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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Mmu-063724
Ensembl Protein ID ENSMUSP00000000450.3
UniProt Accession Q6GU14; Q6GU14_MOUSE
Genbank Protein ID AAH21798.1; AAO45097.1; AAO45098.1; AAP42200.1; BAF80899.1; BAF80900.1
Protein Name Peroxisome proliferator activated receptor gamma; Peroxisome proliferator-activated receptor gamma; Peroxisome proliferator-activated receptor gamma isoform 2; Peroxisome proliferator-activated receptor gamma transcript 2
Genbank Nucleotide ID AC153828; AY208183; AY208184; AY243585; AB256529; AB256530
Gene Name Pparg
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000000440.12 ENSMUST00000000450.4 ENSMUSP00000000450.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
BioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 96.24 0.00e+00 986.00 IUUC-Hsa-046916
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Protein Sequence
(Fasta)
MGETLGDSPV DPEHGAFADA LPMSTSQEIT MVDTEMPFWP TNFGISSVDL SVMEDHSHSF 60
DIKPFTTVDF SSISAPHYED IPFTRADPMV ADYKYDLKLQ EYQSAIKVEP ASPPYYSEKT 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-063724|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCTCACCC TGGGCACCGC CCCCGGTCCG GCCGGGTGGC TCGGCTCGGC TCCTCCGGTC 60
CGCGGCCGGC CAGGCGGGGC CCGTCGCACT CAGAGCGGCA GCCGCCTGGG GCGCTCGGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-063724|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0031100--P:animal organ regeneration
GO:0048469--P:cell maturation
GO:0071455--P:cellular response to hyperoxia
GO:0032869--P:cellular response to insulin stimulus
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0071300--P:cellular response to retinoic acid
GO:0071306--P:cellular response to vitamin E
GO:0019395--P:fatty acid oxidation
GO:0042593--P:glucose homeostasis
GO:0007507--P:heart development
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0002674--P:negative regulation of acute inflammatory response
GO:0030308--P:negative regulation of cell growth
GO:0010887--P:negative regulation of cholesterol storage
GO:0032966--P:negative regulation of collagen biosynthetic process
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:2000230--P:negative regulation of pancreatic stellate cell proliferation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0051974--P:negative regulation of telomerase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0048714--P:positive regulation of oligodendrocyte differentiation
GO:0060100--P:positive regulation of phagocytosis, engulfment
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0045598--P:regulation of fat cell differentiation
GO:0031000--P:response to caffeine
GO:0009409--P:response to cold
GO:0042493--P:response to drug
GO:0043627--P:response to estrogen
GO:0035902--P:response to immobilization stress
GO:0055098--P:response to low-density lipoprotein particle
GO:0009612--P:response to mechanical stimulus
GO:1901558--P:response to metformin
GO:0042594--P:response to starvation
GO:0033189--P:response to vitamin A
GO:0006351--P:transcription, DNA-templated

KEGG mmu:19016
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001214 Ailuropoda melanoleuca 94.26 0.00e+00 954.00
IUUC-Aca-005129 Anolis carolinensis 88.43 0.00e+00 869.00
IUUC-Ame-010818 Astyanax mexicanus 65.17 0.00e+00 640.00
IUUC-Bta-013226 Bos taurus 95.05 0.00e+00 970.00
IUUC-Cja-019236 Callithrix jacchus 96.04 0.00e+00 983.00
IUUC-Cfa-020281 Canis familiaris 96.63 0.00e+00 988.00
IUUC-Cpo-021587 Cavia porcellus 95.25 0.00e+00 932.00
IUUC-Csa-023400 Chlorocebus sabaeus 98.32 0.00e+00 945.00
IUUC-Cho-024593 Choloepus hoffmanni 84.36 0.00e+00 837.00
IUUC-Dre-028176 Danio rerio 61.05 1.00e-153 536.00
IUUC-Dno-029063 Dasypus novemcinctus 93.08 0.00e+00 940.00
IUUC-Ete-032520 Echinops telfairi 93.07 0.00e+00 940.00
IUUC-Fca-035935 Felis catus 96.44 0.00e+00 986.00
IUUC-Fal-037524 Ficedula albicollis 91.37 0.00e+00 877.00
IUUC-Gga-041223 Gallus gallus 92.42 0.00e+00 885.00
IUUC-Gac-042156 Gasterosteus aculeatus 61.75 0.00e+00 632.00
IUUC-Ggo-045265 Gorilla gorilla 96.63 0.00e+00 988.00
IUUC-Hsa-046916 Homo sapiens 96.24 0.00e+00 986.00
IUUC-Lch-049759 Latimeria chalumnae 79.80 0.00e+00 676.00
IUUC-Loc-051870 Lepisosteus oculatus 73.55 0.00e+00 741.00
IUUC-Laf-054483 Loxodonta africana 94.46 0.00e+00 963.00
IUUC-Meu-056587 Macropus eugenii 94.00 0.00e+00 919.00
IUUC-Mga-059530 Meleagris gallopavo 92.42 0.00e+00 885.00
IUUC-Mmr-060576 Microcebus murinus 94.85 0.00e+00 972.00
IUUC-Mdo-061854 Monodelphis domestica 97.68 0.00e+00 931.00
IUUC-Mpu-066888 Mustela putorius furo 98.32 0.00e+00 978.00
IUUC-Mlu-067978 Myotis lucifugus 95.64 0.00e+00 1011.00
IUUC-Nle-070069 Nomascus leucogenys 96.24 0.00e+00 986.00
IUUC-Opr-070630 Ochotona princeps 93.38 0.00e+00 791.00
IUUC-Ont-071399 Oreochromis niloticus 58.89 2.00e-178 619.00
IUUC-Ocu-074862 Oryctolagus cuniculus 97.27 0.00e+00 941.00
IUUC-Ola-087266 Oryzias latipes 56.05 2.00e-158 551.00
IUUC-Oga-089143 Otolemur garnettii 94.65 0.00e+00 974.00
IUUC-Oar-089725 Ovis aries 95.45 0.00e+00 972.00
IUUC-Ptr-091580 Pan troglodytes 96.44 0.00e+00 988.00
IUUC-Psi-093041 Pelodiscus sinensis 90.36 0.00e+00 863.00
IUUC-Pfo-097438 Poecilia formosa 58.36 4.00e-176 611.00
IUUC-Pab-098333 Pongo abelii 97.27 0.00e+00 933.00
IUUC-Pca-100861 Procavia capensis 96.44 0.00e+00 929.00
IUUC-Pva-102186 Pteropus vampyrus 86.14 0.00e+00 859.00
IUUC-Rno-105583 Rattus norvegicus 99.60 0.00e+00 1016.00
IUUC-Sha-107484 Sarcophilus harrisii 96.87 0.00e+00 934.00
IUUC-Sar-112996 Sorex araneus 84.29 0.00e+00 643.00
IUUC-Ssc-115945 Sus scrofa 96.04 0.00e+00 976.00
IUUC-Tsy-119098 Tarsius syrichta 86.73 0.00e+00 857.00
IUUC-Tni-120902 Tetraodon nigroviridis 58.93 2.00e-171 595.00
IUUC-Tbe-127225 Tupaia belangeri 74.85 0.00e+00 707.00
IUUC-Ttr-129292 Tursiops truncatus 96.24 0.00e+00 982.00
IUUC-Vpa-130378 Vicugna pacos 91.33 0.00e+00 786.00
Created Date 25-Jun-2017

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