iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026939

Ensembl Protein ID

AAW45887

UniProt Accession

P0CS30; Q55LG3; Q5KA32; CIAO1_CRYNJ

Genbank Protein ID

AAW45887.1

Protein Name

Probable cytosolic iron-sulfur protein assembly protein 1

Genbank Nucleotide ID

AE017350

Gene Name

CIA1; CNJ03240

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNJ03240	AAW45887	AAW45887

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-42	138.3	72	101
UBD/Beta-Prp	8.10e-44	148.4	139	435

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+  v+++a+ +d ++l+sGs D t+ vW+
   Q: 72   HKRTVRSIAWsPDgRTLASGSFDSTVGVWE 101
           999********99999*************7 PP

UBD/Beta-Prp

   S: 41   tgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirv.wdl.etgqclee..... 131
           ++ ++ +l+ghe+e ++v fs+dg +l+++s+D+ + vw+++   +++c+ ++ +h+++v s++++p  + l+s+s d++i++ +d  ++++c+ +     
   Q: 139  EWECVTTLEGHESECKSVGFSSDGALLASCSRDKSVWVWEVQpdaDFECIAVMMEHSQDVKSIAWHPHEEILASASYDSYIHLaYDDpDSDWCIFQklhps 239
           577899*********************************999999***************************************887257888877999** PP
   S: 132  ...................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.......ktgkllrtltgghtdsvyslsfds 190
                                              +  ++d++v+c++++pdg+ l+sG++++ +rlW+        +++++l+t   +h +sv sls+++
   Q: 240  lpstpltipstspshlidalvpteeekkaeaelqvPPLEEDETVWCLAWSPDGRWLASGGDNGGIRLWQRtgsqpdsAFKEILHTA--AHSRSVFSLSWSP 338
           ***********************************9999*******************************9998888888888887..6*********887 PP
   S: 191  ng..............kelvsgsldgtvklwdlq........tgec...............vrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
                             l+s+++dg++++w++         ++e+                + +n+ ++  ++vr + +    l s+++Dgs+++W
   Q: 339  PYpsaesagstdstdlGMLASAGEDGKIIIWQITvppspssaSQEIdneqisirpiaaqkdAHGVNDINSVAWCVREDkKGWGMLSSAGDDGSVKVW 435
           667778888889989999****************9999888733334444455554433335555555577777777733445677777******** PP

Organism

Cryptococcus neoformans

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MLRLQSLGSL PAHAEPAWTV SFNPTRSLLA SCSTDRTIRL YSYIIPSSSD GLPSQDDSQA 60
VFSLAKVIET DHKRTVRSIA WSPDGRTLAS GSFDSTVGVW EEVIPLSDDE EEEDEGAQGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTCGGC TCCAATCCCT GGGTTCCCTC CCGGCCCATG CCGAACCAGC TTGGACAGTA 60
TCTTTCAACC CTACCCGCTC TCTCCTCGCA TCATGCTCCA CAGATCGCAC AATCCGTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

KEGG

cne:CNJ03240

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	27.81	6.00e-40	157.00
IUUC-Aml-001317	Ailuropoda melanoleuca	31.91	9.00e-40	155.00
IUUC-Atr-003029	Amborella trichopoda	31.83	1.00e-47	181.00
IUUC-Aly-006458	Arabidopsis lyrata	31.60	6.00e-44	169.00
IUUC-Ath-006671	Arabidopsis thaliana	32.10	1.00e-44	171.00
IUUC-Ago-007820	Ashbya gossypii	29.89	1.00e-39	154.00
IUUC-Acl-008042	Aspergillus clavatus	29.96	1.00e-40	158.00
IUUC-Afl-008639	Aspergillus flavus	32.75	1.00e-45	175.00
IUUC-Afu-008899	Aspergillus fumigatus	28.14	2.00e-41	160.00
IUUC-Ani-009453	Aspergillus nidulans	30.38	8.00e-45	172.00
IUUC-Ang-009758	Aspergillus niger	30.21	4.00e-40	156.00
IUUC-Aor-010212	Aspergillus oryzae	32.75	1.00e-45	175.00
IUUC-Ate-010314	Aspergillus terreus	29.79	3.00e-42	163.00
IUUC-Ame-010676	Astyanax mexicanus	29.25	2.00e-43	167.00
IUUC-Bgr-012095	Blumeria graminis	26.77	4.00e-31	127.00
IUUC-Bta-012884	Bos taurus	30.84	7.00e-37	145.00
IUUC-Bci-013622	Botrytis cinerea	28.45	8.00e-30	122.00
IUUC-Bdi-014614	Brachypodium distachyon	29.69	2.00e-48	183.00
IUUC-Bol-016439	Brassica oleracea	27.48	1.00e-40	158.00
IUUC-Bra-016830	Brassica rapa	27.54	1.00e-39	154.00
IUUC-Cel-018709	Caenorhabditis elegans	28.90	2.00e-35	140.00
IUUC-Cja-019822	Callithrix jacchus	32.13	4.00e-40	156.00
IUUC-Cfa-020823	Canis familiaris	32.21	9.00e-41	158.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	30.68	6.00e-45	172.00
IUUC-Csa-023754	Chlorocebus sabaeus	32.21	2.00e-40	157.00
IUUC-Cin-025395	Ciona intestinalis	31.24	8.00e-45	172.00
IUUC-Csv-025943	Ciona savignyi	30.77	1.00e-45	174.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	30.35	3.00e-33	134.00
IUUC-Cme-027239	Cyanidioschyzon merolae	32.24	8.00e-36	142.00
IUUC-Dre-028172	Danio rerio	29.65	2.00e-44	170.00
IUUC-Dno-029472	Dasypus novemcinctus	31.85	1.00e-33	134.00
IUUC-Dor-031134	Dipodomys ordii	33.66	2.00e-25	107.00
IUUC-Dse-031535	Dothistroma septosporum	28.94	2.00e-39	154.00
IUUC-Dme-032020	Drosophila melanogaster	30.29	7.00e-47	178.00
IUUC-Eca-033700	Equus caballus	31.98	3.00e-40	157.00
IUUC-Eeu-035010	Erinaceus europaeus	31.01	3.00e-36	143.00
IUUC-Fca-036309	Felis catus	28.76	8.00e-34	135.00
IUUC-Fal-037243	Ficedula albicollis	31.72	7.00e-26	108.00
IUUC-Fox-038058	Fusarium oxysporum	30.73	5.00e-30	124.00
IUUC-Fso-038459	Fusarium solani	30.64	8.00e-31	125.00
IUUC-Gmo-039375	Gadus morhua	30.97	3.00e-36	143.00
IUUC-Ggr-040002	Gaeumannomyces graminis	29.19	9.00e-29	119.00
IUUC-Gga-040294	Gallus gallus	30.53	3.00e-29	120.00
IUUC-Gac-042499	Gasterosteus aculeatus	30.25	2.00e-33	134.00
IUUC-Gma-043543	Glycine max	30.22	5.00e-51	192.00
IUUC-Ggo-045181	Gorilla gorilla	32.21	2.00e-40	157.00
IUUC-Hsa-046528	Homo sapiens	32.21	2.00e-40	157.00
IUUC-Hvu-047341	Hordeum vulgare	39.08	3.00e-43	166.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	31.98	5.00e-40	156.00
IUUC-Kpa-049353	Komagataella pastoris	28.11	1.00e-38	151.00
IUUC-Lch-049763	Latimeria chalumnae	31.76	3.00e-42	163.00
IUUC-Lpe-051500	Leersia perrieri	31.13	2.00e-45	174.00
IUUC-Loc-052021	Lepisosteus oculatus	30.30	4.00e-34	136.00
IUUC-Lma-053331	Leptosphaeria maculans	29.50	4.00e-42	164.00
IUUC-Laf-054558	Loxodonta africana	31.76	6.00e-40	155.00
IUUC-Mcc-055374	Macaca mulatta	32.21	2.00e-40	157.00
IUUC-Meu-056042	Macropus eugenii	32.18	1.00e-28	117.00
IUUC-Mor-057187	Magnaporthe oryzae	30.12	3.00e-33	134.00
IUUC-Mtr-058072	Medicago truncatula	31.33	3.00e-52	196.00
IUUC-Mla-059108	Melampsora laricipopulina	32.68	3.00e-57	213.00
IUUC-Mga-059370	Meleagris gallopavo	27.45	1.00e-14	71.60
IUUC-Mvi-060495	Microbotryum violaceum	33.14	3.00e-56	210.00
IUUC-Mmr-060902	Microcebus murinus	31.98	2.00e-40	157.00
IUUC-Mdo-062510	Monodelphis domestica	31.39	4.00e-38	149.00
IUUC-Mmu-063575	Mus musculus	31.46	5.00e-38	149.00
IUUC-Mac-065322	Musa acuminata	29.24	5.00e-51	192.00
IUUC-Mpu-065925	Mustela putorius furo	31.40	1.00e-39	155.00
IUUC-Mlu-067755	Myotis lucifugus	31.53	8.00e-40	155.00
IUUC-Nfi-068327	Neosartorya fischeri	30.30	2.00e-41	161.00
IUUC-Ncr-068845	Neurospora crassa	34.38	6.00e-19	86.70
IUUC-Nle-069406	Nomascus leucogenys	32.06	3.00e-38	150.00
IUUC-Opr-070416	Ochotona princeps	39.41	3.00e-25	107.00
IUUC-Ont-071936	Oreochromis niloticus	30.37	7.00e-36	142.00
IUUC-Oan-073452	Ornithorhynchus anatinus	35.71	3.00e-19	85.50
IUUC-Ocu-074791	Oryctolagus cuniculus	31.67	8.00e-39	152.00
IUUC-Oba-075636	Oryza barthii	30.20	5.00e-49	186.00
IUUC-Obr-076742	Oryza brachyantha	32.98	3.00e-46	176.00
IUUC-Ogl-077766	Oryza glaberrima	30.20	5.00e-49	186.00
IUUC-Ogu-079039	Oryza glumaepatula	30.43	1.00e-49	188.00
IUUC-Oin-079315	Oryza indica	31.19	1.00e-44	171.00
IUUC-Olo-080669	Oryza longistaminata	27.94	1.00e-42	164.00
IUUC-Ome-081490	Oryza meridionalis	30.43	6.00e-49	186.00
IUUC-Oni-082572	Oryza nivara	30.20	5.00e-49	186.00
IUUC-Opu-083732	Oryza punctata	30.39	2.00e-49	187.00
IUUC-Oru-084763	Oryza rufipogon	30.20	5.00e-49	186.00
IUUC-Osa-085372	Oryza sativa	30.20	5.00e-49	186.00
IUUC-Ola-087379	Oryzias latipes	29.16	3.00e-33	134.00
IUUC-Olu-087801	Ostreococcus lucimarinus	28.01	6.00e-28	115.00
IUUC-Oga-089076	Otolemur garnettii	31.75	2.00e-40	157.00
IUUC-Oar-090022	Ovis aries	31.52	1.00e-37	147.00
IUUC-Ptr-090809	Pan troglodytes	32.21	2.00e-40	157.00
IUUC-Pan-091685	Papio anubis	32.21	2.00e-40	158.00
IUUC-Psi-093046	Pelodiscus sinensis	30.43	1.00e-37	148.00
IUUC-Pma-094181	Petromyzon marinus	30.65	1.00e-47	181.00
IUUC-Pno-094882	Phaeosphaeria nodorum	31.51	8.00e-46	176.00
IUUC-Ppa-095172	Physcomitrella patens	31.74	7.00e-47	179.00
IUUC-Pfo-096396	Poecilia formosa	30.12	6.00e-34	135.00
IUUC-Pab-098427	Pongo abelii	32.21	6.00e-40	155.00
IUUC-Pop-100016	Populus trichocarpa	28.79	6.00e-48	182.00
IUUC-Pca-101048	Procavia capensis	31.31	1.00e-38	151.00
IUUC-Ppe-102050	Prunus persica	29.24	6.00e-48	182.00
IUUC-Pva-103117	Pteropus vampyrus	31.08	1.00e-37	148.00
IUUC-Pgr-103307	Puccinia graminis	32.78	5.00e-56	209.00
IUUC-Ptt-103938	Puccinia triticina	34.20	1.00e-43	167.00
IUUC-Pte-104315	Pyrenophora teres	29.25	1.00e-42	165.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	29.03	6.00e-42	162.00
IUUC-Rno-105523	Rattus norvegicus	31.84	2.00e-38	150.00
IUUC-Sce-106297	Saccharomyces cerevisiae	29.93	3.00e-43	167.00
IUUC-Sha-106981	Sarcophilus harrisii	31.68	1.00e-31	128.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	30.32	2.00e-45	175.00
IUUC-Spo-108214	Schizosaccharomyces pombe	29.51	1.00e-44	172.00
IUUC-Smo-108753	Selaginella moellendorffii	29.63	2.00e-47	181.00
IUUC-Sit-110663	Setaria italica	29.98	3.00e-47	180.00
IUUC-Sly-110898	Solanum lycopersicum	29.46	6.00e-47	179.00
IUUC-Stu-112647	Solanum tuberosum	30.64	1.00e-41	161.00
IUUC-Sbi-114288	Sorghum bicolor	30.87	3.00e-49	186.00
IUUC-Sre-115065	Sporisorium reilianum	38.22	9.00e-79	285.00
IUUC-Ssc-115960	Sus scrofa	30.02	5.00e-40	156.00
IUUC-Tru-118382	Takifugu rubripes	31.01	3.00e-47	180.00
IUUC-Tsy-119585	Tarsius syrichta	29.05	1.00e-30	124.00
IUUC-Tni-120133	Tetraodon nigroviridis	30.44	9.00e-41	158.00
IUUC-Tca-121167	Theobroma cacao	30.07	1.00e-45	175.00
IUUC-Tre-122119	Trichoderma reesei	30.09	9.00e-28	115.00
IUUC-Tvi-122407	Trichoderma virens	29.27	6.00e-33	133.00
IUUC-Tae-124928	Triticum aestivum	30.58	1.00e-46	178.00
IUUC-Tur-126176	Triticum urartu	31.12	2.00e-39	154.00
IUUC-Tme-127095	Tuber melanosporum	31.90	1.00e-47	181.00
IUUC-Tbe-128004	Tupaia belangeri	31.53	3.00e-39	153.00
IUUC-Ttr-129284	Tursiops truncatus	30.61	5.00e-35	139.00
IUUC-Uma-129527	Ustilago maydis	37.01	8.00e-77	278.00
IUUC-Vda-129854	Verticillium dahliae	31.17	3.00e-32	130.00
IUUC-Vpa-130681	Vicugna pacos	44.37	1.00e-20	91.30
IUUC-Vvi-131004	Vitis vinifera	29.80	1.00e-49	187.00
IUUC-Xtr-131928	Xenopus tropicalis	31.46	2.00e-37	147.00
IUUC-Xma-134290	Xiphophorus maculatus	29.65	1.00e-32	132.00
IUUC-Yli-134364	Yarrowia lipolytica	30.98	6.00e-47	179.00
IUUC-Zma-135658	Zea mays	31.10	9.00e-49	185.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence