iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106558

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01181038

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002977.1	ENSSHAT00000003423.1	ENSSHAP00000003387.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-92	310.5	98	711

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l   + ++ +        +e++++l+ l+++lw+++ +     e++++++k+ ++f+g+ q
   Q: 98   QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGHYRARP------GRAEVTEQLAGLVRALWTRDYTPHLSVEFKNTVSKYGSQFQGNLQ 180
           6****************************994444444......4579***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l++++  + +e+   ++++l+++   +++ +++ +s++++ Fq q++s+++c++c+++s++++pfl +slp+
   Q: 181  HDALEFLLWLLDRVHEDLDSSSPGQSSEKVAVEERTLESQpgPSKNCPSQRQSFVQNHFQAQYRSSLTCPHCQKQSNTFDPFLCVSLPI 269
           ******************8866655555555555544444447888899999************************************* PP
   S: 177  pgkeetkke................................................................................ 185
           p+ ++++++                                                                                
   Q: 270  PSCQTRSLNvtlvfqsknqrflriglavplfstvatlrkmvaeeskitanevvlvelspngfqrsffdeedlntiseednvyafqasws 358
           ****99888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 359  piwgvpatfsvqpqyqasspqillqdsclasltlhwngskviillcnlvgsghkakrfgpplllredraiswdqlrqqvfnkmrylikq 447
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 448  evpmqqslgslfavrvvglsnicsylspqdsrplfhwaverslklskpgspphiklavewdrnikqllfgniqeevvrdapsvqlqqqa 536
           ***************************************************************************************** PP
   S: 186  ......slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts 267
                 +l++c++ +tkee+l  +++++c++ck +q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl  L+++p++++
   Q: 537  hqqpscTLNECFQLYTKEEQLAPDDAWKCPHCKVLQQGMVKLSLWTLPDILIIHLKRF--CQVGGRRNKLSTLVKFPLYgLNMAPHVAK 623
           **********************************************************..8999************************* PP
   S: 268  peekqke...................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +q+                    +  Y+L+av++H+Gs+++GHY+ay++n  +g+W+ +dDs+V++v e+e+ +   + aY+lfY+
   Q: 624  RNFGQEClnswpsweqasclpnscsfDFLYDLYAVCNHHGSMQGGHYTAYCRNsLDGQWYSYDDSTVEPVLEDEIST---QGAYILFYQ 709
           55554337777777777788888888***************************55788*******************...********9 PP
   S: 337  rr 338
           +r
   Q: 710  KR 711
           85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MTDPGTAAAA YVQARGGPPS SRHRRSFRRL LGSFLRVLGV LSRSRGSPSR TQPGVEQNDP 60
DPGSSDSTWP AKEVSWEAGD ALLPQPLPRD KARPPGTQGL KNHGNTCFMN AVVQCLSNTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGACC CGGGAACAGC CGCGGCGGCC TATGTCCAGG CACGTGGGGG ACCACCCTCT 60
TCTCGTCACC GCCGCTCCTT TCGCCGTCTT TTGGGCAGTT TTCTGCGAGT TCTGGGTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	54.80	0.00e+00	962.00
IUUC-Aca-004436	Anolis carolinensis	57.67	0.00e+00	756.00
IUUC-Ame-011153	Astyanax mexicanus	55.97	0.00e+00	854.00
IUUC-Bta-013560	Bos taurus	57.47	0.00e+00	1088.00
IUUC-Cel-018710	Caenorhabditis elegans	25.76	8.00e-45	176.00
IUUC-Cja-018737	Callithrix jacchus	57.88	0.00e+00	1082.00
IUUC-Cfa-020347	Canis familiaris	56.78	0.00e+00	1034.00
IUUC-Csa-023656	Chlorocebus sabaeus	58.67	0.00e+00	1114.00
IUUC-Cho-024864	Choloepus hoffmanni	58.09	0.00e+00	699.00
IUUC-Dre-028066	Danio rerio	47.24	0.00e+00	863.00
IUUC-Dno-028855	Dasypus novemcinctus	59.50	0.00e+00	1018.00
IUUC-Dor-030475	Dipodomys ordii	48.06	0.00e+00	691.00
IUUC-Dme-032088	Drosophila melanogaster	36.59	2.00e-110	393.00
IUUC-Eca-034147	Equus caballus	65.54	0.00e+00	1032.00
IUUC-Eeu-034703	Erinaceus europaeus	59.08	4.00e-108	385.00
IUUC-Fca-036550	Felis catus	51.95	0.00e+00	835.00
IUUC-Gac-042087	Gasterosteus aculeatus	56.63	0.00e+00	780.00
IUUC-Ggo-045171	Gorilla gorilla	58.40	0.00e+00	1113.00
IUUC-Hsa-045961	Homo sapiens	58.94	0.00e+00	1119.00
IUUC-Loc-052852	Lepisosteus oculatus	58.06	0.00e+00	886.00
IUUC-Laf-054033	Loxodonta africana	58.76	0.00e+00	1063.00
IUUC-Mcc-055431	Macaca mulatta	58.77	0.00e+00	1122.00
IUUC-Meu-056444	Macropus eugenii	83.33	4.00e-143	502.00
IUUC-Mmr-061035	Microcebus murinus	58.52	0.00e+00	1061.00
IUUC-Mdo-062172	Monodelphis domestica	76.58	0.00e+00	1187.00
IUUC-Mmu-063966	Mus musculus	58.41	0.00e+00	1083.00
IUUC-Mpu-066307	Mustela putorius furo	56.60	0.00e+00	987.00
IUUC-Nle-070172	Nomascus leucogenys	59.07	0.00e+00	1116.00
IUUC-Opr-070499	Ochotona princeps	53.79	0.00e+00	979.00
IUUC-Ont-071920	Oreochromis niloticus	58.01	0.00e+00	858.00
IUUC-Ocu-074014	Oryctolagus cuniculus	64.76	0.00e+00	886.00
IUUC-Oga-088202	Otolemur garnettii	55.87	0.00e+00	1063.00
IUUC-Oar-089819	Ovis aries	55.85	0.00e+00	1017.00
IUUC-Ptr-091076	Pan troglodytes	59.04	0.00e+00	1118.00
IUUC-Pan-092248	Papio anubis	58.67	0.00e+00	1112.00
IUUC-Pfo-096332	Poecilia formosa	56.23	0.00e+00	819.00
IUUC-Pab-098453	Pongo abelii	56.91	0.00e+00	1059.00
IUUC-Pca-100290	Procavia capensis	45.03	4.00e-130	459.00
IUUC-Pva-102317	Pteropus vampyrus	50.70	0.00e+00	883.00
IUUC-Rno-104948	Rattus norvegicus	55.57	0.00e+00	959.00
IUUC-Sar-113105	Sorex araneus	53.38	0.00e+00	744.00
IUUC-Ssc-115312	Sus scrofa	58.05	0.00e+00	1091.00
IUUC-Tru-117995	Takifugu rubripes	59.52	0.00e+00	859.00
IUUC-Tsy-119325	Tarsius syrichta	60.31	3.00e-163	568.00
IUUC-Tni-120517	Tetraodon nigroviridis	55.69	0.00e+00	814.00
IUUC-Tbe-127439	Tupaia belangeri	49.06	4.00e-53	203.00
IUUC-Ttr-128829	Tursiops truncatus	51.78	0.00e+00	926.00
IUUC-Vpa-130306	Vicugna pacos	62.59	4.00e-133	469.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence