iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053669

Ensembl Protein ID

ENSLAFP00000004830.4

UniProt Accession

G3SWV0; G3SWV0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

STXBP5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005764.4	ENSLAFT00000005764.4	ENSLAFP00000004830.4
ENSLAFG00000005764.4	ENSLAFT00000032445.1	ENSLAFP00000019932.1
ENSLAFG00000005764.4	ENSLAFT00000028167.1	ENSLAFP00000018980.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-11	44.2	109	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf..sdtllvsGsdDgtikvWDlrtgv 34
            v  l+f  +++ lvs+s D t+++W+lr+ +
   Q: 109  AVLQLQFliNEGALVSASSDDTLHLWNLRQKR 140
           4888999999999***************9865 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MKKFNFRKVL DGLTASSPGS GSNTGSGAGS GPGHPAGTAG LLREEIQETL TSDYFQLCKT 60
VRHGFPYQPT ALAFDPVQKI LAIGTRTGAI RILGRPGVDC YCQHESGAAV LQLQFLINEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAGT TTAATTTCCG AAAAGTTTTG GATGGCTTAA CTGCCTCTTC CCCTGGCAGT 60
GGCAGCAACA CTGGTAGTGG GGCTGGAAGT GGTCCCGGGC ACCCTGCAGG GACCGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR001388--Synaptobrevin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50892--V_SNARE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08596--Lgl_C
PF08366--LLGL
PF00400--WD40

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0042593--P:glucose homeostasis
GO:0046676--P:negative regulation of insulin secretion
GO:0050714--P:positive regulation of protein secretion
GO:0017157--P:regulation of exocytosis
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001923	Ailuropoda melanoleuca	63.40	0.00e+00	1502.00
IUUC-Atr-002583	Amborella trichopoda	28.36	7.00e-21	96.30
IUUC-Apl-003824	Anas platyrhynchos	80.24	0.00e+00	1711.00
IUUC-Aca-004971	Anolis carolinensis	77.76	0.00e+00	1660.00
IUUC-Acl-008044	Aspergillus clavatus	22.22	1.00e-12	68.90
IUUC-Afl-008612	Aspergillus flavus	23.61	7.00e-14	73.20
IUUC-Ani-009223	Aspergillus nidulans	22.33	9.00e-15	75.90
IUUC-Aor-010078	Aspergillus oryzae	23.61	7.00e-14	73.20
IUUC-Ame-010663	Astyanax mexicanus	61.96	0.00e+00	1456.00
IUUC-Bgr-012214	Blumeria graminis	23.75	7.00e-10	59.70
IUUC-Bta-013516	Bos taurus	94.09	0.00e+00	2168.00
IUUC-Bol-015788	Brassica oleracea	23.58	3.00e-21	97.80
IUUC-Cja-019607	Callithrix jacchus	94.05	0.00e+00	1917.00
IUUC-Cfa-020684	Canis familiaris	93.68	0.00e+00	2167.00
IUUC-Cpo-021931	Cavia porcellus	89.08	0.00e+00	1972.00
IUUC-Csa-024071	Chlorocebus sabaeus	93.68	0.00e+00	2244.00
IUUC-Cho-025086	Choloepus hoffmanni	86.68	0.00e+00	1985.00
IUUC-Dre-028232	Danio rerio	68.95	0.00e+00	1542.00
IUUC-Dno-029242	Dasypus novemcinctus	93.76	0.00e+00	2179.00
IUUC-Dor-030660	Dipodomys ordii	85.41	0.00e+00	1973.00
IUUC-Dse-031263	Dothistroma septosporum	24.55	4.00e-13	70.50
IUUC-Ete-033006	Echinops telfairi	80.42	0.00e+00	1233.00
IUUC-Eeu-034943	Erinaceus europaeus	98.02	0.00e+00	845.00
IUUC-Fca-036345	Felis catus	90.07	0.00e+00	1459.00
IUUC-Fal-036915	Ficedula albicollis	82.97	0.00e+00	1978.00
IUUC-Gmo-039272	Gadus morhua	61.08	0.00e+00	1446.00
IUUC-Gga-040529	Gallus gallus	85.30	0.00e+00	2009.00
IUUC-Gac-042416	Gasterosteus aculeatus	69.92	0.00e+00	1579.00
IUUC-Gma-043398	Glycine max	32.51	7.00e-20	93.20
IUUC-Ggo-044575	Gorilla gorilla	94.01	0.00e+00	2261.00
IUUC-Hsa-045781	Homo sapiens	94.27	0.00e+00	2264.00
IUUC-Itr-048722	Ictidomys tridecemlineatus	57.58	0.00e+00	1222.00
IUUC-Lch-050258	Latimeria chalumnae	80.64	0.00e+00	1505.00
IUUC-Loc-051905	Lepisosteus oculatus	76.13	0.00e+00	1286.00
IUUC-Mcc-055188	Macaca mulatta	93.68	0.00e+00	2244.00
IUUC-Meu-056246	Macropus eugenii	81.59	0.00e+00	880.00
IUUC-Mga-059965	Meleagris gallopavo	64.35	0.00e+00	1385.00
IUUC-Mmr-061273	Microcebus murinus	86.64	0.00e+00	2082.00
IUUC-Mdo-062223	Monodelphis domestica	91.27	0.00e+00	1933.00
IUUC-Mmu-063800	Mus musculus	92.07	0.00e+00	2204.00
IUUC-Mac-065436	Musa acuminata	30.08	1.00e-13	72.00
IUUC-Mpu-066690	Mustela putorius furo	61.32	0.00e+00	1228.00
IUUC-Mlu-067278	Myotis lucifugus	92.75	0.00e+00	2203.00
IUUC-Nfi-068318	Neosartorya fischeri	23.93	1.00e-13	72.00
IUUC-Nle-069733	Nomascus leucogenys	94.18	0.00e+00	2262.00
IUUC-Opr-070840	Ochotona princeps	77.42	0.00e+00	1196.00
IUUC-Ont-072051	Oreochromis niloticus	62.57	0.00e+00	1499.00
IUUC-Oan-073020	Ornithorhynchus anatinus	60.64	0.00e+00	1196.00
IUUC-Ocu-074214	Oryctolagus cuniculus	93.93	0.00e+00	2197.00
IUUC-Ola-087301	Oryzias latipes	72.45	0.00e+00	1538.00
IUUC-Oga-089148	Otolemur garnettii	91.57	0.00e+00	2175.00
IUUC-Oar-090261	Ovis aries	93.94	0.00e+00	2132.00
IUUC-Ptr-090697	Pan troglodytes	94.27	0.00e+00	2264.00
IUUC-Pan-092899	Papio anubis	93.69	0.00e+00	2239.00
IUUC-Psi-093249	Pelodiscus sinensis	84.72	0.00e+00	1938.00
IUUC-Pfo-096143	Poecilia formosa	60.95	0.00e+00	1437.00
IUUC-Pab-097774	Pongo abelii	89.37	0.00e+00	1665.00
IUUC-Pca-100605	Procavia capensis	56.69	0.00e+00	1042.00
IUUC-Pva-102704	Pteropus vampyrus	82.74	0.00e+00	1855.00
IUUC-Pte-104412	Pyrenophora teres	24.06	2.00e-16	81.30
IUUC-Pyt-104770	Pyrenophora triticirepentis	24.06	5.00e-16	80.10
IUUC-Rno-105297	Rattus norvegicus	92.94	0.00e+00	2063.00
IUUC-Sha-107086	Sarcophilus harrisii	84.99	0.00e+00	1849.00
IUUC-Sly-111338	Solanum lycopersicum	27.91	2.00e-21	96.70
IUUC-Stu-112417	Solanum tuberosum	28.68	4.00e-22	99.00
IUUC-Sar-113111	Sorex araneus	58.08	0.00e+00	1274.00
IUUC-Ssc-115307	Sus scrofa	63.16	0.00e+00	1493.00
IUUC-Tgu-117382	Taeniopygia guttata	83.50	0.00e+00	1701.00
IUUC-Tru-118317	Takifugu rubripes	72.38	0.00e+00	1603.00
IUUC-Tsy-119322	Tarsius syrichta	88.10	0.00e+00	1347.00
IUUC-Tni-120362	Tetraodon nigroviridis	60.39	0.00e+00	1360.00
IUUC-Tca-121778	Theobroma cacao	23.86	3.00e-20	94.40
IUUC-Ttr-129239	Tursiops truncatus	93.80	0.00e+00	2116.00
IUUC-Vpa-130524	Vicugna pacos	87.52	0.00e+00	1964.00
IUUC-Xtr-132634	Xenopus tropicalis	74.41	0.00e+00	1776.00
IUUC-Xma-133316	Xiphophorus maculatus	66.42	0.00e+00	1606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence