Callithrix jacchus	64.71	0.00e+00	880.00
IUUC-Cfa-020449	Canis familiaris	69.38	0.00e+00	780.00
IUUC-Csa-023219	Chlorocebus sabaeus	58.13	1.00e-157	549.00
IUUC-Cho-024437	Choloepus hoffmanni	81.65	2.00e-104	373.00
IUUC-Cin-025263	Ciona intestinalis	49.70	4.00e-146	512.00
IUUC-Dno-029512	Dasypus novemcinctus	61.88	0.00e+00	813.00
IUUC-Dor-030182	Dipodomys ordii	69.25	0.00e+00	681.00
IUUC-Ete-033152	Echinops telfairi	60.74	0.00e+00	801.00
IUUC-Eca-033848	Equus caballus	62.57	3.00e-134	471.00
IUUC-Eeu-034535	Erinaceus europaeus	50.70	2.00e-166	579.00
IUUC-Fca-036363	Felis catus	70.41	0.00e+00	772.00
IUUC-Ggo-045225	Gorilla gorilla	65.95	0.00e+00	894.00
IUUC-Hsa-046739	Homo sapiens	65.67	0.00e+00	894.00
IUUC-Itr-047862	Ictidomys tridecemlineatus	70.45	0.00e+00	693.00
IUUC-Lch-049722	Latimeria chalumnae	62.00	0.00e+00	669.00
IUUC-Loc-052665	Lepisosteus oculatus	59.27	0.00e+00	645.00
IUUC-Laf-054050	Loxodonta africana	60.72	0.00e+00	697.00
IUUC-Meu-056792	Macropus eugenii	76.98	0.00e+00	776.00
IUUC-Mmr-060714	Microcebus murinus	81.21	2.00e-78	286.00
IUUC-Mmu-063645	Mus musculus	60.03	0.00e+00	836.00
IUUC-Mpu-066015	Mustela putorius furo	62.27	0.00e+00	863.00
IUUC-Mlu-068140	Myotis lucifugus	60.18	0.00e+00	788.00
IUUC-Nle-069533	Nomascus leucogenys	64.14	0.00e+00	855.00
IUUC-Opr-070439	Ochotona princeps	59.85	0.00e+00	640.00
IUUC-Oan-073559	Ornithorhynchus anatinus	55.51	4.00e-79	287.00
IUUC-Ocu-074202	Oryctolagus cuniculus	79.45	1.00e-103	370.00
IUUC-Oga-087999	Otolemur garnettii	61.69	0.00e+00	662.00
IUUC-Oar-090438	Ovis aries	63.26	0.00e+00	868.00
IUUC-Ptr-090859	Pan troglodytes	65.67	0.00e+00	863.00
IUUC-Pan-092049	Papio anubis	70.55	0.00e+00	653.00
IUUC-Psi-093625	Pelodiscus sinensis	56.92	0.00e+00	773.00
IUUC-Pab-098444	Pongo abelii	76.27	0.00e+00	718.00
IUUC-Pca-100464	Procavia capensis	53.86	2.00e-132	466.00
IUUC-Pva-102863	Pteropus vampyrus	60.66	0.00e+00	838.00
IUUC-Rno-105493	Rattus norvegicus	60.32	0.00e+00	824.00
IUUC-Sha-107206	Sarcophilus harrisii	69.66	0.00e+00	935.00
IUUC-Sar-113119	Sorex araneus	53.01	1.00e-130	459.00
IUUC-Ssc-116181	Sus scrofa	70.71	0.00e+00	769.00
IUUC-Tsy-119608	Tarsius syrichta	55.49	0.00e+00	705.00
IUUC-Tbe-127509	Tupaia belangeri	67.80	0.00e+00	717.00
IUUC-Ttr-128571	Tursiops truncatus	67.52	0.00e+00	652.00
IUUC-Vpa-130340	Vicugna pacos	59.40	0.00e+00	783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence