iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000006307.16	ENSMUST00000006470.13	ENSMUSP00000006470.7
ENSMUSG00000006307.16	ENSMUST00000108154.8	ENSMUSP00000103789.2
ENSMUSG00000006307.16	ENSMUST00000131002.1	ENSMUSP00000118486.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
miRNAMap	RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLM	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.40e-27	96.0	1256	1309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++ +  wiC+ C ++
   Q: 1256 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRRRrhWICSACVRC 1309
           58********************************.55554444444******876 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG GGAAGPGGAE 60
PGEDTALLRL LGLRRGLRRL RRLWAGARVQ RGRGRGRGRG WGPNRGCMPE EESSDGESEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCCAAGA TGGCGGCGGC GGCGGGCGGC GGCAGTTGCC CCGGGCCTGG CTCCGCACGG 60
GGCCGCTTCC CGGGCCGGCC GCGGGGTTCC GGCGGGGGCG GGGGCCGCGG CGGCCGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	88.32	0.00e+00	3142.00
IUUC-Aca-004718	Anolis carolinensis	55.29	0.00e+00	2107.00
IUUC-Ame-010705	Astyanax mexicanus	44.03	0.00e+00	933.00
IUUC-Bta-013578	Bos taurus	91.06	0.00e+00	2878.00
IUUC-Bdi-014882	Brachypodium distachyon	33.33	1.00e-27	118.00
IUUC-Bra-017422	Brassica rapa	33.81	8.00e-28	119.00
IUUC-Cja-019138	Callithrix jacchus	87.56	0.00e+00	3201.00
IUUC-Cfa-020020	Canis familiaris	89.73	0.00e+00	3107.00
IUUC-Cpo-021552	Cavia porcellus	89.08	0.00e+00	3185.00
IUUC-Csa-024216	Chlorocebus sabaeus	90.05	0.00e+00	2466.00
IUUC-Cho-024565	Choloepus hoffmanni	75.78	4.00e-164	573.00
IUUC-Dre-027440	Danio rerio	48.21	0.00e+00	775.00
IUUC-Dno-029583	Dasypus novemcinctus	88.21	0.00e+00	3174.00
IUUC-Dor-030903	Dipodomys ordii	87.56	0.00e+00	2170.00
IUUC-Dme-032023	Drosophila melanogaster	46.99	2.00e-92	336.00
IUUC-Eca-034026	Equus caballus	93.40	0.00e+00	1925.00
IUUC-Eeu-034687	Erinaceus europaeus	90.96	0.00e+00	1108.00
IUUC-Fca-036311	Felis catus	89.97	0.00e+00	3200.00
IUUC-Gmo-039265	Gadus morhua	45.29	0.00e+00	827.00
IUUC-Gac-042202	Gasterosteus aculeatus	49.38	0.00e+00	764.00
IUUC-Ggo-044791	Gorilla gorilla	91.56	0.00e+00	2096.00
IUUC-Hsa-046988	Homo sapiens	89.93	0.00e+00	2417.00
IUUC-Hvu-047762	Hordeum vulgare	36.57	4.00e-20	92.80
IUUC-Itr-048907	Ictidomys tridecemlineatus	91.80	0.00e+00	3344.00
IUUC-Lpe-051476	Leersia perrieri	31.51	3.00e-24	107.00
IUUC-Loc-052252	Lepisosteus oculatus	54.24	0.00e+00	786.00
IUUC-Laf-053703	Loxodonta africana	91.24	0.00e+00	2152.00
IUUC-Mcc-054782	Macaca mulatta	89.03	0.00e+00	2452.00
IUUC-Meu-056046	Macropus eugenii	78.53	0.00e+00	1870.00
IUUC-Mmr-061316	Microcebus murinus	89.00	0.00e+00	2800.00
IUUC-Mdo-062648	Monodelphis domestica	79.14	0.00e+00	2703.00
IUUC-Mac-064935	Musa acuminata	32.02	5.00e-30	126.00
IUUC-Mpu-066710	Mustela putorius furo	89.71	0.00e+00	3147.00
IUUC-Mlu-067559	Myotis lucifugus	88.57	0.00e+00	2412.00
IUUC-Nle-070085	Nomascus leucogenys	87.52	0.00e+00	2136.00
IUUC-Opr-071148	Ochotona princeps	85.78	0.00e+00	3179.00
IUUC-Ont-071626	Oreochromis niloticus	45.68	0.00e+00	913.00
IUUC-Ocu-074475	Oryctolagus cuniculus	86.90	0.00e+00	3081.00
IUUC-Obr-076458	Oryza brachyantha	34.48	3.00e-28	120.00
IUUC-Ogl-077851	Oryza glaberrima	36.26	2.00e-28	120.00
IUUC-Ogu-078706	Oryza glumaepatula	36.26	1.00e-28	122.00
IUUC-Oin-079802	Oryza indica	31.43	2.00e-23	104.00
IUUC-Osa-085421	Oryza sativa	36.26	4.00e-28	120.00
IUUC-Ola-086609	Oryzias latipes	52.09	0.00e+00	766.00
IUUC-Oga-088140	Otolemur garnettii	89.94	0.00e+00	3173.00
IUUC-Oar-089447	Ovis aries	90.89	0.00e+00	1993.00
IUUC-Ptr-090902	Pan troglodytes	89.93	0.00e+00	2423.00
IUUC-Pan-091930	Papio anubis	90.05	0.00e+00	2475.00
IUUC-Ppa-095221	Physcomitrella patens	36.54	6.00e-31	129.00
IUUC-Pfo-096884	Poecilia formosa	46.75	0.00e+00	910.00
IUUC-Pab-098404	Pongo abelii	76.86	0.00e+00	1622.00
IUUC-Pop-099585	Populus trichocarpa	33.83	1.00e-26	115.00
IUUC-Pca-100949	Procavia capensis	82.35	0.00e+00	1220.00
IUUC-Ppe-101920	Prunus persica	33.50	5.00e-28	119.00
IUUC-Pva-102634	Pteropus vampyrus	89.44	0.00e+00	3215.00
IUUC-Rno-105870	Rattus norvegicus	97.75	0.00e+00	3642.00
IUUC-Sit-110552	Setaria italica	34.33	6.00e-29	122.00
IUUC-Sar-113289	Sorex araneus	87.52	0.00e+00	1744.00
IUUC-Ssc-115509	Sus scrofa	89.03	0.00e+00	3161.00
IUUC-Tru-117736	Takifugu rubripes	45.17	0.00e+00	837.00
IUUC-Tca-121624	Theobroma cacao	33.66	5.00e-28	119.00
IUUC-Tae-125629	Triticum aestivum	36.57	4.00e-20	93.20
IUUC-Tbe-127825	Tupaia belangeri	85.66	0.00e+00	1406.00
IUUC-Ttr-128754	Tursiops truncatus	91.76	0.00e+00	1216.00
IUUC-Xtr-132838	Xenopus tropicalis	49.19	0.00e+00	1004.00
IUUC-Xma-133119	Xiphophorus maculatus	44.36	0.00e+00	999.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence