iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036550

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02138576

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022746.1	ENSFCAT00000029267.1	ENSFCAP00000020575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.60e-61	206.6	19	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 137  knkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........................................ 185
            ++s+++  Fq q++s+++c++c ++s++++pfl +slp+p ++++ ++                                        
   Q: 19   LGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSvtlvfpsksqrflrvglavpilstvaslrkmvaeeggvpa 107
           5689****************************************98888**************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 108  devilvelcpsgfqrsffdeedlntiaegdnvyafhappppgqemlsahppglsisprlaahggqrlpppvqsenkvlillcnlagsgq 196
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 197  qasrfgppfliredraiswvqlqqcilskvrylmkseaplqqnpgslfsirvvglslacsylspqdshplshwavdralhprrpggpph 285
           ***************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLil 232
                                                     +l++c++ +tkee+l ++++++c++ck++q+ + kl+l++lP++Li+
   Q: 286  vklavewdsdakgrlfgspqeervqdaesvwrqqeahqqpscTLDECFQFYTKEEQLAQDDAWKCPHCKALQQGTVKLSLWTLPDILII 374
           ***************************************************************************************** PP
   S: 233  hLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke....................kkkYeLiavvvHsGslssGHYvayvk 300
           hLkRf   + +++r+k+++ v+fpl+ L+++p++++++ + k                     +  Y+L+av++H+G+l++GHY+ay++
   Q: 375  HLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAQRNAGPKPatgpwpsweqpaclpascpwDFLYDLYAVCNHHGGLQGGHYTAYCR 461
           *****..88899************************888877799999999999*********************************** PP
   S: 301  n.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           n  +g+W+ fdDs+V++++e+ev +   + aY+lfY++r
   Q: 462  NsLDGQWYSFDDSTVEPLPEDEVST---RGAYILFYQKR 497
           *55788*******************...********985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

PEASRTPEHL LSPSAQLPLG QSFVQSHFQA QYRSSLTCPH CLKQSNTFDP FLCVSLPIPL 60
RQTRFLSVTL VFPSKSQRFL RVGLAVPILS TVASLRKMVA EEGGVPADEV ILVELCPSGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGAAGCCA GCAGAACCCC TGAGCACCTC CTGTCCCCAT CGGCTCAGCT TCCCCTAGGC 60
CAAAGCTTTG TGCAAAGCCA CTTTCAAGCC CAGTATAGGT AAGAATCTAG GTAAGGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	76.82	0.00e+00	1313.00
IUUC-Aca-004436	Anolis carolinensis	50.22	0.00e+00	721.00
IUUC-Ame-011153	Astyanax mexicanus	45.74	0.00e+00	656.00
IUUC-Bta-013560	Bos taurus	74.97	0.00e+00	1285.00
IUUC-Cja-018737	Callithrix jacchus	72.36	0.00e+00	1213.00
IUUC-Cfa-020347	Canis familiaris	77.27	0.00e+00	1313.00
IUUC-Csa-023656	Chlorocebus sabaeus	74.16	0.00e+00	1222.00
IUUC-Cho-024864	Choloepus hoffmanni	64.18	5.00e-180	624.00
IUUC-Dre-028066	Danio rerio	45.56	0.00e+00	679.00
IUUC-Dno-028855	Dasypus novemcinctus	68.88	0.00e+00	1053.00
IUUC-Dor-030475	Dipodomys ordii	84.26	0.00e+00	694.00
IUUC-Dme-032088	Drosophila melanogaster	35.81	6.00e-76	279.00
IUUC-Eca-034147	Equus caballus	79.26	0.00e+00	1130.00
IUUC-Eeu-034703	Erinaceus europaeus	65.96	6.00e-127	448.00
IUUC-Gac-042087	Gasterosteus aculeatus	45.77	0.00e+00	645.00
IUUC-Ggo-045171	Gorilla gorilla	74.27	0.00e+00	1222.00
IUUC-Hsa-045961	Homo sapiens	74.38	0.00e+00	1224.00
IUUC-Loc-052852	Lepisosteus oculatus	47.80	0.00e+00	698.00
IUUC-Laf-054033	Loxodonta africana	71.29	0.00e+00	1186.00
IUUC-Mcc-055431	Macaca mulatta	74.59	0.00e+00	1238.00
IUUC-Meu-056444	Macropus eugenii	67.53	4.00e-114	405.00
IUUC-Mmr-061035	Microcebus murinus	75.81	0.00e+00	1254.00
IUUC-Mdo-062172	Monodelphis domestica	64.94	0.00e+00	755.00
IUUC-Mmu-063966	Mus musculus	67.56	0.00e+00	1104.00
IUUC-Mpu-066307	Mustela putorius furo	76.60	0.00e+00	1259.00
IUUC-Nle-070172	Nomascus leucogenys	73.62	0.00e+00	1212.00
IUUC-Opr-070499	Ochotona princeps	84.88	0.00e+00	852.00
IUUC-Ont-071920	Oreochromis niloticus	45.71	0.00e+00	668.00
IUUC-Ocu-074014	Oryctolagus cuniculus	75.25	0.00e+00	1003.00
IUUC-Ola-086360	Oryzias latipes	55.59	0.00e+00	662.00
IUUC-Oga-088202	Otolemur garnettii	73.84	0.00e+00	1235.00
IUUC-Oar-089819	Ovis aries	75.30	0.00e+00	1300.00
IUUC-Ptr-091076	Pan troglodytes	74.49	0.00e+00	1228.00
IUUC-Pan-092248	Papio anubis	73.95	0.00e+00	1217.00
IUUC-Pfo-096332	Poecilia formosa	56.18	0.00e+00	652.00
IUUC-Pab-098453	Pongo abelii	74.16	0.00e+00	1224.00
IUUC-Pca-100290	Procavia capensis	56.65	0.00e+00	644.00
IUUC-Pva-102317	Pteropus vampyrus	80.35	0.00e+00	731.00
IUUC-Rno-104948	Rattus norvegicus	68.30	0.00e+00	1090.00
IUUC-Sha-106558	Sarcophilus harrisii	51.95	0.00e+00	855.00
IUUC-Sar-113105	Sorex araneus	59.11	0.00e+00	912.00
IUUC-Ssc-115312	Sus scrofa	75.87	0.00e+00	1253.00
IUUC-Tru-117995	Takifugu rubripes	59.20	0.00e+00	665.00
IUUC-Tsy-119325	Tarsius syrichta	69.37	5.00e-178	618.00
IUUC-Tni-120517	Tetraodon nigroviridis	54.91	0.00e+00	636.00
IUUC-Tbe-127439	Tupaia belangeri	58.33	9.00e-98	351.00
IUUC-Ttr-128829	Tursiops truncatus	67.39	0.00e+00	1078.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence