iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000006164.2	ENSPANT00000000654.2	ENSPANP00000005146.1
ENSPANG00000006164.2	ENSPANT00000000655.1	ENSPANP00000005969.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-13	49.7	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MRAVLTWRDK AEHCINDIAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDAIQCVS YNPITHQLAS CSSSDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGGCCG TGTTGACGTG GAGAGATAAA GCCGAGCACT GGTGAGAAGC CGGGCGGTCC 60
GCGAAAAGCG GGAGGTCGAG TCCCCGCGAG GACTGCGCGA GCCGCTGCAG CGTGTTTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	92.52	0.00e+00	2263.00
IUUC-Apl-003504	Anas platyrhynchos	82.31	0.00e+00	2047.00
IUUC-Aca-004767	Anolis carolinensis	83.00	0.00e+00	2092.00
IUUC-Ame-011642	Astyanax mexicanus	74.12	0.00e+00	1884.00
IUUC-Bta-012969	Bos taurus	90.51	0.00e+00	2198.00
IUUC-Cel-018670	Caenorhabditis elegans	38.14	0.00e+00	878.00
IUUC-Cja-019249	Callithrix jacchus	91.63	0.00e+00	2249.00
IUUC-Cfa-020915	Canis familiaris	93.25	0.00e+00	2239.00
IUUC-Cpo-021888	Cavia porcellus	74.52	0.00e+00	1824.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	47.88	0.00e+00	1112.00
IUUC-Csa-023533	Chlorocebus sabaeus	99.36	0.00e+00	2431.00
IUUC-Cin-025121	Ciona intestinalis	56.98	0.00e+00	1478.00
IUUC-Csv-026240	Ciona savignyi	57.98	0.00e+00	1431.00
IUUC-Dno-029685	Dasypus novemcinctus	86.16	0.00e+00	2094.00
IUUC-Dme-032005	Drosophila melanogaster	26.74	7.00e-09	56.60
IUUC-Ete-032682	Echinops telfairi	82.90	0.00e+00	1637.00
IUUC-Eca-033831	Equus caballus	93.08	0.00e+00	2313.00
IUUC-Eeu-034919	Erinaceus europaeus	83.25	0.00e+00	978.00
IUUC-Fca-036559	Felis catus	92.84	0.00e+00	2301.00
IUUC-Fal-037340	Ficedula albicollis	80.48	0.00e+00	2006.00
IUUC-Gga-040595	Gallus gallus	81.87	0.00e+00	2065.00
IUUC-Ggo-045356	Gorilla gorilla	94.50	0.00e+00	2388.00
IUUC-Hsa-046135	Homo sapiens	94.59	0.00e+00	2387.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	81.00	0.00e+00	1932.00
IUUC-Lch-050183	Latimeria chalumnae	80.09	0.00e+00	1135.00
IUUC-Loc-052049	Lepisosteus oculatus	78.94	0.00e+00	2005.00
IUUC-Laf-053728	Loxodonta africana	91.80	0.00e+00	2289.00
IUUC-Mcc-054971	Macaca mulatta	96.34	0.00e+00	2418.00
IUUC-Meu-056446	Macropus eugenii	82.61	0.00e+00	2097.00
IUUC-Mga-059296	Meleagris gallopavo	78.87	0.00e+00	2039.00
IUUC-Mmr-061232	Microcebus murinus	89.03	0.00e+00	2206.00
IUUC-Mdo-062115	Monodelphis domestica	90.49	0.00e+00	2254.00
IUUC-Mmu-063664	Mus musculus	91.07	0.00e+00	2298.00
IUUC-Mpu-066136	Mustela putorius furo	88.82	0.00e+00	2189.00
IUUC-Mlu-068238	Myotis lucifugus	89.45	0.00e+00	2236.00
IUUC-Nle-069003	Nomascus leucogenys	94.86	0.00e+00	2309.00
IUUC-Ont-072080	Oreochromis niloticus	75.00	0.00e+00	1920.00
IUUC-Oan-072891	Ornithorhynchus anatinus	81.74	0.00e+00	901.00
IUUC-Ocu-074262	Oryctolagus cuniculus	90.19	0.00e+00	2217.00
IUUC-Ola-086538	Oryzias latipes	72.55	0.00e+00	1824.00
IUUC-Oga-088722	Otolemur garnettii	88.08	0.00e+00	2174.00
IUUC-Oar-089249	Ovis aries	82.70	0.00e+00	1999.00
IUUC-Ptr-090752	Pan troglodytes	90.49	0.00e+00	2243.00
IUUC-Psi-093335	Pelodiscus sinensis	83.00	0.00e+00	2092.00
IUUC-Pma-094520	Petromyzon marinus	67.36	0.00e+00	1588.00
IUUC-Ppa-095600	Physcomitrella patens	63.16	5.00e-39	152.00
IUUC-Pfo-096526	Poecilia formosa	71.63	0.00e+00	1792.00
IUUC-Pab-098428	Pongo abelii	96.88	0.00e+00	1210.00
IUUC-Pca-100233	Procavia capensis	70.27	0.00e+00	951.00
IUUC-Pva-103064	Pteropus vampyrus	79.27	0.00e+00	1916.00
IUUC-Rno-105764	Rattus norvegicus	91.47	0.00e+00	2273.00
IUUC-Sha-106649	Sarcophilus harrisii	90.09	0.00e+00	2230.00
IUUC-Smo-109287	Selaginella moellendorffii	39.92	0.00e+00	872.00
IUUC-Tgu-116870	Taeniopygia guttata	81.61	0.00e+00	1991.00
IUUC-Tru-118661	Takifugu rubripes	70.34	0.00e+00	1789.00
IUUC-Tsy-119640	Tarsius syrichta	93.03	3.00e-110	393.00
IUUC-Tni-120812	Tetraodon nigroviridis	71.67	0.00e+00	1795.00
IUUC-Ttr-128862	Tursiops truncatus	88.38	0.00e+00	2247.00
IUUC-Vpa-130049	Vicugna pacos	86.49	1.00e-153	537.00
IUUC-Xtr-131914	Xenopus tropicalis	77.37	0.00e+00	1950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence