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Tag Content
UUCD2 ID IUUC-Cja-019125
UUCD1 version UUC-CaJ-00577
Ensembl Protein ID ENSCJAP00000027223.2
UniProt Accession F7GHQ8; F7GHQ8_CALJA
Genbank Protein ID JAB36812.1
Protein Name Notchless protein homolog 1 isoform a
Genbank Nucleotide ID ACFV01049857
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000014757.2 ENSCJAT00000028777.2 ENSCJAP00000027223.2
ENSCJAG00000014757.2 ENSCJAT00000028768.1 ENSCJAP00000027214.1
ENSCJAG00000014757.2 ENSCJAT00000061903.1 ENSCJAP00000051898.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.30e-66 217.1 197 240
UBD/Beta-Prp 1.90e-78 264.6 106 299
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ ++t+l++      ++ ++++s+s Dg++++WD++ g++++
   Q: 197  GHSKWITGLSWeplhvnPEcRYVASSSKDGSVRIWDTTAGRCER 240
           8***************9889**********************86 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +sl+gh+++v +v fsp+gk+l++gs D t++ wdl t ++  t kgh + vls+s+sp+g+kl+sG +   i +wd +tg+ +  t
   Q: 106  CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLGTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRT 194
           5899************************************************************************************* PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++++++     +p++++++s+s+D+ vr+Wd   g++ r ltg ht+sv++l +  +g  l s+s+d+t+k+w  + g   r
   Q: 195  LTGHSKWITGLSWeplhvNPECRYVASSSKDGSVRIWDTTAGRCERILTG-HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCR 281
           *********98652222278899**************************9.************98.*********************** PP
   S: 217  tlnghtdnvksvrfspnde 235
           tl+gh  +v+ +++s  d 
   Q: 282  TLQGHGHWVNTMALS-TDY 299
           *************99.333 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MAAAVAEEAA VRDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDRLQLVCNA LLAQEDPLPL 60
AFFVQDAEIV SSLGKTLESQ AVETEKVLDI IYQPQAVFRV RAVTRCTSSL EGHSEAVISV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-019125|E3,WD_repeat;UBD,Beta-Prp|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCTTTCTTC TCCACGTGGG GACGCAGGAT GGCGGCGGCG GTGGCGGTGG GTGTGCGTGG 60
ATGGGGGCGG GGGCGTCACG GCGACGCTTG GGCCCGGGTC CCTGAGGCCG GAGGGAGGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-019125|E3,WD_repeat;UBD,Beta-Prp|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0042273--P:ribosomal large subunit biogenesis
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
KEGG cjc:100402225
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 58.58 4.00e-169 587.00
IUUC-Aml-001793 Ailuropoda melanoleuca 95.77 0.00e+00 937.00
IUUC-Atr-002507 Amborella trichopoda 58.64 2.00e-167 582.00
IUUC-Apl-003964 Anas platyrhynchos 85.02 0.00e+00 817.00
IUUC-Aly-006396 Arabidopsis lyrata 55.32 3.00e-162 565.00
IUUC-Ath-007278 Arabidopsis thaliana 55.53 3.00e-162 564.00
IUUC-Ago-007951 Ashbya gossypii 48.98 7.00e-131 460.00
IUUC-Acl-008298 Aspergillus clavatus 47.50 6.00e-121 427.00
IUUC-Afl-008581 Aspergillus flavus 52.38 4.00e-108 384.00
IUUC-Afu-008906 Aspergillus fumigatus 47.10 2.00e-120 425.00
IUUC-Ani-009189 Aspergillus nidulans 44.83 5.00e-116 411.00
IUUC-Ang-009630 Aspergillus niger 50.24 6.00e-123 434.00
IUUC-Aor-010038 Aspergillus oryzae 47.82 1.00e-126 446.00
IUUC-Ate-010278 Aspergillus terreus 47.00 2.00e-122 432.00
IUUC-Ame-011890 Astyanax mexicanus 81.40 0.00e+00 826.00
IUUC-Bgr-012011 Blumeria graminis 48.35 1.00e-130 459.00
IUUC-Bta-012964 Bos taurus 95.36 0.00e+00 937.00
IUUC-Bci-013592 Botrytis cinerea 45.12 5.00e-120 424.00
IUUC-Bdi-015035 Brachypodium distachyon 58.89 6.00e-171 593.00
IUUC-Bol-015501 Brassica oleracea 56.20 1.00e-162 565.00
IUUC-Bra-017642 Brassica rapa 55.98 1.00e-161 563.00
IUUC-Cel-018430 Caenorhabditis elegans 59.01 5.00e-169 587.00
IUUC-Cfa-021013 Canis familiaris 94.46 0.00e+00 849.00
IUUC-Cpo-021743 Cavia porcellus 95.35 0.00e+00 936.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 47.56 9.00e-123 433.00
IUUC-Csa-024270 Chlorocebus sabaeus 98.10 0.00e+00 952.00
IUUC-Cin-025795 Ciona intestinalis 66.10 0.00e+00 684.00
IUUC-Csv-025953 Ciona savignyi 66.74 0.00e+00 680.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 51.19 2.00e-108 385.00
IUUC-Cne-026901 Cryptococcus neoformans 49.30 6.00e-139 487.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.03 1.00e-114 406.00
IUUC-Dre-028515 Danio rerio 78.44 0.00e+00 806.00
IUUC-Dno-029596 Dasypus novemcinctus 96.19 0.00e+00 939.00
IUUC-Dor-030494 Dipodomys ordii 95.97 0.00e+00 932.00
IUUC-Dse-031538 Dothistroma septosporum 48.24 3.00e-129 455.00
IUUC-Dme-031974 Drosophila melanogaster 59.83 5.00e-168 583.00
IUUC-Ete-032948 Echinops telfairi 96.17 7.00e-117 414.00
IUUC-Eca-033399 Equus caballus 96.82 0.00e+00 939.00
IUUC-Eeu-035013 Erinaceus europaeus 93.78 4.00e-115 408.00
IUUC-Fca-035860 Felis catus 95.99 0.00e+00 937.00
IUUC-Fal-037069 Ficedula albicollis 88.00 7.00e-133 466.00
IUUC-Fox-038059 Fusarium oxysporum 46.56 5.00e-125 441.00
IUUC-Fso-038445 Fusarium solani 47.60 1.00e-125 443.00
IUUC-Gmo-039319 Gadus morhua 75.96 0.00e+00 735.00
IUUC-Ggr-040095 Gaeumannomyces graminis 47.38 2.00e-122 432.00
IUUC-Gga-040303 Gallus gallus 86.00 3.00e-131 460.00
IUUC-Gac-042267 Gasterosteus aculeatus 78.69 0.00e+00 766.00
IUUC-Gma-043974 Glycine max 57.66 4.00e-170 590.00
IUUC-Ggo-044637 Gorilla gorilla 98.30 0.00e+00 949.00
IUUC-Hsa-046128 Homo sapiens 98.31 0.00e+00 958.00
IUUC-Hvu-047373 Hordeum vulgare 58.24 1.00e-168 586.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 95.61 0.00e+00 938.00
IUUC-Kpa-049274 Komagataella pastoris 44.67 8.00e-127 447.00
IUUC-Lch-049907 Latimeria chalumnae 82.81 0.00e+00 824.00
IUUC-Lpe-050778 Leersia perrieri 54.07 2.00e-152 532.00
IUUC-Loc-051889 Lepisosteus oculatus 81.18 0.00e+00 828.00
IUUC-Lma-053041 Leptosphaeria maculans 50.35 3.00e-118 419.00
IUUC-Laf-053598 Loxodonta africana 96.41 0.00e+00 944.00
IUUC-Mcc-055660 Macaca mulatta 97.89 0.00e+00 951.00
IUUC-Meu-056197 Macropus eugenii 79.96 0.00e+00 776.00
IUUC-Mor-056949 Magnaporthe oryzae 46.38 3.00e-119 422.00
IUUC-Mpo-057571 Magnaporthe poae 44.07 2.00e-62 233.00
IUUC-Mtr-058530 Medicago truncatula 58.94 9.00e-168 583.00
IUUC-Mla-059133 Melampsora laricipopulina 46.34 1.00e-124 439.00
IUUC-Mga-059252 Meleagris gallopavo 84.93 0.00e+00 665.00
IUUC-Mvi-060522 Microbotryum violaceum 49.59 8.00e-136 477.00
IUUC-Mmr-061117 Microcebus murinus 96.00 0.00e+00 934.00
IUUC-Mdo-062892 Monodelphis domestica 89.22 0.00e+00 887.00
IUUC-Mmu-064108 Mus musculus 95.98 0.00e+00 911.00
IUUC-Mac-064430 Musa acuminata 59.31 2.00e-172 598.00
IUUC-Mpu-065882 Mustela putorius furo 95.14 0.00e+00 928.00
IUUC-Mlu-068123 Myotis lucifugus 95.99 0.00e+00 945.00
IUUC-Nfi-068484 Neosartorya fischeri 47.18 5.00e-120 424.00
IUUC-Ncr-068649 Neurospora crassa 43.45 7.00e-115 407.00
IUUC-Nle-069140 Nomascus leucogenys 97.88 0.00e+00 946.00
IUUC-Opr-070220 Ochotona princeps 88.75 0.00e+00 816.00
IUUC-Ont-072643 Oreochromis niloticus 80.84 0.00e+00 824.00
IUUC-Ocu-074007 Oryctolagus cuniculus 96.19 0.00e+00 910.00
IUUC-Oba-075904 Oryza barthii 59.31 5.00e-172 597.00
IUUC-Obr-076280 Oryza brachyantha 58.67 8.00e-171 593.00
IUUC-Ogl-077425 Oryza glaberrima 59.31 3.00e-172 597.00
IUUC-Ogu-078586 Oryza glumaepatula 59.31 4.00e-172 597.00
IUUC-Oin-079489 Oryza indica 57.17 4.00e-163 567.00
IUUC-Olo-080766 Oryza longistaminata 59.19 6.00e-172 597.00
IUUC-Ome-081905 Oryza meridionalis 59.31 4.00e-172 597.00
IUUC-Oni-083022 Oryza nivara 59.31 2.00e-172 598.00
IUUC-Opu-083615 Oryza punctata 59.31 3.00e-172 597.00
IUUC-Oru-085076 Oryza rufipogon 59.31 2.00e-172 598.00
IUUC-Osa-085516 Oryza sativa 59.31 2.00e-172 598.00
IUUC-Ola-087290 Oryzias latipes 79.16 0.00e+00 810.00
IUUC-Olu-087898 Ostreococcus lucimarinus 52.83 2.00e-144 505.00
IUUC-Oga-088980 Otolemur garnettii 95.75 0.00e+00 931.00
IUUC-Oar-089580 Ovis aries 95.37 0.00e+00 813.00
IUUC-Ptr-090845 Pan troglodytes 97.45 0.00e+00 940.00
IUUC-Pan-092836 Papio anubis 98.10 0.00e+00 953.00
IUUC-Psi-093965 Pelodiscus sinensis 82.46 2.00e-55 206.00
IUUC-Pno-095052 Phaeosphaeria nodorum 47.43 5.00e-123 434.00
IUUC-Ppa-095432 Physcomitrella patens 58.64 4.00e-170 590.00
IUUC-Pfo-096963 Poecilia formosa 72.63 0.00e+00 709.00
IUUC-Pab-097716 Pongo abelii 94.06 0.00e+00 900.00
IUUC-Pop-099224 Populus trichocarpa 58.94 2.00e-171 595.00
IUUC-Pca-100682 Procavia capensis 92.96 0.00e+00 681.00
IUUC-Ppe-101819 Prunus persica 58.85 4.00e-170 590.00
IUUC-Pva-102338 Pteropus vampyrus 95.53 0.00e+00 713.00
IUUC-Pgr-103583 Puccinia graminis 54.50 7.00e-132 464.00
IUUC-Ptt-103737 Puccinia triticina 44.34 5.00e-100 358.00
IUUC-Pte-104150 Pyrenophora teres 50.57 2.00e-122 432.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 50.57 3.00e-122 432.00
IUUC-Rno-105987 Rattus norvegicus 95.76 0.00e+00 933.00
IUUC-Sce-106315 Saccharomyces cerevisiae 47.67 2.00e-130 459.00
IUUC-Sha-107273 Sarcophilus harrisii 90.49 0.00e+00 901.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 46.54 5.00e-119 421.00
IUUC-Spo-108092 Schizosaccharomyces pombe 49.20 6.00e-124 437.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 44.26 1.00e-115 409.00
IUUC-Smo-108855 Selaginella moellendorffii 55.44 1.00e-163 569.00
IUUC-Sit-110329 Setaria italica 59.31 2.00e-171 595.00
IUUC-Sly-111830 Solanum lycopersicum 60.39 7.00e-175 606.00
IUUC-Stu-112603 Solanum tuberosum 60.39 7.00e-175 606.00
IUUC-Sar-113504 Sorex araneus 89.44 5.00e-72 265.00
IUUC-Sbi-114560 Sorghum bicolor 58.03 3.00e-168 584.00
IUUC-Sre-115133 Sporisorium reilianum 41.62 7.00e-124 437.00
IUUC-Ssc-115903 Sus scrofa 95.99 0.00e+00 936.00
IUUC-Tgu-116798 Taeniopygia guttata 85.20 0.00e+00 856.00
IUUC-Tru-118361 Takifugu rubripes 78.74 0.00e+00 806.00
IUUC-Tsy-118849 Tarsius syrichta 96.60 0.00e+00 936.00
IUUC-Tni-120094 Tetraodon nigroviridis 79.75 0.00e+00 808.00
IUUC-Tca-121634 Theobroma cacao 58.72 1.00e-168 585.00
IUUC-Tre-122051 Trichoderma reesei 45.62 2.00e-118 419.00
IUUC-Tvi-122322 Trichoderma virens 46.78 3.00e-122 431.00
IUUC-Tae-123133 Triticum aestivum 58.46 1.00e-169 589.00
IUUC-Tur-126766 Triticum urartu 52.19 8.00e-161 560.00
IUUC-Tme-127175 Tuber melanosporum 51.37 6.00e-132 464.00
IUUC-Tbe-127779 Tupaia belangeri 94.85 0.00e+00 828.00
IUUC-Ttr-128224 Tursiops truncatus 90.65 0.00e+00 803.00
IUUC-Uma-129537 Ustilago maydis 41.82 3.00e-124 439.00
IUUC-Vda-129927 Verticillium dahliae 45.61 2.00e-111 395.00
IUUC-Vpa-130658 Vicugna pacos 83.65 0.00e+00 790.00
IUUC-Vvi-131659 Vitis vinifera 59.06 3.00e-171 594.00
IUUC-Xtr-132918 Xenopus tropicalis 77.68 0.00e+00 791.00
IUUC-Xma-133700 Xiphophorus maculatus 80.84 0.00e+00 821.00
IUUC-Yli-134478 Yarrowia lipolytica 50.31 3.00e-138 485.00
IUUC-Zma-135835 Zea mays 55.58 3.00e-165 575.00
Created Date 25-Jun-2017

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