iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.40e-21	74.5	224	254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlr 31
           +H+++v++la +d++++sGs+D t+k+WD+ 
   Q: 224  THKGWVWSLAAQDHRVCSGSWDSTVKLWDMA 254
           5********99789***************86 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDLSSGRSGD PRSCEEESDP EPDPDPDTQA EAYVARVLTP PKLGLTPRRS SLQSMFSASL 60
GVPERKAASK VPAVRLPGLL SLPPELLLEI CAYLDARVVL QVLPCVCQAL HDLVRDRVTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGATCTCG CGCTGCCTAG GAAACAAGAC GCGGCTCTGG CTAAACCTGT ACAGCCGCGC 60
CCACCCGGGC GCCATGGATC TTTCCTCAGG GCGGAGTGGG GATCCTCGCT CTTGTGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mmu:68628

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001913	Ailuropoda melanoleuca	81.88	0.00e+00	706.00
IUUC-Aca-004823	Anolis carolinensis	63.04	6.00e-149	520.00
IUUC-Bta-012687	Bos taurus	87.44	0.00e+00	719.00
IUUC-Cel-018433	Caenorhabditis elegans	25.62	7.00e-30	124.00
IUUC-Cja-018873	Callithrix jacchus	73.20	3.00e-178	618.00
IUUC-Cfa-020350	Canis familiaris	84.28	0.00e+00	716.00
IUUC-Cpo-021990	Cavia porcellus	81.22	0.00e+00	699.00
IUUC-Csa-023590	Chlorocebus sabaeus	76.74	4.00e-173	600.00
IUUC-Dre-028778	Danio rerio	41.41	5.00e-79	288.00
IUUC-Dor-030840	Dipodomys ordii	70.69	2.00e-152	532.00
IUUC-Eca-034232	Equus caballus	78.04	8.00e-166	576.00
IUUC-Fca-036533	Felis catus	86.74	0.00e+00	723.00
IUUC-Gmo-038675	Gadus morhua	44.96	4.00e-81	295.00
IUUC-Gac-041443	Gasterosteus aculeatus	43.51	3.00e-86	312.00
IUUC-Ggo-044439	Gorilla gorilla	75.22	2.00e-176	611.00
IUUC-Hsa-046835	Homo sapiens	72.17	3.00e-165	574.00
IUUC-Itr-048482	Ictidomys tridecemlineatus	85.12	0.00e+00	717.00
IUUC-Lch-049736	Latimeria chalumnae	52.01	7.00e-121	427.00
IUUC-Loc-051918	Lepisosteus oculatus	59.39	1.00e-67	248.00
IUUC-Laf-054045	Loxodonta africana	81.94	3.00e-121	427.00
IUUC-Mcc-054869	Macaca mulatta	76.98	1.00e-174	605.00
IUUC-Meu-056621	Macropus eugenii	77.42	1.00e-166	579.00
IUUC-Mmr-061740	Microcebus murinus	80.00	0.00e+00	675.00
IUUC-Mdo-062012	Monodelphis domestica	73.05	6.00e-171	593.00
IUUC-Mpu-065889	Mustela putorius furo	84.10	0.00e+00	722.00
IUUC-Mlu-067453	Myotis lucifugus	84.06	0.00e+00	696.00
IUUC-Nle-070132	Nomascus leucogenys	80.23	0.00e+00	629.00
IUUC-Opr-070719	Ochotona princeps	61.62	8.00e-136	477.00
IUUC-Ont-072613	Oreochromis niloticus	49.19	2.00e-88	319.00
IUUC-Ocu-074377	Oryctolagus cuniculus	61.68	3.00e-131	461.00
IUUC-Ola-087040	Oryzias latipes	42.26	2.00e-68	252.00
IUUC-Oga-089018	Otolemur garnettii	87.21	0.00e+00	722.00
IUUC-Oar-089327	Ovis aries	84.19	0.00e+00	691.00
IUUC-Ptr-090748	Pan troglodytes	78.00	0.00e+00	626.00
IUUC-Pan-091879	Papio anubis	78.11	4.00e-108	384.00
IUUC-Psi-093031	Pelodiscus sinensis	67.88	2.00e-175	608.00
IUUC-Pfo-096738	Poecilia formosa	45.58	1.00e-68	253.00
IUUC-Pab-097958	Pongo abelii	80.23	4.00e-174	604.00
IUUC-Pca-101049	Procavia capensis	73.13	2.00e-172	598.00
IUUC-Pva-102123	Pteropus vampyrus	81.36	0.00e+00	707.00
IUUC-Rno-105239	Rattus norvegicus	94.54	0.00e+00	835.00
IUUC-Sha-107531	Sarcophilus harrisii	78.57	2.00e-162	565.00
IUUC-Sar-113257	Sorex araneus	73.47	4.00e-168	584.00
IUUC-Ssc-115236	Sus scrofa	84.50	0.00e+00	718.00
IUUC-Tru-117762	Takifugu rubripes	45.28	3.00e-88	318.00
IUUC-Tni-120085	Tetraodon nigroviridis	44.59	4.00e-82	298.00
IUUC-Ttr-128831	Tursiops truncatus	84.86	2.00e-173	602.00
IUUC-Xtr-132712	Xenopus tropicalis	51.90	2.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence